BackBrowsing ACHUCARRO by Author "Tremblay, Marie-Ève"
Now showing items 1-3 of 3
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From the Cajal alumni Achucarro and Rio-Hortega to the rediscovery of never-resting microglia
(Frontiers Research Foundation, 2015-04-14)Under the guidance of Ramon y Cajal, a plethora of students flourished and began to apply his silver impregnation methods to study brain cells other than neurons: the neuroglia. In the first decades of the twentieth century, ... -
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling
Abiega Etxabe, Oihane; Beccari Galeano, Marlene Soledad; Diaz-Aparicio, Irune; Nadjar, Agnes; Layé, Sophie; Leyrolle, Quentin; Gómez-Nicola, Diego; Domercq García, María
; Pérez-Samartín, Alberto; Sánchez-Zafra, Víctor; Paris Guerrero, Ignacio; Valero Gómez-Lobo, Jorge; Savage, Julie C.; Hui, Chin-Wai; Tremblay, Marie-Ève; Deudero, Juan J. P.; Brewster, Amy L.; Anderson, Anne E.; Zaldumbide Dueñas, Laura; Galbarriatu, Lara; Marinas, Ainhoa; Vivanco Ruiz, María del Mar; ; Maletic-Savatic, Mirjana; Encinas Pérez, Juan Manuel; Sierra Saavedra, Amanda (2016)
Phagocytosis by microglia is tightly coupled to apoptosis, swiftly removing apoptotic cells and actively maintaining tissue homeostasis, but the neuronal hyperactivity associated with epilepsy disrupts the ATP gradients ... -
Never-resting microglia: physiological roles in the healthy brain and pathological implications
(Frontiers Research Foundation, 2014-08-15)Microglia are largely known as the major orchestrators of the brain inflammatory response. As such, they have been traditionally studied in various contexts of disease, where their activation has been assumed to induce a ...