Browsing Artículos, Comunicaciones, Libros by Author "Egaña-Huguet, Jon"
Now showing items 1-6 of 6
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Endocannabinoid long-term depression revealed at medial perforant path excitatory synapses in the dentate gyrus
Peñasco Iglesias, Sara; Rico Barrio, Irantzu; Puente Bustinza, Nagore; Gómez Urquijo, Sonia María
; Fontaine, Christine J.; Egaña Huguet, Jon; Achicallende Urcaregui, Svein
; Ramos Uriarte, Almudena
; Reguero Acebal, Leire
; Elezgarai Gabantxo, Izaskun
; Nahirney, Patrick C.; Christie, Brian R.; Grandes Moreno, Pedro Rolando
(Elsevier, 2019-04-22)
The endocannabinoid system modulates synaptic plasticity in the hippocampus, but a link between long-term synaptic plasticity and the type 1 cannabinoid (CB1) receptor at medial perforant path (MPP) synapses remains elusive. ... -
Environmental Enrichment Rescues Endocannabinoid-Dependent Synaptic Plasticity Lost in Young Adult Male Mice after Ethanol Exposure during Adolescence
Rico Barrio, Irantzu; Peñasco Iglesias, Sara; Lecumberri Odriozola, Leire; Serrano Murgia, Maitane; Egaña Huguet, Jon; Mimenza Saiz, Amaia; Soria Gómez, Edgar
; Ramos Uriarte, Almudena
; Buceta Salazar, Ianire
; Gerrikagoitia Marina, Inmaculada
; Mendizabal Zubiaga, Juan Luis
; Elezgarai Gabantxo, Izaskun
; Puente Bustinza, Nagore
; Grandes Moreno, Pedro Rolando
(MDPI, 2021-07-16)
Binge drinking (BD) is a serious health concern in adolescents as high ethanol (EtOH) consumption can have cognitive sequelae later in life. Remarkably, an enriched environment (EE) in adulthood significantly recovers ... -
Lack of the transient receptor potential vanilloid 1 shifts cannabinoid-dependent excitatory synaptic plasticity in the dentate gyrus of the mouse brain hippocampus
Egaña Huguet, Jon; Saumell Esnaola, Miquel; Achicallende Urcaregui, Svein; Soria Gómez, Edgar
; Bonilla del Río, Itziar; García del Caño, Gontzal; Barrondo Lacarra, Sergio
; Sallés Alvira, Joan; Gerrikagoitia Marina, Inmaculada
; Puente Bustinza, Nagore
; Elezgarai Gabantxo, Izaskun
; Grandes Moreno, Pedro Rolando
(Frontiers Media, 2021-07-07)
[EN] The transient receptor potential vanilloid 1 (TRPV1) participates in synaptic functions in the brain. In the dentate gyrus, post-synaptic TRPV1 in the granule cell (GC) dendritic spines mediates a type of long-term ... -
The Absence of the Transient Receptor Potential Vanilloid 1 Directly Impacts on the Expression and Localization of the Endocannabinoid System in the Mouse Hippocampus
Egaña Huguet, Jon; Bonilla del Río, Itziar; Gómez Urquijo, Sonia María; Mimenza Saiz, Amaia; Saumell Esnaola, Miquel; Borrega Román, Leire; García del Caño, Gontzal; Sallés Alvira, Joan; Puente Bustinza, Nagore
; Gerrikagoitia Marina, Inmaculada
; Elezgarai Gabantxo, Izaskun
; Grandes Moreno, Pedro Rolando
(Frontiers Media, 2021-02-22)
The transient receptor potential vanilloid 1 (TRPV1) is a non-selective ligand-gated cation channel involved in synaptic transmission, plasticity, and brain pathology. In the hippocampal dentate gyrus, TRPV1 localizes to ... -
The Endocannabinoid System in Glial Cells and Their Profitable Interactions to Treat Epilepsy: Evidence from Animal Models
Epilepsy is one of the most common neurological conditions. Yearly, five million people are diagnosed with epileptic-related disorders. The neuroprotective and therapeutic effect of (endo)cannabinoid compounds has been ... -
Up-regulation of CB1 Cannabinoid Receptors Located at Glutamatergic Terminals in the Medial Prefrontal Cortex of the Obese Zucker Rat.
Echeazarra, Leyre; Barrondo Lacarra, Sergio; García del Caño, Gontzal; Bonilla del Río, Itziar; Egaña Huguet, Jon; Puente Bustinza, Nagore
; Aretxabala Rodríguez, Xabier; Montaña, Mario; López de Jesús, Maider
; González Burguera, Imanol; Saumell Esnaola, Miquel; Goicolea Altuna, María Aranzazu
; Grandes Moreno, Pedro Rolando
; Sallés Alvira, Joan (Frontiers Media, 2022-10-18)
The present study describes a detailed neuroanatomical distribution map of the cannabinoid type 1 (CB1) receptor, along with the biochemical characterization of the expression and functional coupling to their cognate G i/o ...