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Now showing items 9822-9841 of 40242
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Development and characterization of non-viral vectors based on cationic niosomes to address cystic fibrosis disease by gene therapy approach
(2022-03-17)Gene therapy is based on the delivery of exogenous genetic material into target cells to modulate theexpression of an altered genome in order to treat a specific disease. Lipid nanocarriers, such as niosomesbased on cationic ... -
Development and comparative analysis of the modeling of an innovative finned-plate latent heat thermal energy storage system
(Elsevier, 2013-09-01)This paper presents an innovative finned-plate latent heat thermal energy storage system for its integration in cogeneration systems. For optimization purposes it is very important to maximize the efficiency of the ... -
Development and evaluation of a comprehensive workflow for suspect screening of exposome-related xenobiotics and phase II metabolites in diverse human biofluids
(Elsevier, 2024-01-13)Suspect and non-target screening (SNTS) methods are being promoted in order to decode the human exposome since a wide chemical space can be analysed in a diversity of human biofluids. However, SNTS approaches in the ... -
Development and evaluation of different electroactive poly(vinylidene fluoride) architectures for endothelial cell culture
(Frontiers Media, 2022)Tissue engineering (TE) aims to develop structures that improve or even replace the biological functions of tissues and organs. Mechanical properties, physical-chemical characteristics, biocompatibility, and biological ... -
Development and evaluation of non-viral gene delivery vectors and their combination with hydrogel scaffold technology
(2018-10-26)Nanotechnology-based non-viral vectors have emerged as promising alternatives to viruses to carry genetic material into target cells due to their ability to overcome many limitations of viral vectors. Although very efficient, ... -
Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients
(Biomed Central, 2016-08-31)Background: Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and ... -
Development and Implementation of a Community-Based Research Network
(Cambridge University Press, 2020-05-18)Introduction: People aging with long-term physical disabilities (PAwLTPD), meaning individuals with onset of disability from birth through midlife, often require long-term support services (LTSS) to remain independence. ... -
Development and implementation of new analytical methodologies for the study of aciditfication in estuaries
(2018-03-09)Siendo la acidificación de los océanos un tema candente en las últimas décadas, muy poco se ha avanzado en lo que acidificación en estuarios se refiere, fundamentalmente en lo relativo al tratamiento de los datos obtenidos ... -
Development and Industrialization Pathways of Quasi-Solid-State Electrolytes for primary Zinc-Air Batteries
(2024-03-22)This doctoral thesis focuses on enhancing the performance of primary zinc-air batteries marketed by the Spanish company Cegasa. Following a thorough analysis of the EZ8 6/50, the choice and design of the quasi-solid ... -
Development and integration of In Silico and In Vitro tools for comprehensive prediction and characterization of genetic variants in Familial Hypercholesterolemia and Hyperlipidemias
(2024-01-12)El objetivo de mi tesis se centra en el desarrollo de técnicas in silico e in vitro para la predicción y caracterización de variantes causantes de hipercolesterolemia familiar e hiperlipemias. El uso de modelos y software ... -
Development and Maintenance of the Brain’s Immune Toolkit: Microglia and Non-Parenchymal Brain Macrophages
(Wiley, 2018-06)Microglia and non-parenchymal macrophages located in the perivascular space, the meninges and the choroid plexus are independent immune populations that play vital roles in brain development, homeostasis, and tissue healing. ... -
Development and Mechanical Characterization of Ni-Cr Alloy Foam Using Ultrasonic-Assisted Electroplating Coating Technique
(MDPI, 2023-05-28)Metal foams and alloy foams are a novel class of engineering materials and have numerous applications because of their properties such as high energy absorption, light weight and high compressive strength. In the present ... -
Development and Optimization of Freeze-Dried Eye Drops Derived from Plasma Rich in Growth Factors Technology
(Association for Research in Vision and Ophthalmology, 2020-06)Purpose: To investigate whether plasma rich in growth factors (PRGF) eye drops maintain their biological potential after a freeze drying process. The addition of a lyopro-tectant like trehalose was also evaluated. Methods: ... -
Development and Participation: Whose Participation? A Critical Analysis of the UNDP’s Participatory Research Methods
(Springer Nature, 2020-05-20)Participatory development became a new development orthodoxy during the early 1990s. However, many researchers have criticised that its implementation often fails to live up to its original transformative roots. Since 1992, ... -
Development and Validation of a Frequency Domain Based Methodology for the Preliminary Design of Floating Offshore Wind Semi-Submersible Platforms
(2023-12-12)Through this Thesis, a novel methodology for the preliminary design of floating offshore wind substructures has been developed. The main advantage is the significantly higher efficient, in terms of computational cost, ... -
Development and validation of a new multiplex for upgrading Y-STRs population databases from 12 to 23 markers and its forensic casework application.
(Nature, 2022-12)Y chromosomal short tandem repeats (Y-STRs) are used in forensic investigations as a useful complementary tool to autosomal markers. The ongoing development of new kits with an increasing number of markers makes it necessary ... -
Development and validation of prediction models for complex sampling data
(2024-03-08)Complex survey data are becoming increasingly well-known among researchers from different fields,including social and health sciences. This type of data is obtained by sampling the target populationthrough a complex sampling ... -
Development of a cartilage tissue engineering construct based on hASCs spheroids differentiated under hypoxia in a chitosan/chitin nanocrystals 3D scaffold.
(2019-01-14)The generation of a cartilage tissue engineering (TE) construct is currently a viable strategy for the treatment of osteoarthritis. Such construct requires a biomaterial with optimal properties, including biocompatibility, ... -
Development of a data-driven ageing model for Li-ion batteries: a nonparametric approach to learn from real operation data
(2021-01-25)Li-ioizko bateriek beren hasierako gaitasunak galtzen dituzte denboraren poderioz, baita erabilpen baldintzen arabera ere. Horrek Li-ioizko baterietan oinarrituriko sistemen errentagarritasuna kolokan ezartzen du. Ondorioz, ... -
Development of a deep learning system for hummed melody identification for BertsoBot
(2020-10-09)The system introduced in this work tries to solve the problem of melody classification. The proposed approach is based on extracting the spectrogram of the audio of each melody and then using deep supervised learning ...