ACHUCARRO;;ACHUCARRO: Recent submissions

Now showing items 17-20 of 33

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      Pio del Rio Hortega and the discovery of the oligodendrocytes 

      Pérez Cerdá, Fernando ORCID; Sánchez Gómez, María Victoria ORCID; Matute Almau, Carlos José (Frontiers Research Foundation, 2015-07-07)
      Rio del Rio Hortega (1882-1945) discovered microglia and oligodendrocytes (OLGs), and after Ramon y Cajal, was the most prominent figure of the Spanish school of neurology. He began his scientific career with Nicolas ...
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      Differential Neuroprotective Effects of 5 '-Deoxy-5 '-Methylthioadenosine 

      Moreno, Beatriz; Lopez, Iciar; Fernández-Díez, Begoña; Gottlieb, Miroslav; Matute Almau, Carlos José; Sánchez Gómez, María Victoria ORCID; Domercq García, María ORCID; Giralt, Albert; Alberch, Jordi; Collon, Kevin W.; Zhang, Helen; Parent, Jack M.; Teixido, Meritxell; Giralt, Ernest; Ceña, Valentín; Posadas, Inmaculada; Martínez-Pinilla, Eva; Villoslada, Pablo; Franco, Rafael (Public Library Science, 2014-03-05)
      Background: 5'-deoxy-5'-methylthioadenosine (MTA) is an endogenous compound produced through the metabolism of polyamines. The therapeutic potential of MTA has been assayed mainly in liver diseases and, more recently, in ...
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      CGP37157, an inhibitor of the mitochondrial Na+/Ca2+ exchanger, protects neurons from excitotoxicity by blocking voltage-gated Ca2+ channels 

      Ruiz Núñez, Asier ORCID; Alberdi Alfonso, Elena María ORCID; Matute Almau, Carlos José (Nature Publishing Group, 2014-04)
      Inhibition of the mitochondrial Na+/Ca2+ exchanger (NCLX) by CGP37157 is protective in models of neuronal injury that involve disruption of intracellular Ca2+ homeostasis. However, the Ca2+ signaling pathways and stores ...
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      FTY720 attenuates excitotoxicity and neuroinflammation 

      Cipriani, Raffaela ORCID; Chara Ventura, Juan Carlos; Rodríguez-Antigüedad Zarranz, Alfredo; Matute Almau, Carlos José (BioMed Central, 2015-05-08)
      Background: FTY720 (fingolimod, Gilenya(TM)), a structural analog of sphingosine-1-phosphate (S1P), is the first oral drug approved for treatment the relapsing-remitting form of multiple sclerosis (MS), and its efficacy ...