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Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum
(MDPI, 2018-09)
We have previously shown that Classical Swine Fever Virus (CSFV) p7 is an essential nonstructural protein with a viroporin activity, a critical function in the progression of virus infection. We also identified p7 domains ...
Characterization of the HIV-1 membrane and its interactions with anti-viral compounds using advanced microscopy techniques
(2017-12-19)
El virus de la inmunodeficiencia humana (VIH) es un retrovirus perteneciente al género Lentivirus que infecta principalmente linfocitos T CD4+. El síndrome de inmunodeficiencia adquirida (SIDA) es un espectro de enfermedades ...
Analysis, overview and creation of an Arabic LVCSR
(2018-10-10)
As the standardized version of the Arabic Language, Modern Standard Arabic (MSA) is the most prevalent form of this language. MSA is also the third most spoken language in the world with over 300 million speakers. Moreover, ...
Herramienta de diagnóstico y evaluación para voces alaríngeas
(2016-12-21)
Tras una laringectomía total, la calidad de la voz del paciente se degrada considerablemente, obteniendo como resultado lo que se denomina ¨voz alaríngea¨. Los pacientes de este tipo de cirugías necesitan asistir a un ...
Mechanisms of MPER helix binding at membrane interfaces and implications for the broad neutralization of HIV by antibodies
(2016-12-16)
En esta tesis se lleva a cabo un estudio detallado de la función que desempeña el lazo CDR-H3 de losanticuerpos anti MPER 4E10 y 10E8 en al unión y neutralización del VIH así como la contribución de launión directa a lípidos ...
Changes in lipids and formation of derived compounds during fish cooking and in vitro gastrointestinal digestion of edible oils, model systems and processed fish meat
(2017-03-07)
En la presente tesis doctoral se plantearon cuatro objetivos principales. En el primer objetivo, se estudiaron los cambios provocados por el proceso de cocinado en los lípidos y/o perfil volátil del pescado mediante ...
Explicit-in-time variational formulations for goal-oriented adaptivity.
(2019-10-01)
Goal-Oriented Adaptivity (GOA) is a powerful tool to accurately approximate physically relevantfeatures of the solution of Partial Differential Equations (PDEs). It delivers optimal grids to solvechallenging engineering ...
Enantioselective synthesis of a-aminophosphonic acid derivatives.
(2019-11-25)
Los ácidos -aminofosfónicos y sus derivados son estructuras muy frecuentes en productos con alto interés biológico como fármacos y agroquímicos.Durante las últimas décadas, el elevado interes de la industria en derivados ...
Diastolic Dysfunction and Exercise Capacity in Patients with Metabolic Syndrome and Overweight/Obesity
(Elsevier, 2019-03)
Background: Left ventricle diastolic dysfunction (LVDD) is a common finding in high risk individuals, its presence being associated with reduced exercise capacity (EC). We assessed the prevalence of LVDD, applying the 2016 ...
Brønsted Base Catalyzed One-Pot Synthesis od Stereodefined Six-Member Carbocycles Featuring Transient Trienolates and a Key Intramolecular 1,6-Addition
(Wiley-VCH, 2019-07-31)
Acatalyst-driven one-pot reaction sequence is
developed for the enantio- and diastereoselective synthesis of
tetrasubstituted cyclohexenes from simple unsaturated ketones
or thioesters.The method involves atertiary ...