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      Identification of Androgen Receptor Metabolic Correlome Reveals the Repression of Ceramide Kinase by Androgens 

      Camacho Soguero, Laura; Zabala Letona, Amaia; Cortázar, Ana Rosa; Astobiza, Ianire; Domínguez Herrera, Asier; Ercilla, Amaia; Crespo, Jana; Viera, Cristina; Fernández-Ruiz, Sonia; Martinez-Gonzalez, Ainara; Torrano Moya, Verónica; Martín-Martín, Natalia; Gómez Muñoz, Antonio; Carracedo Pérez, Arkaitz ORCID (MDPI, 2021-08-26)
      Prostate cancer (PCa) is one of the most prevalent cancers in men. Androgen receptor signaling plays a major role in this disease, and androgen deprivation therapy is a common therapeutic strategy in recurrent disease. ...
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      PI3K-regulated Glycine N-methyltransferase is required for the development of prostate cancer 

      Zabala Letona, Amaia; Arruabarrena Aristorena, Amaia; Fernández Ruiz, Sonia; Viera, Cristina; Carlevaris, Onintza; Ercilla Eguiarte, Amaia; Mendizabal, Isabel; Martín Mateos, Teresa; Macchia, Alice; Camacho Soguero, Laura; Pujana Vaquerizo, Mikel; Sánchez Mosquera, Pilar; Torrano Moya, Verónica; Martín Martín, Natalia; Zuñiga García, Patricia; Castillo Martín, Mireia; Ugalde Olano, Aitziber; Loizaga Iriarte, Ana; Unda Urzaiz, Jesús Miguel; Mato, José M.; Berra Ramírez, Miren Edurne; Martínez Chantar, María Luz ORCID; Carracedo Pérez, Arkaitz ORCID (Springer Nature, 2022-02)
      [EN] Glycine N-Methyltransferase (GNMT) is a metabolic enzyme that integrates metabolism and epigenetic regulation. The product of GNMT, sarcosine, has been proposed as a prostate cancer biomarker. This enzyme is predominantly ...