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Cannabis use and nonuse in patients with first-episode psychosis: A systematic review and meta-analysis of studies comparing neurocognitive functioning
(Association of European Psychiatrists, 2020-01-31)
BACKGROUND.: The implications of cannabis use in the onset of early psychosis and the severity of psychotic symptoms have resulted in a proliferation of studies on this issue. However, few have examined the effects of ...
Cortical thinning over two years after first-episode psychosis depends on age of onset.
(Nature Portfolio, 2022-03-11)
[EN] First-episode psychosis (FEP) patients show structural brain abnormalities at the first episode. Whether the cortical changes that follow a FEP are progressive and whether age at onset modulates these changes remains ...
Cognitive Enhancers in Schizophrenia: a Systematic Review and Meta-Analysis of Alpha-7 Nicotinic Acetylcholine Receptor Agonists for Cognitive Deficits and Negative Symptoms
(Frontiers Media, 2021-04-06)
Background: Schizophrenia is a severe and enduring disease and is one of the leading causes of disability worldwide. Cognitive impairment is a core clinical symptom that plays a crucial role in functional outcomes and ...
Atxikimendua eta Aurpegi-Emozioen Antzematea Mugako Nortasunaren Nahasmendua duten Pazienteetan
(2021-04-30)
Mugako Nortasunaren Nahasmendua (MNN) atxikimenduaren zailtasunekin lotu izan da, helduaroan bereziki atxikimendu-antsietate maila altuarekin. Bestalde, MNN-n Aurpegi-Emozioen Antzematea (AEA) aztertu dituzten ikerketetan ...
Impact of previous tobacco use with or without cannabis on first psychotic experiences in patients with first-episode psychosis
(Elsevier, 2021-08-05)
OBJECTIVE: There is high prevalence of cigarette smoking in individuals with first-episode psychosis (FEP) prior to psychosis onset. The purpose of the study was to determine the impact of previous tobacco use with or ...
Gender-Based Analysis of the Psychological Impact of the COVID-19 Pandemic on Healthcare Workers in Spain
(Frontiers Media, 2021-07-20)
Purpose: This study aims to analyze from a gender perspective the psychological distress experienced by the medical workforce during the peak of the pandemic in Spain. Methods: This is a single-center, observational analytic ...
Microglia: Development of a human in vitro model, analysis of motility and effects of phagocytosis in the hippocampal neurogenic niche
(2022-10-26)
This PhD Thesis discusses several topics related to microglia, the resident macrophages of the brain parenchyma. They are derived from yolk sack primitive macrophages that colonize the brain early during embryonic development. ...
Risk factors associated with COVID-19 infection and mortality in nursing homes
(Elsevier, 2022-10)
Objective: The aim of this paper was to analyse the association of demographic, clinical and pharmacological risk factors with the presence of SARS-COV-2 virus infection, as well as to know the variables related to mortality ...
Impulse-control disorders in Parkinson's Disease: development of an animal model
(2020-11-12)
El objetivo de la presente tesis es el desarrollo de un modelo animal de parkinsonismo e impulsividad inducido por la administración del agonista dopaminérgico pramipexol (PPX).La enfermedad de Párkinson (EP) es una ...
Heart-brain synchronization breakdown in Parkinson's disease
(Nature, 2022-05)
Heart rate variability (HRV) abnormalities are potential early biomarkers in Parkinson's disease (PD) but their relationship with central autonomic network (CAN) activity is not fully understood. We analyzed the synchronization ...