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Isolation and characterization of myogenic precursor cells from human cremaster muscle
(Nature Publishing, 2019-03-05)
Human myogenic precursor cells have been isolated and expanded from a number of skeletal muscles, but alternative donor biopsy sites must be sought after in diseases where muscle damage is widespread. Biopsy sites must be ...
Caracterización celular y molecular de la miogénesis dérmica de ratón y su posible traslación al humano
(2018-03-12)
El estudio de la miogénesis y de diversas enfermedades neuromusculares requiere generalmente el uso de técnicas in vitro, idealmente de cultivos primarios tridimensionales.En esta tesis, se ha identificado la población de ...
De la neurastenia a la enfermedad postesfuerzo: evolución de los criterios diagnósticos del síndrome de fatiga crónica/encefalomielitis miálgica
(Elsevier, 2019-06-08)
[ES] Presentamos la evolución de la terminología y los criterios diagnósticos para el síndrome de fatiga crónica/encefalomielitis miálgica.
Este síndrome es una entidad compleja y controvertida, de etiología desconocida, ...
Cerebro, lipidómica y alzheimer: estudio de biomarcadores y neuroimagen en personas sanas.
(2020-07-16)
El objetivo general de esta tesis es ampliar el conocimiento sobre la fisiopatología de la EA e investigar la posible interrelación existente entre tres hechos biológicos cerebrales que podrían estar involucrados en los ...
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Neurological Entity?
(MDPI, 2021-09-27)
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disorder of unknown physiopathology with multisystemic repercussions, framed in ICD-11 under the heading of neurology (8E49). There is no specific test to ...
Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model
(Nature Research, 2021-09-15)
The development of new effective and safer therapies for osteoporosis, in addition to improved diagnostic and prevention strategies, represents a serious need in the scientific community. Micro-CT image-based analyses in ...
Glyceryl trinitrate in first-episode psychosis unmedicated with antipsychotics: A randomised controlled pilot study
(Sage, 2020-08)
There is a pressing need for new classes of treatment for psychosis. A key therapeutic target for novel compounds is the NMDA receptor, which may be modulated by nitric oxide donors such as sodium nitroprusside (SNP). ...
Universal and selective interventions to promote good mental health in young people: Systematic review and meta-analysis
(Elsevier, 2020-12)
Promotion of good mental health in young people is important. Our aim was to evaluate the consistency and magnitude of the efficacy of universal/selective interventions to promote good mental health. A systematic ...
Annual Research Review: Prevention of Psychosis in Adolescents - Systematic Review and Meta-Analysis of Advances in Detection, Prognosis and Intervention
(Wiley, 2021-05)
Background The clinical high-risk state for psychosis (CHR-P) paradigm has facilitated the implementation of psychosis prevention into clinical practice; however, advancements in adolescent CHR-P populations are less ...
Implementing Precision Psychiatry: a Systematic Review of Individualized Prediction Models for Clinical Practice
(Oxford University Press, 2021-03-16)
BACKGROUND: The impact of precision psychiatry for clinical practice has not been systematically appraised. This study aims to provide a comprehensive review of validated prediction models to estimate the individual risk ...