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Neuroprotective Effect of Melatonin: A Novel Therapy against Perinatal Hypoxia-Ischemia
(MDPI AG, 2013-04-29)
One of the most common causes of mortality and morbidity in children is perinatal hypoxia-ischemia (HI). In spite of the advances in neonatology, its incidence is not diminishing, generating a pediatric population that ...
Computational predictive modeling of integrated cerebral metabolism, electrophysiology and hemodynamics.
(2019-02-12)
Understanding the energetic requirement of brain cells during resting state and during high neural activity is a very active research area where mathematical models have contributed significantly by providing a context for ...
Notch/Wnt Cross-Signalling Regulates Stemness Of Dental Pulp Stem Cells Through Expression Of Neural Crest And Core Pluripotency Factors
(AO Research Institute Davos-Ari, 2017-07)
Dental pulp stem cells (DPSCs) from adult teeth express neural crest (NC) markers together with core transcriptional factors associated with stem cell pluripotency, such as Oct4a, Sox2, c-Myc, Rex1, Stella/Dppa3, Ssea1/Fut4, ...
Human DenPulp Stem Cells Grown in Neurogenic Media Differentiate Into Endothelial Cells and Promote Neovasculogenesis in the Mouse Brain
(Frontiers Media, 2019-03-28)
Dental pulp stem cells (DPSCs) have the capacity to give rise to cells with neuronal-like phenotypes, suggesting their use in brain cell therapies. In the present work, we wanted to address the phenotypic fate of adult ...
Birsortze neuralean erabiltzeko hortz muineko ama zelulen gaitasun funtzionalaren azterketa
(2018-12-19)
Ezaguna da hortz muin helduak zelula ama populazio garrantzitsu bat duela barnean, hauei, hortz muineko zelula amak deritze (ingelesez, dental pulp stem cells, DPSCs). Oinarrizko egoeran aurkezten dituzten zelula neuralen ...
Wnt signaling reprograms metabolism in dental pulp stem cells
(Wiley, 2019-08)
Human dental pulp stem cells (DPSCs) can differentiate to a wide range of different cell lineages, and share some gene expression and functional similarities with pluripotent stem cells. The stemness of DPSCs can also be ...
Identification of a biomarker panel for colorectal cancer diagnosis
(BioMed Central, 2012-01-26)
Background: Malignancies arising in the large bowel cause the second largest number of deaths from cancer in the Western World. Despite progresses made during the last decades, colorectal cancer remains one of the most ...
Cell Reprogramming, IPS Limitations, and Overcoming Strategies in Dental Bioengineering
(SAGE-Hindawi Access to Research, 2012-03-29)
The procurement of induced pluripotent stem cells, or IPS cells, from adult differentiated animal cells has the potential to revolutionize future medicine, where reprogrammed IPS cells may be used to repair disease-affected ...
Role of notch and wnt signaling in metabolic and epigenetic reprogramming of human dental pulp stem cells (DPSCs)
(2019-03-01)
Las Células Stem de Pulpa Dental (DPSCs; en inglés) son células madre extraídas de la pulpa dental de terceros molares de pacientes. Presentan unas propiedades que las convierte en un recurso especialmente interesante para ...
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2
(BioMed Central, 2011-08)
Background: Human melanoma frequently colonizes bone marrow (BM) since its earliest stage of systemic dissemination, prior to clinical metastasis occurrence. However, how melanoma cell adhesion and proliferation mechanisms ...