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Mesenchymal stromal cells encapsulated in licensing hydrogels exert delocalized systemic protection against ulcerative colitis via subcutaneous xenotransplantation
(Elsevier, 2022-03)
[EN] The ability of mesenchymal stromal cells (MSCs) to release a plethora of immunomodulatory factors makes them valuable candidates to overcome inflammatory bowel diseases (IBD). However, this cell therapy approach is ...
Therapeutic Opportunities and Delivery Strategies for Brain Revascularization in Stroke, Neurodegeneration, and Aging
(American Society of Pharmacology Experimental Therapeutics, 2022-04)
[EN] Central nervous system (CNS) diseases, especially acute ischemic events and neurodegenerative disorders, constitute a public health problem with no effective treatments to allow a persistent solution. Failed therapies ...
Bioactive and degradable hydrogel based on human platelet-rich plasma fibrin matrix combined with oxidized alginate in a diabetic mice wound healing model
(Elsevier, 2022-04)
[EN] In the present study we developed an injectable, bioactive and degradable hydrogel composed of alginate at 2.5% oxidation degree and calcium-activated platelet rich plasma (PRP) for wound healing applications ...
Decellularized Extracellular Matrix-Based Bioinks for Tendon Regeneration in Three-Dimensional Bioprinting
(MDPI, 2022-10-26)
In the last few years, attempts to improve the regeneration of damaged tendons have been rising due to the growing demand. However, current treatments to restore the original performance of the tissue focus on the usage ...
Design and evaluation of novel electroconductive alginate hydrogels based on graphene oxide and reduced graphene oxide with applications in tissue engineering
(2022-10-19)
El alginato es uno de los mejores biomateriales para la preparación de estos hidrogeles debido a sus excelentes propiedades, entre ellas su alta biocompatibilidad y facilidad de gelificación. Los hidrogeles de alginato han ...
Key Factors in Effective Patient-Tailored Dosing of Fluoroquinolones in Urological Infections: Interindividual Pharmacokinetic and Pharmacodynamic Variability
(MDPI, 2022-05-11)
Fluoroquinolones (FQs) are a critical group of antimicrobials prescribed in urological infections as they have a broad antimicrobial spectrum of activity and a favorable tissue penetration at the site of infection. However, ...
Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review
(Elsevier, 2022-01)
[EN] Bipolar disorder (BD) might be associated with higher infection rates of coronavirus disease (COVID-19) which in turn could result in worsening the clinical course and outcome. This may be due to a high prevalence of ...
Enfoque múltiple sobre la calidad sensorial del queso DOP Idiazabal
(2022-07-18)
Esta tesis consta de tres estudios independientes, aunque con un hilo en común: la calidad sensorial del queso DOP Idiazabal.En el primer estudio se abordó la adaptación de la metodología utilizada por el panel de ...
Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects
(Elsevier, 2022-02)
P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX) resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2, HIF-1alpha, miRNAs, and long noncoding ...
The 3D Bioprinted Scaffolds for Wound Healing
(MDPI, 2022-02-21)
Skin tissue engineering and regeneration aim at repairing defective skin injuries and progress in wound healing. Until now, even though several developments are made in this field, it is still challenging to face the ...