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dc.contributor.advisorCasillas Rubio, Arantza
dc.contributor.advisorPérez Martínez, Alicia
dc.contributor.authorSantiso González, Sara
dc.date.accessioned2019-09-02T09:54:41Z
dc.date.available2019-09-02T09:54:41Z
dc.date.issued2019-06-13
dc.date.submitted2019-06-13
dc.identifier.urihttp://hdl.handle.net/10810/35127
dc.description148 p.es_ES
dc.description.abstractThis work focuses on the automatic extraction of Adverse Drug Reactions (ADRs) in Electronic HealthRecords (EHRs). That is, extracting a response to a medicine which is noxious and unintended and whichoccurs at doses normally used. From Natural Language Processing (NLP) perspective, this wasapproached as a relation extraction task in which the drug is the causative agent of a disease, sign orsymptom, that is, the adverse reaction.ADR extraction from EHRs involves major challenges. First, ADRs are rare events. That is, relationsbetween drugs and diseases found in an EHR are seldom ADRs (are often unrelated or, instead, related astreatment). This implies the inference from samples with skewed class distribution. Second, EHRs arewritten by experts often under time pressure, employing both rich medical jargon together with colloquialexpressions (not always grammatical) and it is not infrequent to find misspells and both standard andnon-standard abbreviations. All this leads to a high lexical variability.We explored several ADR detection algorithms and representations to characterize the ADR candidates.In addition, we have assessed the tolerance of the ADR detection model to external noise such as theincorrect detection of implied medical entities implied in the ADR extraction, i.e. drugs and diseases. Westtled the first steps on ADR extraction in Spanish using a corpus of real EHRs.es_ES
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectartifical intelligencees_ES
dc.subjectcomputational linguisticses_ES
dc.subjectinteligencia artificiales_ES
dc.subjectlingüística computacionales_ES
dc.titleAdverse drug reaction extraction on electronic health records written in Spanishes_ES
dc.typeinfo:eu-repo/semantics/doctoralThesises_ES
dc.rights.holderAtribución 3.0 España*
dc.rights.holder(cc)2019 SARA SANTISO GONZALEZ (cc by 4.0)
dc.identifier.studentID634500es_ES
dc.identifier.projectID17761es_ES
dc.departamentoesLenguajes y sistemas informáticoses_ES
dc.departamentoeuHizkuntza eta sistema informatikoakes_ES


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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España