Now showing items 1-20 of 42

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      A Delphi Process to Optimize Quality and Performance of Drug Evaluation in Neonates 

      Legrand, Frederic; Boulkedid, Rym; Elie, Valery; Leroux, Stephanie; Valls, Elizabeth; Valls Soler, Adolfo; Van den Anker, Johannes N.; Jacqz-Aigrain, Evelyne (Public Library Science, 2014-09-11)
      Background: Neonatal trials remain difficult to conduct for several reasons: in particular the need for study sites to have an existing infrastructure in place, with trained investigators and validated quality procedures ...
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      A Morphological Method for Ammonia Detection in Liver 

      Gutiérrez de Juan, Virginia; López de Davalillo, Sergio; Fernández Ramos, David; Barbier Torres, Lucía; Zubiete Franco, Imanol; Fernández Tussy, Pablo; Simon Espinosa, Jorge; Lopitz Otsoa, Fernando; De las Heras Montero, Javier Adolfo; Iruzubieta, Paula; Arias Loste, María Teresa; Villa, Erica; Crespo, Javier; Andrade, Raúl; Lucena, M. Isabel; Varela Rey, Marta; Lu, Shelly C.; Mato, José M.; Cardoso Delgado, Teresa de Jesús; Martínez Chantar, María Luz (Public Library Science, 2017-03-20)
      Hyperammonemia is a metabolic condition characterized by elevated levels of ammonia and a common event in acute liver injury/ failure and chronic liver disease. Even though hepatic ammonia levels are potential predictive ...
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      A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis 

      Sarasola, Esther; Rodríguez Pérez, José Antonio; Garrote Llanos, María Isabel; Arístegui Fernández, Javier; García-Barcina, María J. (BioMed Central, 2011-06-27)
      Background: Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive genetic disease characterized by the lack of reaction to noxious stimuli and anhidrosis. It is caused by mutations in the ...
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      Accuracy in Copy Number Calling by qPCR and PRT : A Matter of DNA 

      Fernández-Jiménez, Nora; Castellanos Rubio, Ainara; Plaza-Izurieta, Leticia; Gutiérrez, Galder; Irastorza Terradillos, Iñaki Xarles; Castaño González, Luis Antonio; Vitoria Cormenzana, Juan Carlos; Bilbao Catalá, José Ramón (Public Library of Science, 2011-12-13)
      The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the ...
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      Alveolar nitric oxide and its role in pediatric asthma control assessment 

      Sardón Prado, Olaia; Corcuera, Paula; Aldasoro, Ane; Korta Murua, José Javier; Mintegui, Javier; Emparanza, José I; González Pérez-Yarza, Eduardo (Biomed Central, 2014-08-04)
      Resumen Background: Nitric oxide can be measured at multiple flow rates to determine proximal (maximum airway nitric oxide flux; Jaw(NO)) and distal inflammation (alveolar nitric oxide concentration; CA(NO)). The main ...
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      Antibiotic Use in Febrile Children Presenting to the Emergency Department: a Systematic Review 

      Van De Voort, Elles; Mintegi Raso, Santiago; Gervaix, Alain; Moll, Henriette A.; Oostenbrink, Rianne (Frontiers Media SA, 2018-10-08)
      Introduction: While fever is the main complaint among pediatric emergency services and high antibiotic prescription are observed, only a few studies have been published addressing this subject. Therefore this systematic ...
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      Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation? 

      ISAAC Phase Three Study Group; González Díaz, Carlos; Pérez-Yarza Pérez-Irezabal, Gorka (Wiley, 2019-04)
      Background: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) measured the global prevalence of symptoms of asthma in children. We undertook comprehensive analyses addressing risk factors ...
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      Asma en los centros escolares e impacto de una intervención educativa en los profesores 

      Korta Murua, José Javier (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitateko Argitalpen Zerbitzua, 2014-05-06)
      Estudio observacional, transversal y descriptivo en el que se ha evaluado el grado de conocimientos que sobre asma tienen los profesores(n=743), sus creencias y actitudes, fuentes de información y los recursos disponibles ...
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      Celiac disease in the Mediterranean area 

      Tucci, Francesca; Astarita, Luca; Abkari, Abdelhak; Abu-Zekry, Mona; Attard, Thomas; Ben Hariz, Mongi; Bilbao Catalá, José Ramón; Boudraa, Ghazalia; Boukthir, Samir; Costa, Stefano; Djurisic, Veselinka; Hugot, Jean-Pierre; Irastorza Terradillos, Iñaki Xarles; Kansu, Aydan; Kolacek, Sanja; Magazzu, Giuseppe; Micetic-Turk, Dusanka; Misak, Zrinjka; Roma, Eleftheria; Rossi, Pasqualino; Terzic, Selma; Velmishi, Virtut; Arcidiaco, Carmela; Auricchio, Renata; Greco, Luigi; (BioMed Central, 2014-02)
      Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe ...
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      Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy 

      Axpe Iza, Eneko; López Euba, Tamara; Castellanos Rubio, Ainara; Mérida Sanz, David; García Martínez, José Angel; Plaza-Izurieta, Leticia; Fernández-Jiménez, Nora; Plazaola Muguruza, Fernando; Bilbao Catalá, José Ramón (Public Library of Science, 2014-01-02)
      Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ...
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      Dobutamine in Paediatric Population: A Systematic Review in Juvenile Animal Models 

      Mielgo, Victoria; Valls Soler, Adolfo; Rey Santano, María Carmen (Public Library Science, 2014-04-22)
      Objective: Although dobutamine is widely used in neonatal clinical practice, the evidence for its use in this specific population is not clear. We conducted a systematic review of the use of dobutamine in juvenile animals ...
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      Dynamics of Streptococcus pneumoniae Serotypes Causing Acute Otitis Media Isolated from Children with Spontaneous Middle-Ear Drainage over a 12-Year Period (1999–2010) in a Region of Northern Spain 

      Alonso, Marta; Marimón, José M.; Ercibengoa, María; González Pérez-Yarza, Eduardo; Pérez Trallero, Emilio (Public Library of Science, 2013-01-22)
      The aim of this study was to determine the serotype and clonal distribution of pneumococci causing acute otitis media (AOM) and their relationship with recurrences and mixed infections with other microorganisms under the ...
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      Fatty acid composition of skeletal muscle and adipose tissue in Spanish infants and children 

      Sanjurjo Crespo, Pablo Gabriel; Aldámiz Echevarría, Luis; Prado, Carmen; Azcona, Isabel; Elorz Lambarri, Javier; Prieto, José A.; Ruiz Sanz, José Ignacio; Rodríguez Soriano, Juan (Cambridge University Press, 2006-01)
      There is a relationship between the fatty acid profile in skeletal muscle phospholipids and peripheral resistance to insulin in adults, but similar data have not been reported in infancy and childhood. The objective of ...
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      Genetics of Type III Bartter Syndrome in Spain, Proposed Diagnostic Algorithm 

      García Castaño, Alejandro; Pérez de Nanclares, Gustavo; Madariaga Domínguez, Leire; Aguirre, Mireia; Madrid, Alvaro; Nadal, Inmaculada; Navarro, Mercedes; Lucas, Elena; Fijo, Julia; Espino, Mar; Espitaletta, Zilac; Castaño González, Luis Antonio; Ariceta, Gema; RenalTube Group (Public Library of Science, 2013-09-18)
      The p.Ala204Thr mutation (exon 7) of the CLCNKB gene is a "founder" mutation that causes most of type III Bartter syndrome cases in Spain. We performed genetic analysis of the CLCNKB gene, which encodes for the chloride ...
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      Hospitalizaciones infantiles asociadas a infección por virus de la gripe en 6 ciudades de España (2014-2016) 

      Arístegui Fernández, Javier; González Pérez-Yarza, Eduardo; Mellado Peña, María José; Rodrigo Gonzalo de Liria, Carlos; Hernández Sampelayo, Teresa; García García, Juan José; Ruiz Contreras, Jesús; Moreno Pérez, David; Garrote Llanos, Elisa; Ramos Amador, José Tomás; Cilla Eguiluz, Carlos Gustavo; Méndez Hernández, María; HOSPIGRIP (Doyma, 2018-02)
      Introduction: There are only a limited number of studies on the impact of influenza in the Spanish child population. The present work intends to increase this knowledge by studying some key aspects, such as the incidence ...
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      Identificación de lactantes menores de 90 días con fiebre sin foco y bajo riesgo de infección bacteriana invasiva. 

      Gómez Cortés, Borja (2019-06-11)
      El lactante menor de 90 días con fiebre sin foco presenta un mayor riesgo de infección bacteriana que loslactantes mayores de esa edad. Esto justifica la existencia de protocolos de manejo específicos para estesubgrupo de ...
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      Identificación de un panel de marcadores proteicos en la fase inicial de la sepsis y su validación en una cohorte de pacientes pediátricos con sepsis grave. 

      Pilar Orive, Francisco javier (2019-04-08)
      La sepsis se define como una disfunción orgánica potencialmente mortal producida por una respuesta desregulada del huésped a la infección. En ella, la respuesta inmune iniciada por el patógeno invasor no va a permitir que ...
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      Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients 

      Garcia-Obregon, Susana; Azkargorta, Mikel; Seijas, Iratxe; Pilar-Orive, Javier; Borrego, Francisco; Elortza, Felix; Boyano López, María Dolores; Astigarraga Aguirre, María Iciar (Elsevier, 2018-08)
      Background: Sepsis is a life-threatening illness with a challenging diagnosis. Current serum biomarkers are not sensitive enough for diagnosis. With the aim of finding proteins associated with sepsis, serum protein profile ...
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      Impacto de una unidad de observación en un servicio de urgencias de pediatría de un hospital europeo de tercer nivel. 

      Martínez Más, Roser (2019-06-06)
      Introducción: Las Unidades de Observación (UO) integradas en los servicios de urgencias pediátricos (SUP) son unidades de estancia corta creadas con el fin de facilitar un manejo ambulatorio de ciertos pacientes tras unas ...
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      Involvement of SNPs in miR-3117 and miR-3689d2 in Childhood Acute Lymphoblastic Leukemia Risk 

      Gutiérrez Camino, Ángela; Martín Guerrero, Idoia; Dolzan, Vita; Jazbec, Janez; Carbone Bañeres, Ana; García de Andoin Barandiaran, Nagore; Sastre, Ana; Astigarraga, Itziar; Navajas Gutiérrez, Aurora; García-Orad Carles, África (Board, 2018-04-01)
      Acute lymphoblastic leukemia (ALL) is the most common cancer in children. Numerous studies have shown that microRNAs (miRNAs) could play a role in this disease. Nowadays, more than 2500 miRNAs have been described, that ...