Now showing items 1-20 of 285

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      A preliminary analysis of gait performance of patients with multiple sclerosis using a sensorized crutch tip 

      Sesar Gil, Iñigo ORCID; Zubizarreta Pico, Asier ORCID; Cabanes Axpe, Itziar ORCID; Brull Mesanza, Asier ORCID; Torres Unda, Juan José ORCID; Rodríguez Larrad, Ana ORCID (Elsevier, 2020-07-17)
      The quality of life and functional mobility of patients with Multiple Sclerosis (MS) can significantly improve with exercise and a rehabilitation therapy adjusted to the needs of each patient. The assessment of gait and ...
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      A randomised controlled trial of a program based on the theory of planned behavior to promote fruit and vegetable intake among schoolchildren: PROFRUVE study protocol 

      Arrizabalaga López, María; Rada Fernández de Jauregui, Diego ORCID; Portillo Baquedano, María Puy ORCID; Martínez González, Olalla ORCID; Etaio Alonso, Iñaki ORCID; Mauleón Gómez, José Ramón ORCID; Echevarría Orella, Enrique ORCID; Gómez, E.; Rodríguez Rivera, Víctor Manuel (Biomed Central, 2018-07-04)
      Background: The PROFRUVE study is a controlled intervention based on the Theory of Planned Behavior (TPB), which follows those behavioral theories that have proved to be the most effective at changing infant fruit and ...
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      A Randomized Controlled Trial Protocol to Test The Efficacy of a Dual-TaskMulticomponent Exercise Program in the Attenuation of Frailty in Long-Term Nursing Home Residents: Aging-ONDUAL-TASK Study 

      Rezola Pardo, Chloe ORCID; Arrieta Etxeberria, Haritz ORCID; Gil Orozko, Susana María ORCID; Yanguas Lezaun, José Javier; Iturburu Yarza, Miren; Irazusta Astiazaran, Jon ORCID; Sanz Echevarría, María Begoña; Rodríguez Larrad, Ana ORCID (Springer Nature, 2019-01-08)
      BACKGROUND: The purpose of the Aging-ONDUAL-TASK study is to determine if a supervised dual-task program carried out in long-term nursing homes is able to attenuate frailty in a greater extent than the same multicomponent ...
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      A Review of the Epidemiology, Pathophysiology, and Efficacy of Anti-diabetic Drugs Used in the Treatment of Nonalcoholic Fatty Liver Disease 

      Manka, Paul P.; Kaya, Eda; Canbay, Ali; Syn, Wing-Kin (Springer, 2021-08-19)
      In recent years, epidemiological studies have consistently demonstrated that the coexistence of nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) is strongly associated with increased mortality ...
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      A Three-Protein Panel to Support the Diagnosis of Sepsis in Children 

      Pilar Orive, Francisco Javier; Astigarraga Aguirre, María Iciar; Azkargorta, Mikel; Elortza, Felix; García Obregón, Susana (MDPI, 2022-03-12)
      Sepsis is a syndrome without a standard validated diagnostic test. Early recognition is crucial. Serum proteome analysis in children with sepsis may identify new biomarkers. This study aimed to find suitable blood biomarkers ...
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      A UHPLC-Mass Spectrometry View of Human Melanocytic Cells Uncovers Potential Lipid Biomarkers of Melanoma 

      Pérez Valle, Arantza; Abad García, Beatriz; Fresnedo Aranguren, María Olatz; Barreda Gómez, Gabriel; Aspichueta Celaá, Patricia; Asumendi Mallea, Aintzane ORCID; Astigarraga Arribas, Egoitz; Fernández González, José Andrés ORCID; Boyano López, María Dolores ORCID; Ochoa Olascoaga, Begoña ORCID (MDPI, 2021-10-08)
      Melanoma is the deadliest form of skin cancer due to its ability to colonize distant sites and initiate metastasis. Although these processes largely depend on the lipid-based cell membrane scaffold, our understanding of ...
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      Actividad y expresión de enzimas convertidoras de angiotensina en neoplasias renales 

      Varela González, Pedro (2015-04-29)
      En el presente trabajo de tesis doctoral se realizó un análisis de 3 enzimas convertidoras de angiotensina (ACE, ACE2 y APA) en diferentes histotipos de neoplasias renales. Su objetivo fue conocer la implicación de estas ...
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      Added Sugars and Low- and No-Calorie Sweeteners in a Representative Sample of Food Products Consumed by the Spanish ANIBES Study Population 

      Samaniego Vaesken, María de Lourdes; Ruiz Moreno, Emma; Partearroyo Cediel, Teresa; Aranceta Bartrina, Javier; Gil, Ángel; González Gross, Marcela; Ortega Anta, Rosa María; Serra Majem, Lluís; Varela Moreiras, Gregorio (MDPI, 2018-09-07)
      Low- and no-calorie sweeteners (LNCS), intensely sweet compounds that virtually contain no calories, are used to replace added sugars in food and drinks. Knowledge about different LNCS data in Spanish foods and added sugar ...
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      Adenosine: direct and indirect actions on gastric acid secretion 

      Arin Laquidain, Rosa María Engracia ORCID; Gorostidi, Adriana; Navarro Imaz, Hiart; Rueda Estévez, Yuri ORCID; Fresnedo Aranguren, María Olatz; Ochoa Olascoaga, Begoña ORCID (Frontiers Media, 2017-09-22)
      Composed by a molecule of adenine and a molecule of ribose, adenosine is a paradigm of recyclable nucleoside with a multiplicity of functions that occupies a privileged position in the metabolic and regulatory contexts. ...
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      Adiponectin, leptin, and IGF-1 are useful diagnostic and stratification biomarkers of NAFLD 

      Marques, Vanda; Afonso, Marta Bento; Bierig, Nina; Duarte-Ramos, Filipa; Santos Laso, Álvaro; Jiménez Agüero, Raúl; Eizaguirre Letamendia, Emma; Bujanda Fernández de Pierola, Luis ORCID; Pareja Megía, María J.; Luís, Rita; Costa, Adília; Machado, Mariana Verdelho; Alonso, Cristina; Arretxe Oliden, Enara; Alustiza Echeberria, José María; Krawczyk, Marcin; Lammert, Frank; Tiniakos, Dina G.; Flehmig, Bertram; Cortez-Pinto, Helena; Bañales Asurmendi, Jesús María ORCID; Castro, Rui E.; Normann, Andrea; Rodrigues, Cecilia M. P. (Frontiers Media, 2021-06-23)
      [EN] Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to evaluate the role of circulating adiponectin, ...
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      Adult and Developing Zebrafish as Suitable Models for Cardiac Electrophysiology and Pathology in Research and Industry 

      Echeazarra Escudero, Leire ORCID; Hortigón Vinagre, María Pura; Casis Sáenz, Oscar ORCID; Gallego Muñoz, Mónica ORCID (Frontiers Media, 2021-01-13)
      The electrophysiological behavior of the zebrafish heart is very similar to that of the human heart. In fact, most of the genes that codify the channels and regulatory proteins required for human cardiac function have their ...
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      Allostatic hypermetabolic response in PGC1 alpha/beta heterozygote mouse despite mitochondrial defects 

      Rodriguez- Cuenca, Sergio; Lelliot, Christopher J.; Campbell, Mark; Peddinti, Gopal; Martínez Uña, María Teresa; Ingvorsen, Camilla; Dias, Ana Rita; Relat, Joana; Mora, Silvia; Hyötyläinen, Tuulia; Zorzano, Antonio; Oreši, Matej; Bjursell, Mikael; Bohlooly- Y, Mohammad; Lindén, Daniel; Vidal- Puig, Antonio (Wiley, 2021-09)
      Aging, obesity, and insulin resistance are associated with low levels of PGC1 alpha and PGC1 beta coactivators and defective mitochondrial function. We studied mice deficient for PGC1 alpha and PGC1 beta [double heterozygous ...
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      Alteraciones en la actividad enzimática de peptidasas en líquido folicular humano 

      Roméu Périz, Carolina (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitateko Argitalpen Zerbitzua, 2014-06-20)
      En nuestro país existe más de un 15% de parejas en edad reproductiva que padece problemas de fertilidad, el desarrollo y avance de los tratamientos de reproducción asistida está ayudando a que dichas parejas alcancen su ...
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      Alteración de vías moleculares y respuesta clínica en los tumores de cabeza y cuello tratados con terapia biológica con anticuerpos anti-EGFR 

      Díaz de Corcuera Frutos, Isabela (2017-07-20)
      El cáncer de cabeza y cuello es un término que engloba enfermedades que crecen en los senos paranasales, la cavidad oral, nasal, faringe y laringe. A pe¬sar de que el 90% comparten el origen epidermoide con características ...
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      Altered expression of fibroblast activation protein-α (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases 

      Solano Iturri, Jon Danel; Beitia Loinaz, Maider; Errarte Yarza, Peio; Calvete Candenas, Julio; Etxezarraga Zuluaga, María Carmen; Loizate Totoricagüena, Alberto; Echevarría Orella, Enrique ORCID; Badiola Echaburu, Iker ORCID; Larrinaga Embeita, Gorka ORCID (Impact Journals, 2020-06-15)
      Colorectal cancer (CRC) is a major health problem in elderly people because of its high incidence and high mortality rate. Despite early screening programs, more than half of CRC patients are diagnosed at advanced stages. ...
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      Altered glutamyl-aminopeptidase activity and expression in renal neoplasms 

      Blanco Criado, Lorena; Sanz Echevarría, María Begoña; Pérez Urzelai, Itxaro ORCID; Sánchez Fernández, Clara Eugenia; Cándenas, María Luz; Pinto, Francisco M.; Gil Goicouría, Francisco Javier ORCID; Casis Sáenz, Luis ORCID; López Fernández de Villaverde, José Ignacio ORCID; Larrinaga Embeita, Gorka ORCID (Biomed Central, 2014-05-30)
      Background: Advances in the knowledge of renal neoplasms have demonstrated the implication of several proteases in their genesis, growth and dissemination. Glutamyl-aminopeptidase (GAP) (EC. 3.4.11.7) is a zinc metallopeptidase ...
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      Altered Tissue and Plasma Levels of Fibroblast Activation Protein-α (FAP) in Renal Tumours 

      Solano Iturri, Jon Danel; Errarte Yarza, Peio; Etxezarraga Zuluaga, María Carmen; Echevarría Orella, Enrique ORCID; Angulo, Javier; López Fernández de Villaverde, José Ignacio ORCID; Larrinaga Embeita, Gorka ORCID (MDPI, 2020-10-16)
      (1) Background: Renal cell carcinoma (RCC) is a heterogeneous and complex disease with only partial response to therapy, high incidence of metastasis and recurrences, and scarce reliable biomarkers indicative of progression ...
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      An Epilepsy-Causing Mutation Leads to Co-Translational Misfolding of the Kv7.2 Channel 

      Urrutia Iñiguez, Janire ORCID; Aguado Martínez, Alejandra; Gomis Pérez, Carolina; Muguruza Montero, Arantza ORCID; Rodríguez Ballesteros, Oscar; Zhang, Jiaren; Núñez Viadero, Eider ORCID; Malo de la Fuente, Covadonga; Chung, Hee Jung; Leonardo Liceranzu, Aritz ORCID; Bergara Jauregui, Aitor; Villarroel Muñoz, Álvaro (Springer, 2021-05-21)
      BACKGROUND: The amino acid sequence of proteins generally carries all the necessary information for acquisition of native conformations, but the vectorial nature of translation can additionally determine the folding outcome. ...
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      An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer 

      Gerovska, Daniela; Larrinaga Embeita, Gorka ORCID; Solano Iturri, Jon Danel; Márquez Clavijo, Joana ORCID; García Gallastegui, Patricia ORCID; Khatib, Abdel Majid; Poschmann, Gereon; Stühler, Kai; Armesto, María; Lawrie, Charles; Badiola Echaburu, Iker ORCID; Araúzo Bravo, Marcos J. (MDPI, 2020-08-22)
      (1) Background & Aims: The roles of different cells in the tumor microenvironment (TME) are critical to the metastatic process. The phenotypic transformation of the liver cells is one of the most important stages of the ...
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      An Overground Robotic Gait Training Program for People With Multiple Sclerosis: A Protocol for a Randomized Clinical Trial 

      Berriozabalgoitia, Rakel ORCID; Sanz Echevarría, María Begoña; Fraile Bermúdez, Ana Belén ORCID; Otxoa, Erika; Yeregui Prieto, Izaskun ORCID; Bidaurrazaga López de Letona, Iraia ORCID; Duñabeitia Usategui, Iratxe ORCID; Rodríguez-Antigüedad Zarranz, Alfredo; Domercq García, María; Irazusta Astiazaran, Jon ORCID; Rodríguez Larrad, Ana ORCID (Frontiers Media, 2020)
      Maintaining the ability to walk is one of the significant challenges in people with multiple sclerosis (MS) for keeping a good quality of life as the disease and the aging process progresses. Overground robotic (OR) wearable ...