BackExaminar OpenAire por departamento (eus.) "Kimika organikoa I"
Now showing items 1-12 of 12
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alpha-Branched Ketone Dienolates: Base-Catalyzed Generation and Regio- and Enantioselective Addition Reactions
(Wiley-VCH, 2019-05-14)In this study, the unique capacity of bifunctional Brønsted bases to generate α-branched ketone dienolates and control both site- and stereoselectivity of their addition reactions to representative classes of carbon ... -
An umpolung strategy to react catalytic enols with nucleophiles
(Nature, 2019-11-20)The selective synthesis of a-functionalized ketones with two similar enolizable positions can be accomplished using allylic alcohols and iridium(III) catalysts. A formal 1,3-hydrogen shift on allylic alcohols generates ... -
Bicolour fluorescent molecular sensor for cations: design and experimental validation
; Rivilla de la Cruz, Iván
; ; ; Cossío Mora, Fernando Pedro (Royal Society of Chemistry, 2021-07-02)
Molecular entities whose fluorescence spectra are different when they bind metal cations are termed bicolour fluorescent molecular sensors. The basic design criteria of this kind of compound are presented and the different ... -
Boosting background suppression in the NEXT experiment through Richardson-Lucy deconvolution
The NEXT collaboration; Almazán, H.; Aparicio Gil, Borja; Aranburu Leiva, Ane Izaskun; Benlloch-Rodríguez, J.M.; Cossío Mora, Fernando Pedro; Ferrario, P.; Generowicz, J.; Gómez Cadenas, Juan J.; Herrero, P.; Martínez-Vara, M.; Monrabal, Francesc; Oblak, E.; Odriozola Gimeno, Mikel; Ripoll, L.; Rivilla de la Cruz, Iván ; Rogero Blanco, Celia; Romeo, B.; Romo-Luque, C.; Santos, F.P.; Dos Santos, J.M.F.; Sorel, M.; Stanford, C.; Teixeira, J.M.R.; Thapa, P.; Toledo, J.F.; Torrent, J.; Usón, A.; Veloso, J.F.C.A.; Vuong, T.T.; Webb, R.; White, J.T.; Woodruff, K.; Yahlali, N. (Springer, 2021-07-21)
Next-generation neutrinoless double beta decay experiments aim for half-life sensitivities of similar to 10(27) yr, requiring suppressing backgrounds to < 1 count/tonne/yr. For this, any extra background rejection handle, ... -
Brønsted Base Catalyzed One-Pot Synthesis od Stereodefined Six-Member Carbocycles Featuring Transient Trienolates and a Key Intramolecular 1,6-Addition
(Wiley-VCH, 2019-07-31)Acatalyst-driven one-pot reaction sequence is developed for the enantio- and diastereoselective synthesis of tetrasubstituted cyclohexenes from simple unsaturated ketones or thioesters.The method involves atertiary ... -
Catalysis of a 1,3-dipolar reaction by distorted DNA incorporating a heterobimetallic platinum(II) and copper(II) complex
Rivilla de la Cruz, Iván; ; Schäfer, Thomas ; ; ; ; Aboudzadeh, Ali ; ; ; Cossío Mora, Fernando Pedro (Royal Society of Chemistry, 2017-08-11)
A novel catalytic system based on covalently modified DNA is described. This catalyst promotes 1,3-dipolar reactions between azomethine ylides and maleimides. The catalytic system is based on the distortion of the double ... -
Iron-Catalyzed Direct α-Arylation of Ethers with Azoles
Correa Navarro, Arkaitz; ; (Royal Society of Chemistry, 2015-07-14)
The direct α-arylation of cyclic and acyclic ethers with azoles has been achieved, which features a novel iron-catalyzed cross-dehydrogenative coupling (CDC) process. This practical oxidative method allowed the efficient ... -
Manganese-Catalyzed Multicomponent Synthesis of Tetrasubstituted Propargylamines: System Development and Theoretical Study
(Wiley-VCH, 2020-07-20)The importance of multicomponent reactions as an efficient tool in organic synthesis is widely recognized, as the need for sustainable, practical, atom- and step-economic methodologies is becoming a crucial concept in ... -
Rigidochromism by imide functionalisation of an aminomaleimide fluorophore
(Royal Society Of Chemistry, 2021-08-21)Fluorescent dyes that exhibit high solid state quantum yields and sensitivity to the mechanical properties of their local environment are useful for a wide variety of applications, but are limited in chemical diversity. ... -
Synthesis of Indenes by the Tandem Gold(I)-Catalyzed Claisen Rearrangement/Hydroarylation Reaction of Propargyl Vinyl Ethers
(ACS, 2019-05-06)The tandem gold(I)-catalyzed propargyl Claisen rearrangement/hydroarylation reaction of suitable propargyl vinyl ethers, followed by in situ reduction of the resulting carbonyl group, provides functionalized indenes in ... -
Towards a more precise therapy in cancer: Exploring epigenetic complexity
Cossío Mora, Fernando Pedro; Esteller, Manel; Berdasco, María (Elsevier, 2020-08)
A plethora of preclinical evidences suggests that pharmacological targeting of epigenetic dysregulation is a potent strategy to combat human diseases. Nevertheless, the implementation of epidrugs in clinical practice is ... -
Unprecedented Multicomponent Organocatalytic Synthesis of Propargylic Esters via CO2 Activation
(Wiley‐VCH, 2019-02-19)An efficient and straightforward organocatalytic method for the direct, multicomponent carboxylation of terminal alkynes with CO2 and organochlorides, towards propargylic esters, is reported for the first time. ...