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Cells, Materials, and Fabrication Processes for Cardiac Tissue Engineering
(Frontiers Media, 2020-08-11)
Cardiovascular disease is the number one killer worldwide, with myocardial infarction (MI) responsible for approximately 1 in 6 deaths. The lack of endogenous regenerative capacity, added to the deleterious remodelling ...
Plasma Rich in Growth Factors technology: characterization, regulatory framework, current trends and perspectives
(2020-12-18)
La tecnología de plasma rico en factores de crecimiento, PRGF (por sus siglas en inglés, Plasma Rich in Growth Factors) es una terapia biológica autóloga que utiliza los propios componentes de la sangre del paciente como ...
Extraction, Characterization and Incorporation of Hypericum scruglii Extract in Ad Hoc Formulated Phospholipid Vesicles Designed for the Treatment of Skin Diseases Connected with Oxidative Stress
(MDPI, 2020-10-23)
An extract of Hypericum scruglii, an endangered endemic plant of Sardinia (Italy), was prepared and characterized. It was loaded in special phospholipid vesicles, glycerosomes, which were modified by adding maltodextrin ...
Evaluation of Glycerylphytate Crosslinked Semi- and Interpenetrated Polymer Membranes of Hyaluronic Acid and Chitosan for Tissue Engineering
(MDPI, 2020-11-11)
In the present study, semi- and interpenetrated polymer network (IPN) systems based on hyaluronic acid (HA) and chitosan using ionic crosslinking of chitosan with a bioactive crosslinker, glycerylphytate (G1Phy), and UV ...
Encapsulation of Oleuropein in Nanostructured Lipid Carriers: Biocompatibility and Antioxidant Efficacy in Lung Epithelial Cells
(MDPI, 2020-05-06)
Oxidative damage has been linked to a number of diseases. Oleuropein (OLE), a natural occurring polyphenol from olive leaves (Olea europaea L.), is known to be a potent antioxidant compound with inherent instability and ...
Decreased salivary lactoferrin levels are specific to Alzheimer's disease
(Elsevier, 2020-07)
Background: Evidences of infectious pathogens in Alzheimer's disease (AD) brains may suggest a deteriorated innate immune system in AD pathophysiology. We previously demonstrated reduced salivary lactoferrin (Lf) levels, ...
Antibiotic-loaded nanstructured lipid carriers (NLCs) for multiresistant respiratory tract and wound infections.
(2020-12-10)
La resistencia a los antibióticos (AMR) es un problema grave que debe abordarse lo antes posible. La colistina y la amikacina representan unos de los pocos antibióticos eficaces contra las infecciones de las bacterias ...
Evaluación clínica y análisis coste-efectividad del envío de mensajes motivacionales como herramienta adyuvante para dejar de fumar.
(2020-11-27)
El tabaquismo constituye la primera causa de morbi-mortalidad evitable a nivel mundial. Es uno de los mayores problemas de salud pública al que se ha tenido que enfrentar lahumanidad, matando hasta la mitad de sus consumidores. ...
Treatment of corneal inflammation by topical gene therapy with non-viral vectors as delivery systems of the interleukin-10 gene
(2020-07-21)
El proceso inflamatorio de la superficie ocular subyace en la base de importantes enfermedades que pueden provocar incluso la pérdida de la visión en los casos más graves. Actualmente, la terapia de elección de la inflamación ...
Nucleic Acid Delivery by Solid Lipid Nanoparticles Containing Switchable Lipids: Plasmid DNA vs. Messenger RNA
(MDPI, 2020-12-18)
The development of safe and effective nucleic acid delivery systems remains a challenge, with solid lipid nanoparticle (SLN)-based vectors as one of the most studied systems. In this work, different SLNs were developed, ...