Search
Now showing items 171-180 of 185
Phase behaviour of C18-N-acyl sphingolipids, the prevalent species in human brain.
(Elsevier, 2022-11)
Lipidomic analysis of the N-acyl components of sphingolipids in different mammalian tissues had revealed that brain tissue differed from all the other samples in that SM contained mainly C18:0 and C24:1N-acyl chains, and ...
Liquid-crystalline, liquid-ordered, rippled and gel lipid bilayer phases as observed with nile red fluorescence
(Elsevier, 2022-10)
The basic matrix of cellular membranes consists of a double layer (bilayer) of phospholipids. Semisynthetic lipid bilayers are commonly used in biophysical studies of membranes. According to tem-perature and composition, ...
LC3 subfamily in cardiolipin-mediated mitophagy: a comparison of the LC3A, LC3B and LC3C homologs
(Taylor & Francis, 2022-12)
Externalization of the phospholipid cardiolipin (CL) to the outer mitochondrial membrane has been proposed to act as a mitophagy trigger. CL would act as a signal for binding the LC3 macroauto-phagy/autophagy proteins. As ...
Lipid-protein interactions in autophagy: Exploring the role of LC3/GABARAP-family members
(2022-07-19)
La autofagia es una vía de degradación conservada entre los eucariotas caracterizada por la formación de una vesícula de doble membrana (autofagosoma) alrededor de lo que se quiere degradar para su posterior eliminación ...
Patches and Blebs: A Comparative Study of the Composition and Biophysical Properties of Two Plasma Membrane Preparations from CHO Cells
(MDPI, 2020-04-10)
This study was aimed at preparing and characterizing plasma membranes (PM) from Chinese Hamster Ovary (CHO) cells. Two methods of PM preparation were applied, one based on adhering cells to a poly-lysine-coated surface, ...
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope.
(Nature, 2022)
Antibodies against the carboxy-terminal section of the membrane-proximal external region (C-MPER) of the HIV-1 envelope glycoprotein (Env) are considered as nearly pan-neutralizing. Development of vaccines capable of ...
Nucleophosmin interaction with APE1: Insights into DNA repair regulation
(Elsevier, 2020-01-30)
[EN] Nucleophosmin (NPM1), an abundant, nucleolar protein with multiple functions affecting cell homeostasis, has also been recently involved in DNA damage repair. The roles of NPM1 in different repair pathways remain ...
Molecular recognition of the HIV-1 neutralizing MPER epitope reconstituted in membranes. Contribution of lipid composition and transmembrane domain inclusion.
(2022-04-08)
GIBaren gainazalean kokatzen den Env proteina da birusaren infekzioa hasteko gertatu behar den birusaren eta itu zelularen mintzen arteko fusioa eragiten duena eta immunitate sistemarentzako eskuragarri dagoen proteina ...
Descubrimiento de nuevas dianas terapéuticas en cáncer de mama basado en el análisis de metilación del ARNm.
(2022-04-07)
N6-metiladenosina (m6A) es una de las modificaciones más abundante del ARNm presente en los organismos eucariotas. Distintos estudios han revelado que la modificación m6A está involucrada en la regulación de la mayoría de ...
Regulation of macrophage and preadipocyte proliferation and migration by C1P
(2022-03-25)
Chronic inflammatory diseases are the most significant cause of death in the world. Indeed, according to the World Health Organization (WHO), 3 out of 5 people die due to chronic inflammatory diseases such as stroke, chronic ...