Now showing items 1-20 of 142

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      25-Hydroxyvitamin D Concentrations and In Vivo Insulin Sensitivity and b-Cell Function Relative to Insulin Sensitivity in Black and White Youth 

      Rajakumar, Kumaravel; De las Heras Montero, Javier Adolfo; Lee, SoJung; Holick, Michel F.; Arslanian, Silva A. (American Diabetes Association, 2012-03)
      OBJECTIVE To examine the relationships between plasma 25-hydroxyvitamin D [25(OH)D] and in vivo insulin sensitivity and β-cell function relative to insulin sensitivity, disposition index (DI), in black and white ...
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      25-Hydroxyvitamin D in Obese Youth Across theSpectrumofGlucose Tolerance From Normal to Prediabetes to Type 2 Diabetes 

      De las Heras Montero, Javier Adolfo; Rajakumar, Kumaravel; Lee, SoJung; Bacha, Fida; Holick, Michel F.; Arslanian, Silva A. (American Diabetes Association, 2013-07)
      OBJECTIVE To 1) determine if plasma 25-hydroxyvitamin D (25[OH]D) concentrations differ among obese youth with normal glucose tolerance (NGT) versus prediabetes versus type 2 diabetes and 2) assess the relationships ...
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      A Comprehensive Study of Vesicular and Non-Vesicular miRNAs from a Volume of Cerebrospinal Fluid Compatible with Clinical Practice 

      Prieto Fernández, Endika; Aransay Bañares, Ana María; Royo, Félix; González Jiménez, María Esperanza; Lozano, Juan José; Santos Zorrozúa, Borja ORCID; Macías Cámara, Nuria; González López, Monika; Pérez Garay, Raquel; Benito Fernández, Francisco Javier; García-Orad Carles, África ORCID; Falcón Pérez, Juan Manuel (Ivyspring International Publisher, 2019)
      Cerebrospinal fluid (CSF) microRNAs (miRNAs) have emerged as potential biomarkers for minimally invasive diagnosis of central nervous system malignancies. However, despite significant advances in recent years, this field ...
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      A Delphi Process to Optimize Quality and Performance of Drug Evaluation in Neonates 

      Legrand, Frederic; Boulkedid, Rym; Elie, Valery; Leroux, Stephanie; Valls, Elizabeth; Valls Soler, Adolfo; Van den Anker, Johannes N.; Jacqz-Aigrain, Evelyne (Public Library Science, 2014-09-11)
      Background: Neonatal trials remain difficult to conduct for several reasons: in particular the need for study sites to have an existing infrastructure in place, with trained investigators and validated quality procedures ...
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      A Genotyping Method Combining Primer Competition PCR with HRM Analysis to Identify Point Mutations in Duchenne Animal Models 

      Lasa Fernández, Haizpea ORCID; Mosqueira Martín, Laura; Alzualde, Ainhoa; Lasa Elgarresta, Jaione; Vallejo Illarramendi, Ainara (Nature, 2020-10-14)
      Dystrophin-null sapje zebrafish is an excellent model for better understanding the pathological mechanisms underlying Duchenne muscular dystrophy, and it has recently arisen as a powerful tool for high-throughput screening ...
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      A Morphological Method for Ammonia Detection in Liver 

      Gutiérrez de Juan, Virginia; López de Davalillo, Sergio; Fernández Ramos, David; Barbier Torres, Lucía; Zubiete Franco, Imanol; Fernández Tussy, Pablo; Simón Espinosa, Jorge; Lopitz Otsoa, Fernando; De las Heras Montero, Javier Adolfo; Iruzubieta, Paula; Arias Loste, María Teresa; Villa, Erica; Crespo, Javier; Andrade, Raúl; Lucena, M. Isabel; Varela Rey, Marta; Lu, Shelly C.; Mato, José M.; Cardoso Delgado, Teresa de Jesús; Martínez Chantar, María Luz ORCID (Public Library Science, 2017-03-20)
      Hyperammonemia is a metabolic condition characterized by elevated levels of ammonia and a common event in acute liver injury/ failure and chronic liver disease. Even though hepatic ammonia levels are potential predictive ...
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      A Novel Noninvasive Method Based on Salivary Inflammatory Biomarkers for the Screening of Celiac Disease 

      Sebastián de la Cruz, Maialen ORCID; Olazagoitia Garmendia, Ane; Huerta Madrigal, Alain; García Etxebarria, Koldo; Mendoza Gómez, Luis Manuel; Fernández Jiménez, Nora ORCID; García Casales, Zuriñe; De la Calle Navarro, E.; Calvo, A. E.; Legarda Tamara, María; Tutau Gómez, Carlos; Irastorza Terradillos, Iñaki Xarles ORCID; Bujanda Fernández de Pierola, Luis ORCID; Bilbao Catalá, José Ramón; Castellanos Rubio, Ainara (Elsevier, 2021)
      ...
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      A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis 

      Sarasola, Esther; Rodríguez Pérez, José Antonio ORCID; Garrote Llanos, María Isabel; Arístegui Fernández, Javier; García-Barcina, María J. (BioMed Central, 2011-06-27)
      Background: Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive genetic disease characterized by the lack of reaction to noxious stimuli and anhidrosis. It is caused by mutations in the ...
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      A Three-Protein Panel to Support the Diagnosis of Sepsis in Children 

      Pilar Orive, Francisco Javier; Astigarraga Aguirre, María Iciar; Azkargorta, Mikel; Elortza, Felix; García Obregón, Susana (MDPI, 2022-03-12)
      Sepsis is a syndrome without a standard validated diagnostic test. Early recognition is crucial. Serum proteome analysis in children with sepsis may identify new biomarkers. This study aimed to find suitable blood biomarkers ...
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      Accuracy in Copy Number Calling by qPCR and PRT : A Matter of DNA 

      Fernández-Jiménez, Nora; Castellanos Rubio, Ainara; Plaza-Izurieta, Leticia; Gutiérrez, Galder; Irastorza Terradillos, Iñaki Xarles ORCID; Castaño González, Luis Antonio ORCID; Vitoria Cormenzana, Juan Carlos; Bilbao Catalá, José Ramón (Public Library of Science, 2011-12-13)
      The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the ...
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      Acidosis tubular renal distal hereditaria: correlación genotípica, evolución a largo plazo y nuevas perspectivas terapéuticas 

      Gómez Conde, Sara; García Castaño, Alejandro; Aguirre, Mireia; Herrero Goñi, María; Gondra Sangroniz, Leire; Castaño González, Luis Antonio ORCID; Madariaga Domínguez, Leire ORCID (Elsevier, 2021-07)
      [ES] La acidosis tubular renal distal (ATRD) es una enfermedad rara que se debe al fallo del proceso normal de acidificación de la orina a nivel tubular distal y colector. Se caracteriza por una acidosis metabólica ...
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      Addition of terlipressin to initial volume resuscitation in a pediatric model of hemorrhagic shock improves hemodynamics and cerebral perfusion 

      Gil Antón, Javier; Mielgo, Victoria; Rey Santano, María Carmen; Galbarriatu, Lara; Santos, Carlos; Unceta Suárez, María; López Fernández, Yolanda; Redondo, Silvia; Morteruel, Elvira (Public Library Science, 2020-07-02)
      Hemorrhagic shock is one of the leading causes of mortality and morbidity in pediatric trauma. Current treatment based on volume resuscitation is associated to adverse effects, and it has been proposed that vasopressors ...
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      Alveolar nitric oxide and its role in pediatric asthma control assessment 

      Sardón Prado, Olaia; Corcuera Elosegui, Paula; Aldasoro, Ane; Korta Murua, José Javier; Mintegui, Javier; Emparanza Knörr, José Ignacio; González Pérez-Yarza, Eduardo ORCID (Biomed Central, 2014-08-04)
      Resumen Background: Nitric oxide can be measured at multiple flow rates to determine proximal (maximum airway nitric oxide flux; Jaw(NO)) and distal inflammation (alveolar nitric oxide concentration; CA(NO)). The main ...
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      Ambient air pollution and thyroid function in Spanish adults. A nationwide population-based study (Di@bet.es study) 

      Valdés, Sergio; Doulatram Gamgaram, Viyey; Maldonado Araque, Cristina; Lago Sampedro, Ana; García Escobar, Eva; García Serrano, Sara; García Vivanco, Marta; Garrido, Juan Luis; Theobald, Mark Richard; Gil, Victoria; Martín Llorente, Fernando; Ocón, Pilar; Calle Pascual, Alfonso; Castaño González, Luis Antonio ORCID; Delgado, Elías; Menéndez Torre, ‪Edelmiro; Franch Nadal, Josep; Gaztambide Sáenz, María Sonia; Girbes, Joan; Chaves, Felipe J.; Galán García, José Luis; Aguilera Venegas, Gabriel; Gutiérrez Repiso, Carolina; Fernández García, José Carlos; Colomo, Natalia; Soriguer, Federico; García Fuentes, Eduardo; Rojo Martínez, Gemma (BMC, 2022)
      Background Recent reports have suggested that air pollution may impact thyroid function, although the evidence is still scarce and inconclusive. In this study we evaluated the association of exposure to air pollutants to ...
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      Análisis del perfil inflamatorio, clínico y nutricional de la enfermedad celiaca al diagnóstico y tras la implantación de la dieta sin gluten. 

      Díez Bayona, Victoria (2021-07-14)
      Con el objetivo principal de analizar el perfil clínico, genético, inflamatorio y nutricional en los pacientes pediátricos con enfermedad celiaca al diagnóstico y durante el primer año tras la implantación de la dieta sin ...
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      Antibiotic Use in Febrile Children Presenting to the Emergency Department: a Systematic Review 

      Van De Voort, Elles; Mintegi Raso, Santiago ORCID; Gervaix, Alain; Moll, Henriette A.; Oostenbrink, Rianne (Frontiers Media SA, 2018-10-08)
      Introduction: While fever is the main complaint among pediatric emergency services and high antibiotic prescription are observed, only a few studies have been published addressing this subject. Therefore this systematic ...
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      Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation? 

      ISAAC Phase Three Study Group; González Díaz, Carlos; Pérez-Yarza Pérez-Irezabal, Gorka ORCID (Wiley, 2019-04)
      Background: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) measured the global prevalence of symptoms of asthma in children. We undertook comprehensive analyses addressing risk factors ...
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      Asma en los centros escolares e impacto de una intervención educativa en los profesores 

      Korta Murua, José Javier (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitateko Argitalpen Zerbitzua, 2014-05-06)
      Estudio observacional, transversal y descriptivo en el que se ha evaluado el grado de conocimientos que sobre asma tienen los profesores(n=743), sus creencias y actitudes, fuentes de información y los recursos disponibles ...
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      Association between long term exposure to particulate matter and incident hypertension in Spain 

      Doulatram Gamgaram, Viyey; Valdés, Sergio; Maldonado Araque, Cristina; Lago Sampedro, Ana; Badía Guillén, Rocío; García Escobar, Eva; García Serrano, Sara; García Vivanco, Marta; Garrido, Juan Luis; Theobald, Mark Richard; Gil, Victoria; Martín Llorente, Fernando; Calle Pascual, Alfonso; Bordiú, Elena; Castaño González, Luis Antonio ORCID; Delgado, Elías; Franch Nadal, Josep; Chaves, Felipe J.; Montanya, Eduard; Galán García, José Luis; Aguilera Venegas, Gabriel; Soriguer, Federico; Rojo Martínez, Gemma (Nature Research, 2021-10-05)
      [EN]Exposure to air particulate matter has been linked with hypertension and blood pressure levels. The metabolic risks of air pollution could vary according to the specific characteristics of each area, and has not been ...
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      Bacterial pathogens and antimicrobial resistance in acute otitis media 

      Sánchez Arlegui, Amaia; Del Arco Rodríguez, Jorge; De Velasco Vázquez, Xavier; Gallego Rodrigo, Mikel; Gangoiti, Iker; Mintegi Raso, Santiago ORCID (Elsevier, 2024-03)
      Introduction Recent studies show an increase in the prevalence of Haemophilus influenzae and a decrease in Streptococcus pneumoniae among the bacteria that cause acute otitis media (AOM). The objective of our study was ...