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Unraveling the role of astrocytes in the onset and spread of Parkinson's Disease: Important contributors to neurodegeneration.
(2020-02-28)
La enfermedad de Parkinson (EP) se caracteriza principalmente por la presencia de inclusiones citoplasmáticas llamadas cuerpos de Lewy, cuyo principal componente es la ¿-sinucleína y la pérdida de neuronas dopaminérgicas ...
Neurocognitive, social cognitive, and clinical predictors of creativity in schizophrenia
(Pergamon-Elsevier, 2020-10)
Background: Creativity is considered an essential human accomplishment and a key component for daily life problem solving. It has been suggested that impairment in working memory, cognitive flexibility, and theory of mind ...
Cannabinoid Control of Olfactory Processes: The Where Matters
(MDPI, 2020-04-16)
Olfaction has a direct influence on behavior and cognitive processes. There are different neuromodulatory systems in olfactory circuits that control the sensory information flowing through the rest of the brain. The presence ...
Specific Hippocampal Interneurons Shape Consolidation of Recognition Memory
(Cell Press, 2020-08-18)
A complex array of inhibitory interneurons tightly controls hippocampal activity, but how such diversity specifically affects memory processes is not well understood. We find that a small subclass of type 1 cannabinoid ...
Synucleinopathy alters nanoscale organization anddiffusion in the brain extracellular space throughhyaluronan remodeling
(Nature, 2020-07-10)
In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains ...
Special Issue “Olfaction: From Genes to Behavior”
(MDPI, 2020-06-15)
The senses dictate how the brain represents the environment, and this representation is the basis of how we act in the world [...]
Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division
(Frontiers Media, 2020-08-14)
A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable ...
Assessment of Psychiatric Symptomatology in Bilingual Psychotic Patients: A Systematic Review and Meta-Analysis
(MDPI, 2020-06-10)
Language plays an important role in psychiatric conditions. Language disturbances are core symptoms of psychiatric ailments, and language is the main diagnostic tool to assess psychopathological severity. Although the ...
Contribution of P2X4 Receptors to CNS Function and Pathophysiology
(MDPI, 2020-08-03)
The release and extracellular action of ATP are a widespread mechanism for cell-to-cell communication in living organisms through activation of P2X and P2Y receptors expressed at the cell surface of most tissues, including ...
Functional and Metabolic Characterization of Microglia Culture in a Defined Medium
(Frontiers Media, 2020-02-07)
Microglia are the endogenous immune cells of the brain and act as sensor of infection and pathologic injury to the brain, leading to a rapid plastic process of activation that culminates in the endocytosis and phagocytosis ...