Examinar Artículos, Comunicaciones, Libros por departamento (cas.) "Genética, antropología física y fisiología animal"

Now showing items 101-120 of 269

    • Thumbnail

      Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994 

      Jelenkovic Moreno, Aline; Hur, Yoon-M.; Sund, Reijo; Yokoyama, Yoshie; Siribaddana, Sisira H.; Hotopf, Matthew; Sumathipala, Athula; Rijsdijk, Fruhling; Tan, Qihua; Zhang, Dongfeng; Pang, Zengchang; Aaltonen, Sari; Heikkila, Kauko; Öncel, Sevgi Y.; Aliev, Fazil; Rebato, Esther; Tarnoki, Adam D.; Tarnoki, David L.; Christensen, Kaare; Skytthe, Axel; O Kyvik, Kirsten; Silberg, Judy L.; Eaves, Lindon J.; Maes, Hermine H.; Cutler, Tessa L.; Hopper, John L.; Ordoñana Martín, Juan Ramón; Sánchez Romera, Juan Francisco; Colodro Conde, Lucía; Cozen, Wendy; Hwang, Amie E.; Mack, Thomas M.; Sung, Joohon; Song, Yun-Mi; Yang, Sarah; Lee, Kayoung; Franz, Carol E.; Kremen, William S.; Lyons, Michael J.; Busjahn, Andreas; Nelson, Tracy L.; Whitfield, Keith E.; Kandler, Christian; Jang, Kerry L; Gatz, Margaret; Butler, David A.; Stazi, Maria A.; Fagnani, Corrado; D’Ippolito, Cristina; Duncan, Glen E.; Buchwald, Dedra; Derom, Catherine A.; Vlietinck, Robert F.; Loos, Ruth J.F.; Martin, Nicholas G.; Medland, Sarah E.; Montgomery, Grant W.; Jeong, Hoe-Uk; Swan, Gary E.; Krasnow, Ruth; Magnusson, Patrik K.E.; Pedersen, Nancy L.; Dahl-Aslan, Anna K.; McAdams, Tom A.; Eley, Thalia C.; Gregory, Alice M.; Tynelius, Per; Baker, Laura A.; Tuvblad, Catherine; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Lichtenstein, Paul; Spector, Timothy D.; Mangino, Massimo; Lachance, Genevieve; Bartels, Meike; Van Beijsterveldt, Toos C.E.M.; Willemsen, Gonneke; Burt, S. Alexandra; Klump, Kelly L.; Harris, Jennifer R.; Brandt, Ingunn; Nilsen, Thomas Sevenius; Krueger, Robert F.; McGue, Matt; Pahlen, Shandell; Corley, Robin P.; Hjelmborg, Jacob v. B.; Goldberg, Jack H.; Iwatani, Yoshinori; Watanabe, Mikio; Honda, Chika; Inui, Fujio; Rasmussen, Finn; Huibregtse, Brooke M.; Boomsma, Dorret I.; Sørensen, Thorkild I. A.; Kaprio, Jaakko; Silventoinen, Karri (eLife Sciences Publications, 2016-12-14)
      Human height variation is determined by genetic and environmental factors, but it remains unclear whether their influences differ across birth-year cohorts. We conducted an individual-based pooled analysis of 40 twin ...
    • Thumbnail

      Genetic and Environmental Influences on Growth from Late Childhood to Adulthood: A Longitudinal Study of Two Finnish Twin Cohorts 

      Jelenkovic Moreno, Aline; Ortega-Alonso, Alfredo; Rose, Richard J; Kaprio, Jaakko; Rebato Ochoa, Esther Matilde; Silventoinen, Karri (Wiley, 2011-09-29)
      Objectives: Human growth is a complex process that remains insufficiently understood. We aimed to analyze genetic and environmental influences on growth from late childhood to early adulthood. Methods: Two cohorts of ...
    • Thumbnail

      Genetic and environmental influences on height from infancy to early adulthood: An individualbased pooled analysis of 45 twin cohorts 

      Jelenkovic Moreno, Aline; Sund, Reijo; Hur, Yoon-Mi; Yokoyama, Yoshie; Hjelmborg, Jacob v. B.; Möller, Sören; Honda, Chika; Magnusson, Patrik K. E.; Pedersen, Nancy L.; Ooki, Syuichi; Aaltonen, Sari; Stazi, Maria A.; Fagnani, Corrado; D’Ippolito, Cristina; Freitas, Duarte L.; Maia, José Antonio; Ji, Fuling; Ning, Feng; Pang, Zengchang; Rebato Ochoa, Esther Matilde; Busjahn, Andreas; Kandler, Christian; Saudino, Kimberly J.; Jang, Kerry L.; Cozen, Wendy; Hwang, Amie E.; Mack, Thomas M.; Gao, Wenjing; Yu, Canqing; Li, Liming; Corley, Robin P.; Huibregtse, Brooke M.; Derom, Catherine A.; Vlietinck, Robert F.; Loos, Ruth J. F.; Heikkilä, Kauko; Wardle, Jane; Llewellyn, Clare H.; Fisher, Abigail; McAdams, Tom A.; Eley, Thalia C.; Gregory, Alice M.; He, Mingguang; Ding, Xiaohu; Bjerregaard-Andersen, Morten; Beck-Nielsen, Henning; Sodemann, Morten; Tarnoki, Adam D.; Tarnoki, David L.; Knafo-Noam, Ariel; Mankuta, David; Abramson, Lior; Burt, S. Alexandra; Klump, Kelly L.; Silberg, Judy L.; Eaves, Lindon J.; Maes, Hermine H.; Krueger, Robert F.; McGue, Matt; Pahlen, Shandell; Gatz, Margaret; Butler, David A.; Bartels, Meike; Van Beijsterveldt, Toos C.E.M.; Craig, Jeffrey M.; Saffery, Richard; Dubois, Lise; Boivin, Michel; Brendgen, Mara; Dionne, Ginette; Vitaro, Frank; Martin, Nicholas G.; Medland, Sarah E.; Montgomery, Grant W.; Swan, Gary E.; Krasnow, Ruth; Tynelius, Per; Lichtenstein, Paul; Haworth, Claire M.A.; Plomin, Robert; Bayasgalan, Gombojav; Narandalai, Danshiitsoodol; Harden, K. Paige; Tucker-Drob, Elliot M.; Spector, Timothy; Mangino, Massimo; Lachance, Genevieve; Baker, Laura A.; Tuvblad, Catherine; Duncan, Glen E.; Buchwald, Dedra; Willemsen, Gonneke; Skytthe, Axel; Kyvik, Kirsten O.; Christensen, Kaare; Öncel, Sevgi Y.; Aliev, Fazil; Rasmussen, Finn; Goldberg, Jack H.; Sørensen, Thorkild I.A.; Boomsma, Dorret I.; Kaprio, Jaakko; Silventoinen, Karri (Nature Research, 2016-06-23)
      Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ by sex, age and global regions is lacking. We conducted an individual-based ...
    • Thumbnail

      Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education 

      Jelenkovic Moreno, Aline; Sund, Reijo; Yokoyama, Yoshie; Latvala, Antti; Sugawara, Masumi; Tanaka, Mami; Matsumoto, Satoko; Freitas, Duarte L.; Maia, José Antonio; Knafo Noam, Ariel; Mankuta, David; Abramson, Lior; Ji, Fuling; Ning, Feng; Pang, Zengchang; Rebato Ochoa, Esther Matilde; Saudino, Kimberly J.; Cutler, Tessa L.; Hopper, John L.; Ullemar, Vilhelmina; Almqvist, Catarina; Magnusson, Patrik K. E.; Cozen, Wendy; Hwang, Amie E.; Mack, Thomas M.; Nelson, Tracy L.; Whitfield, Keith E.; Sung, Joohon; Kim, Jina; Lee, Jooyeon; Lee, Sooji; Llewellyn, Clare H.; Fisher, Abigail; Medda, Emanuela; Nisticò, Lorenza; Toccaceli, Virgilia; Baker, Laura A.; Tuvblad, Catherine; Corley, Robin P.; Huibregtse, Brooke M.; Derom, Catherine A.; Vlietinck, Robert F.; Loos, Ruth J. F.; Burt, S. Alexandra; Klump, Kelly L.; Silberg, Judy L.; Maes, Hermine H.; Krueger, Robert F.; McGue, Matt; Pahlen, Shandell; Gatz, Margaret; Butler, David A.; Harris, Jennifer R.; Brandt, Ingunn; Nilsen, Thomas S.; Harden, K. Paige; Tucker-Drob, Elliot M.; Franz, Carol E.; Kremen, William S.; Lyons, Michael J.; Lichtenstein, Paul; Bartels, Meike; Van Beijsterveldt, Catharina E. M.; Willemsen, Gonneke; Öncel, Sevgi Y.; Aliev, Fazil; Jeong, Hoe-Uk; Hur, Yoon-Mi; Turkheimer, Eric; Boomsma, Dorret I.; Sørensen, Thorkild I. A.; Kaprio, Jaakko; Silventoinen, Karri (Nature, 2020-05-14)
      Genetic factors explain a major proportion of human height variation, but differences in mean stature have also been found between socio-economic categories suggesting a possible effect of environment. By utilizing a ...
    • Thumbnail

      Genetic and metabolic determinants of methotrexate-induced mucositis in pediatric acute lymphoblastic leukemia 

      den Hoed, M. A.; López López, Elixabet ORCID; Te Winkel, M. L.; Tissing, W.; de Rooij, J. D.; Gutiérrez Camino, Ángela ORCID; García-Orad Carles, África ORCID; den Boer, E.; Pieters, R.; Pluijm, S. M.; de Jonge, R.; van den Heuvel-Eibrink, M. M. (Springer Nature, 2014-11-04)
      Methotrexate (MTX) is an effective and toxic chemotherapeutic drug in the treatment of pediatric acute lymphoblastic leukemia(ALL). In this prospective study, we aimed to identify metabolic and genetic determinants of MTX ...
    • Thumbnail

      Genetic Contribution of Endometriosis to the Risk of Developing Hormone-Related Cancers 

      Rueda Martínez, Aintzane; Garitazelaia González, Aiara; Cilleros Portet, Ariadna ORCID; Marí Alemany, Sergi; Arauzo, Rebeca; De Miguel, Jokin; González García, Bárbara P.; Fernández Jiménez, Nora ORCID; Bilbao Catalá, José Ramón ORCID; García Santisteban, Iraia ORCID (MDPI, 2021-06-04)
      Endometriosis is a common gynecological disorder that has been associated with endometrial, breast and epithelial ovarian cancers in epidemiological studies. Since complex diseases are a result of multiple environmental ...
    • Thumbnail

      Genetic regulation of body size and morphology in children: a twin study of 22 anthropometric traits 

      Silventoinen, Karri; Maia, José Antonio; Li, Weilong; Sund, Reijo; Gouveia, Elvio; Antunes, Antonio; Marques, Gonçalo; Thomis, Martine; Jelenkovic Moreno, Aline; Kaprio, Jaakko; Freitas, Duarte L. (Nature, 2023-03)
      Background Anthropometric measures show high heritability, and genetic correlations have been found between obesity-related traits. However, we lack a comprehensive analysis of the genetic background of human body morphology ...
    • Thumbnail

      Genetic Variants and Hamstring Injury in Soccer: An Association and Validation Study 

      Larruskain Zabala, Jon; Celorrio Herrera, David; Barrio Beraza, Irantzu; Odriozola Martínez, Adrián; Gil Orozko, Susana María ORCID; Fernandez-Lopez, Juan R; Nozal, Raul; Ortuzar Pérez, Isusko; Lekue Gallano, José Antonio ORCID; Aznar, José M. (American College of Sports Medicine, 2018-02)
      Purpose: This study aimed to investigate the association of candidate single nucleotide polymorphisms (SNP) with noncontact hamstring muscle injuries in elite soccer players and to create and validate a model to assess the ...
    • Thumbnail

      Genetic Variants in MiRNA Processing Genes and Pre-MiRNAs Are Associated with the Risk of Chronic Lymphocytic Leukemia 

      Martín Guerrero, Idoia; Gutiérrez Camino, Ángela ORCID; López López, Elixabet ORCID; Bilbao Aldaiturriaga, Nerea; Pombar Gómez, María; Ardanaz, Maite; García-Orad Carles, África ORCID (Public Library Science, 2015-03-20)
      Genome wide association studies (GWAS) have identified several low-penetrance susceptibility alleles in chronic lymphocytic leukemia (CLL). Nevertheless, these studies scarcely study regions that are implicated in non-coding ...
    • Thumbnail

      Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia 

      Karol, S. E.; Larsen, E.; Yang, W.; Cheng, C.; Cao, X.; Ramsey, L. B.; Fernandez, C. A.; McCorkle, J. R.; Paugh, S. W.; Autry, R. J.; López López, Elixabet ORCID; Diouf, B.; Jeha, S.; Pui, C-H.; Raetz, E. A.; Winick, N. J.; Carroll, W. L.; Hunger, S. P.; Loh, M. L.; Devidas, M.; Evans, W. E.; Yang, J. J.; Relling, M. V. (Springer Nature, 2017-01-18)
      The causes of individual relapses in children with acute lymphoblastic leukemia (ALL) remain incompletely understood. We evaluated the contribution of germline genetic factors to relapse in 2225 children treated on Children's ...
    • Thumbnail

      Genome of Pesxtera Muierii skull shows high diversity and low mutational load in pre-glacial Europe 

      Svensson, Emma; Günther, Torsten; Hoischen, Alexander; Hervella Afonso, Montserrat ORCID; Munters, Arielle R.; Ioana, Mihai; Ridiche, Florin; Edlund, Hanna; Van Deuren, Rosanne C.; Soficaru, Andrei; De la Rúa Vaca, Concepción ORCID; Netea, Mihai G.; Jakobsson, Mattias (Elsevier, 2021-07-26)
      Few complete human genomes from the European Early Upper Palaeolithic (EUP) have been sequenced. Using novel sampling and DNA extraction approaches, we sequenced the genome of a woman from "Pesxtera Muierii,"Romania who ...
    • Thumbnail

      Genome of Peștera Muierii skull shows high diversity and low mutational load in pre-glacial Europe 

      Svensson, Emma; Günther, Torsten; Hoischen, Alexander; Hervella Afonso, Montserrat ORCID; Munters, Arielle R.; Ioana, Mihai; Ridiche, Florin; Edlund, Hanna; Van Deuren, Rosanne C.; Soficaru, Andrei Dorian; De la Rúa Vaca, Concepción ORCID; Netea, Mihai G.; Jakobsson, Mattias (Elsevier, 2021-07-26)
      [EN] Few complete human genomes from the European Early Upper Palaeolithic (EUP) have been sequenced. Using novel sampling and DNA extraction approaches, we sequenced the genome of a woman from ‘‘Pesxtera Muierii,’’ ...
    • Thumbnail

      Genomic Selection Signatures In Sheep From The Western Pyrenees 

      Ruiz Larrañaga, Otsanda ORCID; Langa Arranz, Jorge Eliseo ORCID; Rendo Fornet, Fernando ORCID; Manzano Basabe, Carmen ORCID; Iriondo Orensanz, Mikel ORCID; Estomba Recalde, Miren Andone ORCID (Biomed Central, 2018-03-22)
      Background: The current large spectrum of sheep phenotypic diversity results from the combined product of sheep selection for different production traits such as wool, milk and meat, and its natural adaptation to new ...
    • Thumbnail

      Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells 

      Olazagoitia Garmendia, Ane; Zhang, Linda; Mera, Paula; Godbout, Julie K.; Sebastián de la Cruz, Maialen ORCID; García Santisteban, Iraia ORCID; Mendoza Gómez, Luis Manuel; Huerta Madrigal, Alain; Irastorza Terradillos, Iñaki Xarles ORCID; Bhagat, Govind; Green, Peter H.; Herrero, Laura; Serra, Dolors; Rodríguez Pérez, José Antonio ORCID; Verdú, Elena F.; He, Chuan; Bilbao Catalá, José Ramón ORCID; Castellanos Rubio, Ainara (BMJ, 2022-01)
      [EN] Objectives Coeliac disease (CD) is a complex autoimmune disorder that develops in genetically susceptible individuals. Dietary gluten triggers an immune response for which the only available treatment so far is a ...
    • Thumbnail

      Golgi Oncoprotein GOLPH3 Gene Expression is Regulated by Functional E2F and CREB/ATF Promoter Elements 

      Peñalver González, Beatriz ORCID; Vallejo Rodríguez, Jon ORCID; Mentxaka Miranda, Gartze; Fullaondo Elordui-Zapaterieche, Asier ORCID; Iglesias Ara, Ainhoa; Field, Seth J.; Zubiaga Elordieta, Ana María ORCID (MDPI, 2019-03-25)
      The Golgi organelle duplicates its protein and lipid content to segregate evenly between two daughter cells after mitosis. However, how Golgi biogenesis is regulated during interphase remains largely unknown. Here we show ...
    • Thumbnail

      Growth and Physiological Performance in Growth Phenotypes of the Carpet Shell Clam (Ruditapes decussatus) Fed Diets of Variable Lipid/Carbohydrate Ratios 

      Arranz Juárez, Kristina Arantxa; Urruchurtu Gutiérrez, Iñaki ORCID; Martínez Patiño, Dorotea; Navarro Adorno, Enrique (Hindawi, 2023-08-12)
      Mixed suspensions of phytoplankton and yeast cells in different proportions were designed to achieve diets with a range of variation (0.6–2.2) in the ratio of lipid to carbohydrate while maintaining protein content constant. ...
    • Thumbnail

      GSE4-Loaded Nanoparticles a Potential Therapy for Lung Fibrosis that Enhances Pneumocyte Growth, Reduces Apoptosis and DNA Damage 

      Pintado Berninches, Laura; Montes Worboys, Ana; Manguán García, Cristina; García Arias-Salgado, Elena; Serrano, Adela; Fernández Varas, Beatriz; Guerrero López, Rosa; Iarriccio, Laura; Planas Cerezales, Lurdes; Güenechea Amurrio, Guillermo; Egusquiaguirre Martín, Susana Patricia; Hernández Martín, Rosa María ORCID; Igartua Olaechea, Manuela ORCID; Pedraz Muñoz, José Luis ORCID; Cortijo Gimeno, Julio; Sastre Garzón, Leandro; Molina Molina, María; Perona Abellón, Rosario (Wiley, 2021-03)
      Idiopathic pulmonary fibrosis is a lethal lung fibrotic disease, associated with aging with a mean survival of 2-5 years and no curative treatment. The GSE4 peptide is able to rescue cells from senescence, DNA and oxidative ...
    • Thumbnail

      High Expression of Endogenous Retroviral Envelope Gene in the Equine Fetal Part of the Placenta 

      Stefanetti, Valentina; Marenzoni, Maria Luisa; Passamonti, Fabrizio; Cappelli, Katia; García Etxebarria, Koldo; Coletti, Mauro; Capomaccio, Stefano (Public Library Science, 2016-05-13)
      Endogenous retroviruses (ERVs) are proviral phases of exogenous retroviruses that have co-evolved with vertebrate genomes for millions of years. Previous studies have identified the envelope (env) protein genes of retroviral ...
    • Thumbnail

      High frequency of mitochondrial haplogroups H and H2 in medieval individuals from the Cathedral of Santa María (Basque Country). Their contribution to the study of inflammatory arthropathies 

      García Ventades, Nerea ORCID; De la Rúa Vaca, Concepción ORCID; Hervella Afonso, Montserrat ORCID (Elsevier, 2023-02)
      The haplogroup H has been associated with high mitochondrial energy efficiency, which may have favoured survival and reproduction under adverse environmental conditions. On the other hand, it enhances the production of ...
    • Thumbnail

      High Mitochondrial DNA Stability in B-Cell Chronic Lymphocytic Leukemia 

      Cerezo, María; Bandelt, Hans-Jürgen; Martín Guerrero, Idoia; Ardanaz, Maite; Vega, Ana; Carracedo, Angel; García-Orad Carles, África ORCID; Salas, Antonio (Public Library Science, 2009-11-18)
      Background: Chronic Lymphocytic Leukemia (CLL) leads to progressive accumulation of lymphocytes in the blood, bone marrow, and lymphatic tissues. Previous findings have suggested that the mtDNA could play an important role ...