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Now showing items 11-20 of 20
Role of notch and wnt signaling in metabolic and epigenetic reprogramming of human dental pulp stem cells (DPSCs)
(2019-03-01)
Las Células Stem de Pulpa Dental (DPSCs; en inglés) son células madre extraídas de la pulpa dental de terceros molares de pacientes. Presentan unas propiedades que las convierte en un recurso especialmente interesante para ...
Development of a cartilage tissue engineering construct based on hASCs spheroids differentiated under hypoxia in a chitosan/chitin nanocrystals 3D scaffold.
(2019-01-14)
The generation of a cartilage tissue engineering (TE) construct is currently a viable strategy for the treatment of osteoarthritis. Such construct requires a biomaterial with optimal properties, including biocompatibility, ...
Neuroprotection of retinal ganglion cells by Müller Glia in vitro in health and disease
(2019-10-07)
Las células ganglionares de la retina (RGCs) son las únicas neuronas aferentes de la retina y transmiten la información visual al cerebro a través de sus axones, que forman el nervio óptico y su muerte causa una ceguera ...
Development of new methods in biomedical engineering for brain connectivity biomarkers in epilepsy and other pathological conditions
(2018-05-07)
The aim of this thesis is to humbly explore the application of diverse methodologies and theories comingfrom Computer Sciences, Mathematics and Physics in the field of neurosciences, with an special focus onneurodegenerative ...
Natural Killer (NK) cells and cancer: nanotechnology-based new methods development for the enhancement of antitumor immunotherapy efficacy
(2022-10-06)
[EU]Jakina denez, NK (ingelesetik ¿natural killer¿) eta T zelulak interleukinekin estimulatzeak, hala nolahobetu egiten ditu haien funtzio efektiboak, minbiziaren erauzteko estrategia izanik. Tesi honetannanoformulazio ...
Role of RKIP and Pirin in the malignant progression of cutaneous melanoma. New diagnosis and prognosis biomarkers
(2022-09-23)
Melanoma is an extremely lethal skin cancer that arises as a result of the malignant transformation of melanocytes. The incidence of this pathology worldwide has increased in the last 30 years in greater proportion than ...
Ocoxin osagarri naturalaren eragin antitumorala pankreako minbiziko eta kolon-ondesteko minbiziaren metastasi hepatikoko eredu esperimentaletan.
(2020-12-22)
Pankreako minbiziak eta kolon-ondesteko minbiziaren metastasi hepatikoak heriotza ugari eragiten dituzte urtero. Hauek tratatzeko erabiltzen den teknika nagusienetariko bat kimioterapia da, zeinak pazienteengan zehar-efektu ...
Arming NK cells with chimeric antigen receptors (CARs) for treatment of refractory and/or relapsed hematological cancers: preclinical study to determine the best cell source.
(2020-02-10)
Acute Lymphoblastic Leukemia (ALL) and Chronic Lymphocytic Leukemia (CLL) are the most prevalent hematological cancers in children and elder patients respectively. Sometimes, standard treatments are not enough for curing ...
Characterization of a mouse model of autism. Focus on the excitatory/inhibitory and dopaminergic pathways
(2023-10-27)
El Trastorno del Espectro Autista (TEA) es una condición del neurodesarrollo que presenta diversos síntomas, entre los que destacan los déficits en comunicación y comportamiento social y la presencia de movimientos ...
Analysis of different strategies for in vitro diagnosis of human humoral biomarkers based on solid support immobilization
(2023-11-03)
The study of biomarkers and their detection in human fluids represents one of the best ways to improve the diagnosis and prevention of diseases. The use of human fluids for biomarker analysis can facilitate a friendly and ...