Now showing items 1-20 of 68

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      A Comprehensive Study of Vesicular and Non-Vesicular miRNAs from a Volume of Cerebrospinal Fluid Compatible with Clinical Practice 

      Prieto Fernández, Endika; Aransay Bañares, Ana María; Royo, Félix; González Jiménez, María Esperanza; Lozano, Juan José; Santos Zorrozúa, Borja; Macías Cámara, Nuria; González López, Monika; Pérez Garay, Raquel; Benito Fernández, Francisco Javier; García Orad, África; Falcón Pérez, Juan Manuel (Ivyspring International Publisher, 2019)
      Cerebrospinal fluid (CSF) microRNAs (miRNAs) have emerged as potential biomarkers for minimally invasive diagnosis of central nervous system malignancies. However, despite significant advances in recent years, this field ...
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      A Delphi Process to Optimize Quality and Performance of Drug Evaluation in Neonates 

      Legrand, Frederic; Boulkedid, Rym; Elie, Valery; Leroux, Stephanie; Valls, Elizabeth; Valls Soler, Adolfo; Van den Anker, Johannes N.; Jacqz-Aigrain, Evelyne (Public Library Science, 2014-09-11)
      Background: Neonatal trials remain difficult to conduct for several reasons: in particular the need for study sites to have an existing infrastructure in place, with trained investigators and validated quality procedures ...
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      A Genotyping Method Combining Primer Competition PCR with HRM Analysis to Identify Point Mutations in Duchenne Animal Models 

      Lasa Fernández, Haizpea; Mosqueira Martín, Laura; Alzualde, Ainhoa; Lasa Elgarresta, Jaione; Vallejo Illaramendi, Ainara (Nature, 2020-10-14)
      Dystrophin-null sapje zebrafish is an excellent model for better understanding the pathological mechanisms underlying Duchenne muscular dystrophy, and it has recently arisen as a powerful tool for high-throughput screening ...
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      A Morphological Method for Ammonia Detection in Liver 

      Gutiérrez de Juan, Virginia; López de Davalillo, Sergio; Fernández Ramos, David; Barbier Torres, Lucía; Zubiete Franco, Imanol; Fernández Tussy, Pablo; Simon Espinosa, Jorge; Lopitz Otsoa, Fernando; De las Heras Montero, Javier Adolfo; Iruzubieta, Paula; Arias Loste, María Teresa; Villa, Erica; Crespo, Javier; Andrade, Raúl; Lucena, M. Isabel; Varela Rey, Marta; Lu, Shelly C.; Mato, José M.; Cardoso Delgado, Teresa de Jesús; Martínez Chantar, María Luz (Public Library Science, 2017-03-20)
      Hyperammonemia is a metabolic condition characterized by elevated levels of ammonia and a common event in acute liver injury/ failure and chronic liver disease. Even though hepatic ammonia levels are potential predictive ...
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      A short in-frame deletion in NTRK1 tyrosine kinase domain caused by a novel splice site mutation in a patient with congenital insensitivity to pain with anhidrosis 

      Sarasola, Esther; Rodríguez Pérez, José Antonio; Garrote Llanos, María Isabel; Arístegui Fernández, Javier; García-Barcina, María J. (BioMed Central, 2011-06-27)
      Background: Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive genetic disease characterized by the lack of reaction to noxious stimuli and anhidrosis. It is caused by mutations in the ...
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      Accuracy in Copy Number Calling by qPCR and PRT : A Matter of DNA 

      Fernández-Jiménez, Nora; Castellanos Rubio, Ainara; Plaza-Izurieta, Leticia; Gutiérrez, Galder; Irastorza Terradillos, Iñaki Xarles; Castaño González, Luis Antonio; Vitoria Cormenzana, Juan Carlos; Bilbao Catalá, José Ramón (Public Library of Science, 2011-12-13)
      The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the ...
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      Addition of terlipressin to initial volume resuscitation in a pediatric model of hemorrhagic shock improves hemodynamics and cerebral perfusion 

      Gil Antón, Javier; Mielgo, Victoria; Rey Santano, María Carmen; Galbarriatu, Lara; Santos, Carlos; Unceta, María; López Fernández, Yolanda; Redondo, Silvia; Morteruel, Elvira (Public Library Science, 2020-07-02)
      Hemorrhagic shock is one of the leading causes of mortality and morbidity in pediatric trauma. Current treatment based on volume resuscitation is associated to adverse effects, and it has been proposed that vasopressors ...
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      Alveolar nitric oxide and its role in pediatric asthma control assessment 

      Sardón Prado, Olaia; Corcuera, Paula; Aldasoro, Ane; Korta Murua, José Javier; Mintegui, Javier; Emparanza, José I; González Pérez-Yarza, Eduardo (Biomed Central, 2014-08-04)
      Resumen Background: Nitric oxide can be measured at multiple flow rates to determine proximal (maximum airway nitric oxide flux; Jaw(NO)) and distal inflammation (alveolar nitric oxide concentration; CA(NO)). The main ...
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      Antibiotic Use in Febrile Children Presenting to the Emergency Department: a Systematic Review 

      Van De Voort, Elles; Mintegi Raso, Santiago; Gervaix, Alain; Moll, Henriette A.; Oostenbrink, Rianne (Frontiers Media SA, 2018-10-08)
      Introduction: While fever is the main complaint among pediatric emergency services and high antibiotic prescription are observed, only a few studies have been published addressing this subject. Therefore this systematic ...
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      Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation? 

      ISAAC Phase Three Study Group; González Díaz, Carlos; Pérez-Yarza Pérez-Irezabal, Gorka (Wiley, 2019-04)
      Background: Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) measured the global prevalence of symptoms of asthma in children. We undertook comprehensive analyses addressing risk factors ...
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      Asma en los centros escolares e impacto de una intervención educativa en los profesores 

      Korta Murua, José Javier (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitateko Argitalpen Zerbitzua, 2014-05-06)
      Estudio observacional, transversal y descriptivo en el que se ha evaluado el grado de conocimientos que sobre asma tienen los profesores(n=743), sus creencias y actitudes, fuentes de información y los recursos disponibles ...
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      Calcium Mechanisms in Limb-Girdle Muscular Dystrophy with CAPN3 Mutations 

      Lasa Elgarresta, Jaione; Mosqueira Martín, Laura; Naldaiz Gastesi, Neia; Sáenz Peña, Amets; López de Munain Arregui, Adolfo José; Vallejo Illaramendi, Ainara (MDPI, 2019-09-02)
      Limb-girdle muscular dystrophy recessive 1 (LGMDR1), previously known as LGMD2A, is a rare disease caused by mutations in the CAPN3 gene. It is characterized by progressive weakness of shoulder, pelvic, and proximal limb ...
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      Calendario de vacunaciones de la Asociación Española de Pediatría: recomendaciones 2020 

      Álvarez García, Francisco José; Cilleruelo Ortega, María José; Álvarez Aldeán, Javier; Garcés Sánchez, María; García Sánchez, Nuria; Garrote Llanos, Elisa; Hernández Merino, Ángel; Iofrío de Arce, Antonio; Merino Moína, Manuel; Montesdeoca Melián, Abián; Navarro Gómez, María Luisa; Ruiz Contreras, Jesús; Asociación Española de Pediatría (CAV-AEP) (Doyma, 2020-01)
      El CAV-AEP publica anualmente el calendario de vacunaciones que estima idóneo para los niños residentes en España, teniendo en cuenta la evidencia científica disponible. Se mantiene el esquema 2 + 1 (2, 4 y 11 meses) ...
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      Calendario de vacunaciones de la Asociación Española de Pediatría: recomendaciones 2021 

      Álvarez García, Francisco José; Cilleruelo Ortega, María José; Álvarez Aldeáne, Javier; Garcés Sánchez, María; García Sánchez, Nuria; Garrote Llanos, Elisa; Hernández Merino, Ángel; Iofrío de Arce, Antonio; Montesdeoca Melián, Abián; Navarro Gómez, María Luisa; Ruiz Contreras, Jesús; Comité Asesor de Vacunas de la Asociación Española de Pediatría (Asociación Española de Pediatría, 2021-01)
      The CAV-AEP annually publishes the immunisation schedule considered optimal for all children and adolescent resident in Spain, taking into account the available evidence. The 2+1 schedule is recommended (2, 4, and 11 months) ...
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      Celiac disease in the Mediterranean area 

      Tucci, Francesca; Astarita, Luca; Abkari, Abdelhak; Abu-Zekry, Mona; Attard, Thomas; Ben Hariz, Mongi; Bilbao Catalá, José Ramón; Boudraa, Ghazalia; Boukthir, Samir; Costa, Stefano; Djurisic, Veselinka; Hugot, Jean-Pierre; Irastorza Terradillos, Iñaki Xarles; Kansu, Aydan; Kolacek, Sanja; Magazzu, Giuseppe; Micetic-Turk, Dusanka; Misak, Zrinjka; Roma, Eleftheria; Rossi, Pasqualino; Terzic, Selma; Velmishi, Virtut; Arcidiaco, Carmela; Auricchio, Renata; Greco, Luigi; (BioMed Central, 2014-02)
      Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe ...
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      Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy 

      Axpe Iza, Eneko; López Euba, Tamara; Castellanos Rubio, Ainara; Mérida Sanz, David; García Martínez, José Angel; Plaza-Izurieta, Leticia; Fernández-Jiménez, Nora; Plazaola Muguruza, Fernando; Bilbao Catalá, José Ramón (Public Library of Science, 2014-01-02)
      Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ...
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      Dobutamine in Paediatric Population: A Systematic Review in Juvenile Animal Models 

      Mielgo, Victoria; Valls Soler, Adolfo; Rey Santano, María Carmen (Public Library Science, 2014-04-22)
      Objective: Although dobutamine is widely used in neonatal clinical practice, the evidence for its use in this specific population is not clear. We conducted a systematic review of the use of dobutamine in juvenile animals ...
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      Dynamics of Streptococcus pneumoniae Serotypes Causing Acute Otitis Media Isolated from Children with Spontaneous Middle-Ear Drainage over a 12-Year Period (1999–2010) in a Region of Northern Spain 

      Alonso, Marta; Marimón Ortiz de Zarate, José María; Ercibengoa, María; González Pérez-Yarza, Eduardo; Pérez Trallero, Emilio (Public Library of Science, 2013-01-22)
      The aim of this study was to determine the serotype and clonal distribution of pneumococci causing acute otitis media (AOM) and their relationship with recurrences and mixed infections with other microorganisms under the ...
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      Ekografia klinikoaren erabilera besaurreko urruneko hereneko hausturen diagnostikorako pediatriako larrialdietan 

      Galletebeitia Laka, Iratxe (2020-12-14)
      El dolor de muñeca secundario a traumatismo o caída es uno de los principales motivos de consulta en Servicios de Urgencias Pediátricas (SUP). En un 25-30% de los casos se identifica fractura del tercio distal del antebrazo. ...
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      ¿Es la transmisión vertical de Chlamydia trachomatis un problema poco reconocido en España? 

      Piñeiro Vázquez, Luis Darío; Korta Murua, José Javier; López Cuesta, Sheila; Lasa, Izaskun; Cilla Eguiluz, Carlos Gustavo (Doyma, 2019-06)
      La infección por Chlamydia trachomatis es un importante problema de salud pública mundial y la principal causa bacteriana de infecciones de transmisión sexual. La infección puede transmitirse a través del canal del parto, ...