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Erresberatrola eta kertzetinaren metabolitoen efektuak 3T3-L1 adipozitoen adipogenesian eta triglizeridoen metabolismoan, hala onola jatorrizko konposatuen efektuekin konparatzea
(2019-07-05)
El Resveratrol y la Quercetina son dos ingredientes funcionales a los que se les ha atribuido efecto reductor de grasa en diversos experimentos in vivo e in vitro. Sin embargo, su rápido metabolismo hace que solo una pequeña ...
Novel nanostructured lipid carriers based on Ω-3 polyunsaturated fatty acids and TAT peptide for neurodegenerative disease treatment
(2020-12-14)
Neurodegenerative diseases (NDs) are an accelerating global problem, but we still lack routes to develop effective therapeutics. In this quest, it is crucial to identify novel drug candidates or drug carriers, which cross ...
Development of novel therapeutic approaches to promote the healing of chronic wounds
(2018-12-04)
En esta tesis se han desarrollado diferentes formulaciones terapéuticas para la cicatrización de heridas crónicas, ya que éstas son una patología en auge, por el gran aumento de los factores que participan en la cronificación ...
Gluten gabeko dieta: Euskal Autonomia Erkidegoko pertsona zeliakoen dieta ohiturak
(2019-07-15)
Gaixotasun zeliakoa (GZa) oinarri immunologikoa duen patologia bat da, glutena hartzeak sortzen duena genetikoki joera duten pertsonetan. Glutena prolaminen taldeko proteina da, zenbait zerealen hazietan dagoena. Datuen ...
Bioinspired three-dimensional multifunctional systems to enhance the therapeutic potential of mesenchymal stromal cells
(2019-12-16)
Mesenchymal stromal cells (MSCs) present the ability to secrete important immunomodulatory factors, and therefore, hold great potential for the treatment of multiple inflammatory and immune disorders. However, for the ...
Tailored gelatin-based three-dimensional sysems for bone tissue engineering.
(2019-12-17)
The current Doctoral Thesis is focused on the development of three-dimensional systems for bone tissue engineering purposes. Gelatin was chosen as the main material to manufacture scaffolds capable for serving as both ...
Risk factors of overweight/obesity-related lifestyles, particularly those associated with diet, in students of the University of the Basque Country UPV/EHU
(2020-09-11)
[EN]Although an energy imbalance over a long period seems to be the main cause of overweight/obesity, this factor is included in a complex biological system that is set within a complex societal framework in which no single ...
Polyplexes based on ultrapure oligochitosans: design, characterization and applications for gene therapy.
(2016-03-02)
Esta tesis doctoral se basa en el uso de oligoquitosanos ultrapuros (UOC) como vectores no-virales para el transporte de genes. El quitosano (Ch) es un polímero natural compuesto de cadenas ß-(1-4) D-glucosamina y ...
On-campus food environment in two European public universities: food purchasing behaviours ,choice determinants and opinions on the food availability among the university community
(2022-02-16)
To date, there are no studies on the food environment (FE) in European universities, that include both external and personal domains. This cross-sectional observational study was designed to assess the FE through both ...
Design and evaluation of nucleic-acid based medicinal products to address corneal inflammation by gene therapy
(2022-03-04)
La suplementación génica consiste en la administración de ácidos nucleicos (ADN o ARNm) para inducir la producción de una proteína terapéutica. En la actualidad, el uso del ARNm se ha extendido debido su alta eficacia, ...