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Enols and Allylic Alcohols as Building Blocks in Synthetic Organic Chemistry. Experimental and Theoretical Studies.
(2022-10-21)
The presen thesis describes computational and experimental studies used to drive the reactivity o allylic and enol subtrates towards new transformations. These synthetic methods give access to a number of organic molecules ...
Design and Chemical Synthesis of Fluorescent Bicolor Indicators for the Detection of Neutrinoless Double Beta Decay of 136Xe
(2022-11-11)
La observación de la desintegración beta doble sin neutrinos (¿¿¿¿) demostraría que el neutrino es una partícula de Majorana, es decir, su propia antipartícula. Este proceso de desintegración sólo es posible en algunos ...
Development of novel hybrid phosphorated quinoline derivatives as topoisomerase 1B inhibitors with antiproliferative activity
(2022-07-07)
El presente trabajo de Tesis Doctoral recopila la síntesis y evaluación biológica de nuevos derivados híbridos de quinolinas fosforadas como inhibidores de topoisomerasa 1B humana (hTOP1B) con actividad antiproliferativa. ...
Short Peptide-Derived Bifunctional Brønsted Base Catalysts in Asymmetric Michael Reactions
(2022-04-01)
Peptide catalysis has proven to be an effective tool for the synthesis of
enantiomerically enriched compounds with synthetic applications or that are precursors
of molecules with biological and pharmacological interest. ...