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Now showing items 19268-19287 of 39309
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Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts
Bortolomeazzi, Michele; Keddar, Mohamed Reda; Montorsi, Lucia; Acha-Sagredo, Amelia; Benedetti, Lorena; Temelkovski, Damjan; Choi, Subin; Petrov, Nedyalko; Todd, Katrina; Wai, Patty; Kohl, Johannes; Denner, Tamara; Nye, Emma; Goldstone, Robert; Ward, Sophia; Wilson, Gareth A.; Al Bakir, Maise; Swanton, Charles; John, Susan; Miles, James; Larijani, Banafshé
; Kunene, Victoria; Fontana, Elisa; Arkenau, Hendrik-Tobias; Parker, Peter J.; Rodriguez-Justo, Manuel; Shiu, Kai-Keen; Spencer, Jo; Ciccarelli, Francesca D. (Elsevier, 2021-10)
BACKGROUND & AIMS: Colorectal cancer (CRC) shows variable response to immune checkpoint blockade, which can only partially be explained by high tumor mutational burden (TMB). We conducted an integrated study of the cancer ... -
Immunoglobulina G4-rekin erlazionaturiko gaixotasuna: epe luzerako pronostikoa. Gaixoberritze eta gaiztotze arriskua.
(2019-01-18)[EUS] Immunoglobulina G4-rekin erlazionaturiko gaixotasuna (IgG4-EG) duela gutxi deskribatutako eritasuna da. IgG4-EGren bereizgarri dira serumeko IgG4 kontzentrazioaren igoera, infiltratu linfoplasmatikoa, fibrosi ... -
Immunohistochemical Characterisation of the Whale Retina
Ruzafa Andrés, Noelia; Pereiro Díez, Xandra ; Vecino Cordero, Elena (Frontiers Media, 2022)
[EN] The eye of the largest adult mammal in the world, the whale, offers a unique opportunity to study the evolution of the visual system and its adaptation to aquatic environments. However, the difficulties in obtaining ... -
Immunoproteomics-Based Analysis of the Immunocompetent Serological Response to Lomentospora prolificans
; ; ; Antorán Díaz, Aitziber; ; (ACS, 2016-01-06)
The filamentous fungus Lomentospora prolificans is an emerging pathogen causing severe infections mainly among the immunocompromised population. These diseases course with high mortality rates due to great virulence of the ... -
Immunoterapiaren eragin potentzialak bularreko minbizian
(2021-12-02)Gaur egun bularreko minbizia minbizien artean emakumeetan lehen heriotza kausa suposatzen du. Gaixotasunaren kasuek gora egin dute XX. mendeko erdialdetik herrialde garatu eta garapen bidean daudenetan. Hala ere, ezagunak ... -
Imotz, Basaburu Nagusia, Larraun eta Araitz-Betelu ibarretako lexikoaren azterketa
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2007)In this study we have analysed the lexical characteristics of the Basque language that is spoken in the North West Nafarroa's four valleys: Imo-tz, Basaburu Nagusia, Larraun and Arai-tz-Betelu. Our main objective is to ... -
Imozko oikonimiaz
(2017-11-23)“Imozko oikonimiaz” izena duen Gradu Amaierako Lan (GRAL) honek Imozko oikonimia eta bertatik eratorritako izengoitiak aztertzea du helburu, honako gaia Euskal Herriko beste alderdi batzuetan landu duten adituen lanak ... -
Impact analysis of wind farms on telecommunication services
Angulo Pita, Itziar; De la Vega Moreno, David ; ; ; ; ; Angueira Buceta, Pablo (Elsevier, 2014-01-25)
[EN] Wind power is one of the fastest-growing technologies for renewable energy generation. Unfortunately, in the recent years some cases of degradation on certain telecommunication systems have arisen due to the presence ... -
Impact and distribution of climatic damages: a methodological proposal with a dynamic CGE model applied to global climate negotiations
(Springer Nature, 2018)The UNFCCC Paris Agreement, entered into force on 4 November 2016, represents a step forward in involving all countries in mitigation actions, even though it is based on a voluntary approach and lacks the active participation ... -
Impact assessment of policy expressivenessof an optimised access control model forsmart sensors
Uriarte, Mikel; Astorga Burgo, Jasone; Jacob, Eduardo; Huarte Arrayago, Maider ; López, Oscar (IET, 2019-05)
In the incoming internet of things (IoT) applications, smart sensors expose services to interact with them, to be parameterised, managed and maintained. Therefore, fine-grained end-to-end access control enforcement is ... -
Impact of a resistive superconductive fault current limiter in a multi-terminal HVDC grid
; ; Larruscain Escobal, Dunixe Marene; ; (IEEE, 2018-06-11)
The relevance of multi-terminal HVDC grids is expected to increase in next years. However, there are still several technical, economical and legal limitations that interfere with the construction of those multi-terminal ... -
Impact of a teaching strategy to promote evidence-based practice on nursing students’ knowledge and confidence in simulated clinical intervention choices
(BMC, 2023)Background Nurses self-efficacy, confidence and their competency for evidence-based practice have a relevant impact in the quality of care provided to patients. However, the implementation of evidence-based practice ... -
Impact of a workplace ‘sit less, move more’ program on efficiency-related outcomes of office employees
Puig-Ribera, Anna; Bort-Roig, Judit; Giné-Garriga, María; González Suárez, Ángel Manuel; Martínez-Lemos, Iván; Fortuño, Jesús; Martori, Joan C.; Muñoz-Ortiz, Laura; Milà, Raimon; D. Gilson, Nicholas; McKenna, Jim (Biomed Central, 2017-05-10)
Background: Few studies have examined the impact of 'sit less, move more' interventions on workplace performance. This study assessed the short and mid-term impacts of and patterns of change within, a 19-week workplace ... -
Impact of adverse childhood experiences on educational achievements in young people at clinical high risk of developing psychosis
; Catalán Alcántara, Ana; ; (Oxford University Press, 2023-01)
BACKGROUND: Adverse childhood experiences (ACE) can affect educational attainments, but little is known about their impact on educational achievements in people at clinical high risk of psychosis (CHR). METHODS: In ... -
Impact of Augmented Renal Clearance in Critically Ill Patients: Population Pharmacokinetics of Levetiracetam and Dosing Evaluation
(2022-06-27)Introduction: Augmented renal clearance (ARC) is a phenomenon recently identified in critically ill patients.ARC has the potential to influence the pharmacokinetic profile of any drug that is renally cleared andknown to ... -
Impact of augmented renal clearance on the pharmacokinetics of linezolid: Advantages of continuous infusion from a pharmacokinetic/pharmacodynamic perspective
Barrasa González, Helena; Soraluce Olañeta, Amaia; Usón, Elena; Sainz, Javier; Martín, Alejandro; Sánchez Izquierdo, José Ángel; Maynar, Javier; ; Isla Ruiz, Arantxazu (Elsevier, 2020-04)
Objectives: The aim of this study was to assess the influence of renal function, in particular the presence of augmented renal clearance (ARC), on the pharmacokinetics of linezolid in critically ill patients. The effect ... -
Impact of Channel Disturbances on Current Narrowband Power Line Communications and Lessons to Be Learnt for the Future Technologies
; De la Vega Moreno, David; Angulo Pita, Itziar ; (IEEE, 2019-06-24)
[EN] The electricity network is a complex communication medium with properties that depend on both the topology of the grid and the usage pattern of the connected devices. These devices generate channel disturbances during ... -
Impact of Charge-Resonance Excitations on CT-Mediated J-Type Aggregation in Singlet and Triplet Exciton States of Perylene Di-Imide Aggregates: A TDDFT Investigation
(MDPI, 2022-01-25)The modulation of intermolecular interactions upon aggregation induces changes in excited state properties of organic molecules that can be detrimental for some optoelectronic applications but can be exploited for others. ... -
Impact of chronic hepatitis C on mortality in cirrhotic patients admitted to intensive-care unit
; ; ; Medrano Laporte, José; ; ; (Biomed Central, 2016-03-12)
Background: Cirrhosis and severe sepsis are factors associated with increased mortality in intensive care unit (ICU), but chronic hepatitis C (CHC) has been less studied in ICU. The aim of this study was to analyze the ... -
The impact of CLIL: affective factors, content-related vocabulary & gender differences
(2016-06-03)[EN] The experiment discussed in this paper is a direct replication of Finkbeiner (2005) and an indirect replication of Jiang and Forster (2001) and Witzel and Forster (2012). The paper explores the use of episodic memory ...