VolverListar por autor "Irastorza, Inaki"
Mostrando ítems 1-10 de 10
-
A Novel Noninvasive Method Based on Salivary Inflammatory Biomarkers for the Screening of Celiac Disease
Sebastián de la Cruz, Maialen
; ; ; ; ; Fernández Jiménez, Nora ; ; ; ; ; ; Irastorza Terradillos, Iñaki Xarles ; Bujanda Fernández de Pierola, Luis ; Bilbao Catalá, José Ramón ; Castellanos Rubio, Ainara (Elsevier, 2021)
... -
Accuracy in Copy Number Calling by qPCR and PRT : A Matter of DNA
; ; ; ; Irastorza Terradillos, Iñaki Xarles; Castaño González, Luis Antonio ; ; Bilbao Catalá, José Ramón (Public Library of Science, 2011-12-13)
The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the ... -
Alimentación y cáncer: dime qué comes y te diré cómo te sienta.
(2019-01-17)[ES] El cáncer se ha convertido en una de las enfermedades más prevalentes del siglo XXI, con un importante impacto sanitario, económico y personal. Es una de las principales causas de muerte en todos los países del mundo, ... -
Celiac Diasease-associated lncRNA Named HCG14 Regulates NOD1 Expression in Intestinal Cells
; ; ; ; ; ; Fernández Jiménez, Nora; Irastorza Terradillos, Iñaki Xarles ; Castaño González, Luis Antonio ; Bilbao Catalá, José Ramón (Wiley, 2018-08-01)
Objective: The aim of the study is to identify additional celiac disease associated loci in the major histocompatibility complex (MHC) independent from classical HLA risk alleles (HLA-DR3-DQ2) and to characterize their ... -
Celiac disease in the Mediterranean area
Tucci, Francesca; Astarita, Luca; Abkari, Abdelhak; Abu-Zekry, Mona; Attard, Thomas; Ben Hariz, Mongi; Bilbao Catalá, José Ramón; Boudraa, Ghazalia; Boukthir, Samir; Costa, Stefano; Djurisic, Veselinka; Hugot, Jean-Pierre; Irastorza Terradillos, Iñaki Xarles ; Kansu, Aydan; Kolacek, Sanja; Magazzu, Giuseppe; Micetic-Turk, Dusanka; Misak, Zrinjka; Roma, Eleftheria; Rossi, Pasqualino; Terzic, Selma; Velmishi, Virtut; Arcidiaco, Carmela; Auricchio, Renata; Greco, Luigi; (BioMed Central, 2014-02)
Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe ... -
Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells
Olazagoitia Garmendia, Ane; Zhang, Linda; Mera, Paula; Godbout, Julie K.; Sebastián de la Cruz, Maialen; García Santisteban, Iraia ; Mendoza Gómez, Luis Manuel; Huerta Madrigal, Alain; Irastorza Terradillos, Iñaki Xarles ; Bhagat, Govind; Green, Peter H.; Herrero, Laura; Serra, Dolors; Rodríguez Pérez, José Antonio ; Verdú, Elena F.; He, Chuan; Bilbao Catalá, José Ramón ; Castellanos Rubio, Ainara (BMJ, 2022-01)
[EN] Objectives Coeliac disease (CD) is a complex autoimmune disorder that develops in genetically susceptible individuals. Dietary gluten triggers an immune response for which the only available treatment so far is a ... -
MAGI2 Gene Region and Celiac Disease
; ; García Etxebarria, Koldo; Olazagoitia Garmendia, Ane; Romero Garmendia, Irati; Sebastián de la Cruz, Maialen; Irastorza Terradillos, Iñaki Xarles ; Spanish Consortium for the Genetics of Celiac Disease; Castellanos Rubio, Ainara; Bilbao Catalá, José Ramón (Frontiers Media, 2019-12-19)
Celiac disease (CD) patients present a loss of intestinal barrier function due to structural alterations in the tight junction (TJ) network, the most apical unions between epithelial cells. The association of TJ-related ... -
Sex bias in celiac disease: XWAS and monocyte eQTLs in women identify TMEM187 as a functional candidate gene
; Cilleros Portet, Ariadna; ; ; ; ; ; García Santisteban, Iraia ; Irastorza Terradillos, Iñaki Xarles ; Fernández Jiménez, Nora ; Bilbao Catalá, José Ramón (BMC, 2023-12)
Background Celiac disease (CeD) is an immune-mediated disorder that develops in genetically predisposed individuals upon gluten consumption. HLA risk alleles explain 40% of the genetic component of CeD, so there have ... -
The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region
Fernández Jiménez, Nora; ; ; ; ; ; ; ; ; ; ; Irastorza Terradillos, Iñaki Xarles ; ; ; Bilbao Catalá, José Ramón (Nature Publishing, 2019-02-04)
The Human Leucocyte Antigen (HLA) locus and other DNA sequence variants identified in Genome-Wide Association (GWA) studies explain around 50% of the heritability of celiac disease (CD). However, the pathogenesis of CD ... -
Transcription Factor Binding Site Enrichment Analysis In Co-Expression Modules In Celiac Disease
Romero Garmendia, Irati; García Etxebarria, Koldo; Hernández Vargas, Hector; ; ; Plaza Izurieta, Leticia; Cros, Marie-Pierre; Legarda Tamara, María; Irastorza Terradillos, Iñaki Xarles; Herceg, Zdenko; Fernández Jiménez, Nora ; Bilbao Catalá, José Ramón (MDPI, 2018-05-10)
The aim of this study was to construct celiac co-expression patterns at a whole genome level and to identify transcription factors (TFs) that could drive the gliadin-related changes in coordination of gene expression ...