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Tailored gelatin-based three-dimensional sysems for bone tissue engineering.
(2019-12-17)
The current Doctoral Thesis is focused on the development of three-dimensional systems for bone tissue engineering purposes. Gelatin was chosen as the main material to manufacture scaffolds capable for serving as both ...
Bioanthropology of obesity in a population of the Autonomus Community of the Basque Country
(2017-09-18)
Obesity has become a major health concern worldwide due to its increasing prevalence and its detrimental health impact. The overarching aim of the present thesis was to study the aetiology of obesity from anthropological, ...
Changes in lipids and formation of derived compounds during fish cooking and in vitro gastrointestinal digestion of edible oils, model systems and processed fish meat
(2017-03-07)
En la presente tesis doctoral se plantearon cuatro objetivos principales. En el primer objetivo, se estudiaron los cambios provocados por el proceso de cocinado en los lípidos y/o perfil volátil del pescado mediante ...
Development and characterization of non-viral vectors based on cationic niosomes to address cystic fibrosis disease by gene therapy approach
(2022-03-17)
Gene therapy is based on the delivery of exogenous genetic material into target cells to modulate theexpression of an altered genome in order to treat a specific disease. Lipid nanocarriers, such as niosomesbased on cationic ...
Development of new child-friendly methods to measure food-evoked emotions holistically
(2022-07-29)
Before conducting a child-centered study, the selection of the methodology to use is of special importance since it should be adapted to their cognitive, physical, and social stage of development. On this regard, researchers ...
Antibiotic-loaded nanstructured lipid carriers (NLCs) for multiresistant respiratory tract and wound infections.
(2020-12-10)
La resistencia a los antibióticos (AMR) es un problema grave que debe abordarse lo antes posible. La colistina y la amikacina representan unos de los pocos antibióticos eficaces contra las infecciones de las bacterias ...
Biofunctionalization of alginate microcapsules: advances in cell-based drug delivery systems
(2015-09-16)
En la tesis titulada Biofunctionalization of alginate microcapsules: advances in cell-based drug delivery systems se han realizado tres trajajos experimentales basados en microcápsulas de alginato modificadas con diferentes ...
Evaluación clínica y análisis coste-efectividad del envío de mensajes motivacionales como herramienta adyuvante para dejar de fumar.
(2020-11-27)
El tabaquismo constituye la primera causa de morbi-mortalidad evitable a nivel mundial. Es uno de los mayores problemas de salud pública al que se ha tenido que enfrentar lahumanidad, matando hasta la mitad de sus consumidores. ...
Treatment of corneal inflammation by topical gene therapy with non-viral vectors as delivery systems of the interleukin-10 gene
(2020-07-21)
El proceso inflamatorio de la superficie ocular subyace en la base de importantes enfermedades que pueden provocar incluso la pérdida de la visión en los casos más graves. Actualmente, la terapia de elección de la inflamación ...
Development of a stem cells-based gene therapy approach mediated by non-viral vectors with potential clinical applications in regenerative medicine
(2020-12-15)
En la tesis actual, demostramos que los nioplexos DP80 podían transfectar eficientemente célulasmesenquimales MSC D1 con los plásmidos pCMS-EGFP y pUNO1-hBMP7. Sin embargo, se requiere laoptimización del proceso de formulación ...