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Ocoxin as a complement to first line treatments in cancer
(Ivyspring International Publisher, 2021)
Chemotherapy and radiotherapy are the most frequent treatment for patients suffering from malignant progression of cancer. Even though new treatments are now being implemented, administration of these chemotherapeutic ...
Arming NK cells with chimeric antigen receptors (CARs) for treatment of refractory and/or relapsed hematological cancers: preclinical study to determine the best cell source.
(2020-02-10)
Acute Lymphoblastic Leukemia (ALL) and Chronic Lymphocytic Leukemia (CLL) are the most prevalent hematological cancers in children and elder patients respectively. Sometimes, standard treatments are not enough for curing ...
Estimulación termoalgésica controlada para explorar nuevos biomarcadores de la percepción del dolor.
(2023-12-12)
¿Es posible que las ondas eléctricas del cerebro (registradas mediante EEG) y su interacción con las hemodinámicas (registradas mediante PPG) puedan determinar de alguna manera situaciones de dolor progresivo? La sinergia ...
Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells
(BioMed Central, 2011-10-07)
Background -- N-(4-hydroxyphenyl)retinamide (4-HPR, fenretinide) is a synthetic retinoid with potent pro-apoptotic activity against several types of cancer, but little is known regarding mechanisms leading to chemoresistance. ...
Characterization of a mouse model of autism. Focus on the excitatory/inhibitory and dopaminergic pathways
(2023-10-27)
El Trastorno del Espectro Autista (TEA) es una condición del neurodesarrollo que presenta diversos síntomas, entre los que destacan los déficits en comunicación y comportamiento social y la presencia de movimientos ...
Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach
(MDPI, 2021-06-11)
Heat shock protein (Hsp) synthesis is upregulated in a wide range of cancers to provide the appropriate environment for tumor progression. The Hsp110 and Hsp70 families have been associated to cancer cell survival and ...
Nanostructured scaffolds based on bioresorbable polymers and graphene oxide induce the aligned migration and accelerate the neuronal differentiation of neural stem cells
(Elsevier, 2021-01-31)
Within the field of neural tissue engineering, there is a huge need for the development of materials that promote the adhesion, aligned migration and differentiation of stem cells into neuronal and supportive glial cells. ...
Analysis of different strategies for in vitro diagnosis of human humoral biomarkers based on solid support immobilization
(2023-11-03)
The study of biomarkers and their detection in human fluids represents one of the best ways to improve the diagnosis and prevention of diseases. The use of human fluids for biomarker analysis can facilitate a friendly and ...
Novel proteomic and lipidomic biomarkers for limbal epithelial stem cell identification and corneal transplant monitoring
(2022-07-28)
El objeto de esta tesis doctoral ha sido la caracterización proteómica y lipidómica de cinco poblaciones celulares de la córnea humana para la identificación de nuevos biomarcadores de cada tipo celular. Además, se han ...
Docosahexaenoic acid reduces cerebral damage and ameliorates long-term cognitive impairments caused by neonatal hypoxia-ischemia in rats
(Springer, 2011-10-29)
As the interest in the neuroprotective possibilities
of docosahexaenoic acid (DHA) for brain injury has grown in the recent years, we aimed to investigate the long-term effects of this fatty acid in an experimental model ...