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Malaria Vaccine Adjuvants: Latest Update and Challenges in Preclinical and Clinical Research
(Hindawi Publishing Corporation, 2013)
There is no malaria vaccine currently available, and the most advanced candidate has recently reported a modest 30% efficacy against clinical malaria. Although many efforts have been dedicated to achieve this goal, the ...
Clay Minerals as Bioink Ingredients for 3D Printing and 3D Bioprinting: Application in Tissue Engineering and Regenerative Medicine
(MDPI, 2021-10-28)
The adaptation and progress of 3D printing technology toward 3D bioprinting (specifically adapted to biomedical purposes) has opened the door to a world of new opportunities and possibilities in tissue engineering and ...
Effectiveness of Mobile Applications to Quit Smoking: Systematic Review and Meta-Analysis
(E.U. European Publishing, 2021-04)
Introduction: Tobacco is the leading cause of preventable mortality. The use of mobile phones has grown exponentially, becoming a powerful tool to be used in health care.
Methods: In order to assess the effectiveness ...
Modulation of Conductivity of Alginate Hydrogels Containing Reduced Graphene Oxide through the Addition of Proteins
(MDPI, 2021-09-15)
Modifying hydrogels in order to enhance their conductivity is an exciting field with applications in cardio and neuro-regenerative medicine. Therefore, we have designed hybrid alginate hydrogels containing uncoated and ...
Mesenchymal stromal cells encapsulated in licensing hydrogels exert delocalized systemic protection against ulcerative colitis via subcutaneous xenotransplantation
(Elsevier, 2022-03)
[EN] The ability of mesenchymal stromal cells (MSCs) to release a plethora of immunomodulatory factors makes them valuable candidates to overcome inflammatory bowel diseases (IBD). However, this cell therapy approach is ...
Therapeutic Opportunities and Delivery Strategies for Brain Revascularization in Stroke, Neurodegeneration, and Aging
(American Society of Pharmacology Experimental Therapeutics, 2022-04)
[EN] Central nervous system (CNS) diseases, especially acute ischemic events and neurodegenerative disorders, constitute a public health problem with no effective treatments to allow a persistent solution. Failed therapies ...
3D Bioprinting of Functional Skin Substitutes: From Current Achievements to Future Goals
(MDPI, 2021-04-14)
The aim of this review is to present 3D bioprinting of skin substitutes as an efficient approach of managing skin injuries. From a clinical point of view, classic treatments only provide physical protection from the ...
Characterization of encapsulated porcine cardiosphere-derived cells embedded in 3D alginate matrices
(Elsevier, 2021-04-15)
Myocardial infarction is caused by an interruption of coronary blood flow, leading to one of the main death causes worldwide. Current therapeutic approaches are palliative and not able to solve the loss of cardiac tissue. ...
Bioinspired three-dimensional multifunctional systems to enhance the therapeutic potential of mesenchymal stromal cells
(2019-12-16)
Mesenchymal stromal cells (MSCs) present the ability to secrete important immunomodulatory factors, and therefore, hold great potential for the treatment of multiple inflammatory and immune disorders. However, for the ...
Force spectroscopy-based simultaneous topographical and mechanical characterization to study polymer-to-polymer interactions in coated alginate microspheres
(Nature Publishing, 2019-12-27)
Cell-laden hydrogel microspheres have shown encouraging outcomes in the fields of drug delivery, tissue engineering or regenerative medicine. Beyond the classical single coating with polycations, many other different coating ...