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dc.contributor.advisorPérez Cerda, Fernando
dc.contributor.authorMatute González, Mario
dc.contributor.otherF. MEDICINA Y ODONTOLOGIA
dc.contributor.otherMEDIKUNTZA ETA ODONTOLOGIA F.
dc.date.accessioned2020-06-03T06:54:17Z
dc.date.available2020-06-03T06:54:17Z
dc.date.issued2020-06-03
dc.identifier.urihttp://hdl.handle.net/10810/43719
dc.description.abstract[EN] Oligodendrocytes build up the myelin sheath that insulates axons and speeds up action potential propagation. Moreover, oligodendroglia also regulates the ionic environment and fuels axons with metabolites to meet their energy demands. In this review, I discuss the mechanisms by which oligodendrocytes and myelin are metabolically coupled to axons, and how they adjust metabolic support to spiking activity. In sum, the major goal of this review is to have a better insight into how axons rely on their myelinating partners for fulfilling energy demands. I propose that this axon-to-myelin interaction can be critical to understand axonal and neuronal damage in neurodegenerative and demyelinating diseases, as well as connectivity alterations in neuropsychiatric disorders.es_ES
dc.language.isoenges_ES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMyelines_ES
dc.subjectoligodendroglia
dc.subjectaxo-myelinic synapse
dc.subjectoligodendrocytes
dc.titleMyelin: more than just an insulatores_ES
dc.typeinfo:eu-repo/semantics/bachelorThesis
dc.date.updated2019-04-11T15:19:49Z
dc.language.rfc3066es
dc.rights.holder© 2019, Mario Matute González
dc.contributor.degreeGrado en Medicina;;Medikuntzako Graduaes_ES
dc.identifier.gaurassign79862-737479


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