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La separación y el conflicto parental: efectos en las relaciones afectivas de los hijos adultos jóvenes.
(2015-09-16)
Esta tesis doctoral parte de un doble objetivo: 1) Analizar la capacidad predictiva de la separación parental y del conflicto interparental sobre la ansiedad y evitación del apego, las expectativas hacia las relaciones de ...
Análisis de la influencia del contexto familiar en el desarrollo cognitivo de niñas y niños de 4 años.
(2015-09-25)
Este trabajo se enmarca dentro de un estudio de diseño prospectivo de base poblacional, multicentrico y longitudinal (N=346) en el marco del Proyecto INMA (www. infanciaymedioambiente.org). Profundiza y genera conocimiento ...
A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis
(Oxford University Pres, 2015-10-01)
Several variants in strong linkage disequilibrium (LD) at the SP140 locus have been associated with multiple sclerosis (MS), Crohn's disease (CD) and chronic lymphocytic leukemia (CLL). To determine the causal polymorphism, ...
Central immune alterations in passive strategy following chronic defeat stress
(Elsevier, 2015-11-10)
The relationship between stress, mood disorders and immune disorders is known, but what remains to be resolved is why certain individuals are more susceptible than others to suffer different disorders, along with the ...
Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61) levels
(Wiley, 2015-08-28)
Brain-derived neurotrophic factor (BDNF) regulates synaptic strengthening and memory consolidation, and altered BDNF expression is implicated in a number of neuropsychiatric and neurodegenerative disorders. BDNF potentiates ...