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Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients
(Elsevier, 2018-08)
Background: Sepsis is a life-threatening illness with a challenging diagnosis. Current serum biomarkers are not sensitive enough for diagnosis. With the aim of finding proteins associated with sepsis, serum protein profile ...
Birsortze neuralean erabiltzeko hortz muineko ama zelulen gaitasun funtzionalaren azterketa
(2018-12-19)
Ezaguna da hortz muin helduak zelula ama populazio garrantzitsu bat duela barnean, hauei, hortz muineko zelula amak deritze (ingelesez, dental pulp stem cells, DPSCs). Oinarrizko egoeran aurkezten dituzten zelula neuralen ...
Dexamethasone Protects Retinal Ganglion Cells But Not Muller Glia Against Hyperglycemia In Vitro
(Public Library Science, 2018-11-26)
Diabetic retinopathy (DR) is a common complication of diabetes, for which hyperglycemia is a major etiological factor. It is known that retinal glia (Muller cells) and retinal ganglion cells (RGCs) are affected by diabetes, ...
Development of new methods in biomedical engineering for brain connectivity biomarkers in epilepsy and other pathological conditions
(2018-05-07)
The aim of this thesis is to humbly explore the application of diverse methodologies and theories comingfrom Computer Sciences, Mathematics and Physics in the field of neurosciences, with an special focus onneurodegenerative ...
An E2F7-Dependent Transcriptional Program Modulates DNA Damage Repair And Genomic Stability
(Oxford University Press, 2018-05-18)
The cellular response to DNA damage is essential for maintaining the integrity of the genome. Recent evidence has identified E2F7 as a key player in DNA damage-dependent transcriptional regulation of cell-cycle genes. ...
Baseline tissue levels of trace metals and metalloids to approach ecological threshold concentrations in aquatic macroinvertebrates
(Elsevier, 2018-04-24)
Within the framework of the European Environmental Quality Standards Directive, the biota was recognized as a suitable matrix for monitoring water quality. In the Nalón River basin (North Spain), a catchment subject to ...
Derivation of sediment Hg quality standards based on ecological assessment in river basins
(Elsevier, 2018-11-28)
The Environmental Quality Standards (EQS) directive was an important improvement of long-term water quality monitoring at the European level, leading to the use of sediments and biota as relevant matrices for assessing ...