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Role of Furin in Colon Cancer Stem Cells Malignant Phenotype and Expression of LGR5 and NANOG in KRAS and BRAF-Mutated Colon Tumors
(MDPI, 2022-02-25)
Proprotein convertases or PCs are known to regulate the malignant phenotype of colon cancer cells by different mechanisms, but their effects on cancer stem cells (CSCs) have been less widely investigated. Here, we report ...
Non-invasive diagnosis of viability in seeds and lichens by infrared thermography under controlled environmental conditions
(BMC, 2019-12)
Background: Non-invasive procedures for the diagnosis of viability of plant or fungal tissues would be valuable for scientific, industrial and biomonitoring purposes. Previous studies showed that infrared thermography (IRT) ...
Pollen Geochronology from the Atlantic Coast of the United States during the Last 500 Years
(MDPI, 2021-01-31)
Building robust age–depth models to understand climatic and geologic histories from coastal sedimentary archives often requires composite chronologies consisting of multi-proxy age markers. Pollen chronohorizons derived ...
Growth and resilience responses of Scots pine to extreme droughts across Europe depend on predrought growth conditions
(GLOBAL CHANGE BIOLOGY, 2020)
Global climate change is expected to further raise the frequency and severity of extreme events, such as droughts. The effects of extreme droughts on trees are difficult to disentangle given the inherent complexity of ...
Age of Information of a Server with Energy Requirements
(PeerJ, 2021-03-01)
We investigate a system with Poisson arrivals to two queues. One queue stores the status updates of the process of interest (or data packets) and the other handles the energy that is required to deliver the updates to the ...
An EU comparative analysis of the regulation of clinical trials supervisory bodies in the aftermath of Regulation 536/2014
(Kluwer Law International BV, The Netherlands, 2020-06)
The new EU regulation on clinical trials is intended to promote a greater level of harmonization of European Union rules in this area. However, it does not elaborate a common normative framework regarding the functioning ...
Challenges for Digitalisation in Building Renovation to Enhance the Efficiency of the Process: A Spanish Case Study
(MDPI, 2021-11-03)
Although construction is one of the largest industries in the world, it is one of the least digitised and its productivity is still very low. Excesses of time and cost are common and are even more accentuated for building ...
Structural Health Monitoring Using Ultrasonic Guided-Waves and the Degree of Health Index
(MDPI, 2021-02-02)
This paper proposes a new damage index named degree of health (DoH) to efficiently tackle structural damage monitoring in real-time. As a key contribution, the proposed index relies on a pattern matching methodology that ...
An Empirical Study on Transmission Beamforming for Ultrasonic Guided-Wave Based Structural Health Monitoring
(MDPI, 2020-03-06)
The development of reliable structural health monitoring techniques is enabling a healthy transition from preventive to condition-based maintenance, hence leading to safer and more efficient operation of different industries. ...
A flexible strain-responsive sensor fabricated from a biocompatible electronic ink via an additive-manufacturing process
(2021-08)
Biosensor technologies are of great interest for applications in wearable electronics, soft robotics and implantable biomedical devices. To accelerate the adoption of electronics for chronic recording of physiological ...