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Lipid Nanoparticles as Carriers for RNAi against Viral Infections: Current Status and Future Perspectives
(Hindawi Publishing, 2014)
The efforts made to develop RNAi-based therapies have led to productive research in the field of infections in humans, such as hepatitis C virus (HCV), hepatitis B virus (HBV), human immunodeficiency virus (HIV), human ...
An update of the J48Consolidated WEKA’s class: CTC algorithm enhanced with the notion of coverage
(2016-02-12)
This document aims to describe an update of the implementation of the J48Consolidated class within WEKA platform. The J48Consolidated class implements the CTC algorithm [2][3] which builds a unique decision tree based on ...
Low Molecular Weight Chitosan (LMWC)-based Polyplexes for pDNA Delivery: From Bench to Bedside
(MDPI, 2014-06)
Non-viral gene delivery vectors are emerging as a safer alternative to viral vectors. Among natural polymers, chitosan (Ch) is the most studied one, and low molecular weight Ch, specifically, presents a wide range of ...
Development of nucleic acid vaccines: use of self-amplifying RNA in lipid nanoparticles
(Dove Medical Press, 2014)
Self-amplifying RNA or RNA replicon is a form of nucleic acid-based vaccine derived from either positive-strand or negative-strand RNA viruses. The gene sequences encoding structural proteins in these RNA viruses are ...
Analytical method development for the uptake study of different organic pollutants by crops cultivated in compost-amended soils
(2015-12-11)
Two unavoidable residues from wastewater treatment plants (WWTPs) are effluent water and sewage sludge. The latter, isconsidered one of the largest pollutant sink because it contains a broad range of microorganisms and ...
Behaviour modelling with data obtained from the Internet and contributions to cluster validation
(2016-02-05)
[EN]This PhD thesis makes contributions in modelling behaviours found in different types of data acquired from the Internet and in the field of clustering evaluation. Two different types of Internet data were processed, ...
Essays on the effect of renewable energy production in the spanish electricity market.
(2016-02-26)
El camino hacia una economía baja en carbono es una de las prioridades políticas actuales de la Unión Europea. En España, la Energía Renovable (ER) emergió a partir de la introducción del sistema de Feed-in Tariffs. La ...
Generation of the database gurekddcup
(2017-02-10)
The database gureKDDCup has been generated within the UADI project (Unsupervised Anomaly Detection for Intrusion detection system) in which a classifier that detects intrusions or attacks in network based systems was ...
Dipeptidyl-Peptidase IV Activity Is Correlated with Colorectal Cancer Prognosis
(Public Library Science, 2015-03-19)
Background
Dipeptidyl-peptidase IV (EC 3.4.14.5) (DPPIV) is a serine peptidase involved in cell differentiation, adhesion, immune modulation and apoptosis, functions that control neoplastic transformation. Previous ...