Now showing items 25-28 of 33

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      Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis 

      Sierra Saavedra, Amanda; Abiega Etxabe, Oihane; Shahraz, Anahita; Neumann, Harald (Frontiers Research Foundation, 2013-01)
      Microglia are the resident brain macrophages and they have been traditionally studied as orchestrators of the brain inflammatory response during infections and disease. In addition, microglia has a more benign, less explored ...
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      1-42 beta-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death 

      Manterola, L.; Hernando Rodríguez, M.; Ruiz Núñez, Asier ORCID; Apraiz, A.; Arrizabalaga Uriarte, Oskar ORCID; Vellon, L.; Alberdi Alfonso, Elena María ORCID; Cavaliere, Fabio; Lacerda, Hadriano M.; Jimenez, S.; Parada, L. A.; Matute Almau, Carlos José; Zugaza Gurruchaga, José Luis ORCID (Nature Publishing Group, 2013-01)
      1-42 beta-Amyloid (A beta(1-42)) peptide is a key molecule involved in the development of Alzheimer's disease. Some of its effects are manifested at the neuronal morphological level. These morphological changes involve ...
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      Contribution of Pannexin1 to Experimental Autoimmune Encephalomyelitis 

      Lutz, Sarah E.; González Fernández, Estibaliz; Chara Ventura, Juan Carlos; Pérez Samartín, Alberto Luis ORCID; Tarassishin, Leonid; Negoro, Hiromitsu; Patel, Naman K.; Suadicani, Sylvia O.; Lee, Sunhee C.; Matute Almau, Carlos José; Scemes, Eliana (Public Library of Science, 2013-06)
      Pannexin1 (Panx1) is a plasma membrane channel permeable to relatively large molecules, such as ATP. In the central nervous system (CNS) Panx1 is found in neurons and glia and in the immune system in macrophages and T-cells. ...
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      Arquitectura subcelular del sistema endocannabinoide en el núcleo ventromedial del hipotálamo de ratón 

      Reguero Acebal, Leire ORCID (2014-01-30)
      El sistema endocannabinoide (eCB) es un complejo sistema endógeno de señalización, que participa en la modulación de la transmisión sináptica en múltiples circuitos cerebrales, incluyendo los que regulan el apetito, ingesta ...