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Accumulated Bending Energy Elicits Neutral Sphingomyelinase Activity in Human Red Blood Cells
(Elservier, 2012-05-02)
[EN] We propose that accumulated membrane bending energy elicits a neutral sphingomyelinase (SMase) activity in human erythrocytes. Membrane bending was achieved by osmotic or chemical processes, and SMase activity was ...
The IHG index for hydromorphological quality assessment of rivers and streams: updated version
(AIL, 2011)
[EN]An updated version of the IHG index is presented. The index is based on three appraisal parameters: 1) the functional quality of the fluvial system, including a) flow regime naturalness, b) sediment supply and mobility, ...
Size-effect and scaling power-law for superelasticity in Shape Memory Alloys at the nano-scale
(Macmillan Publishers Limited, part of Springer Nature., 2017-05-29)
Shape-memory alloys capable of a superelastic stress-induced phase transformation and a high displacement actuation have promise for applications in micro-electromechanical systems for wearable healthcare and flexible ...
The effect of hydroxylated fatty acid-containing phospholipids in the remodeling of lipid membranes
(Elsevier B.V., 2014-01-24)
The synthetic fatty acid 2-hydroxyoleic acid (2OHOA) is an antitumor drug that regulates membrane lipid composition and structure. An important effect of this drug is the restoration of sphingomyelin (SM) levels in cancer ...
Conformational stabilization as a strategy to prevent nucleophosmin mislocalization in leukemia
(Nature Research, 2017-10-24)
Nucleophosmin (NPM) is a nucleolar protein involved in ribosome assembly and cell homeostasis. Mutations in the C-terminal domain of NPM that impair native folding and localization are associated with acute myeloid leukemia ...
Shortcuts to adiabaticity in optical waveguides using fast quasiadiabatic dynamics
(Optica Publishing Group, 2017-01-03)
We propose a fast quasiadiabatic approach to the design of optical waveguide devices. This approach distributes the system adiabaticity homogeneously over the device length, thus providing a shortcut to adiabaticity at a ...
Human ATG3 binding to lipid bilayers: role of lipid geometry, and electric charge
(Nature Publishing, 2017-11-15)
Specific protein-lipid interactions lead to a gradual recruitment of AuTophaGy-related (ATG) proteins to the nascent membrane during autophagosome (AP) formation. ATG3, a key protein in the movement of LC3 towards the ...
Triacylglycerol mimetics regulate membrane interactions of glycogen branching enzyme: implications for therapy
(Elsevier, 2017-06-19)
Adult polyglucosan body disease (APBD) is a neurological disorder characterized by adult-onset neurogenic bladder, spasticity, weakness, and sensory loss. The disease is caused by aberrant glycogen branching enzyme (GBE) ...
Small Form-Factor Driver for Power LEDs Powered with One Element Battery
(Springer, 2011)
The present paper is focused on designing small form-factor drivers for high-power LEDs, which are fed with one battery element. Standard power supply architectures are not suitable due to the design requirements and ...
Multiple-Criteria Decision-Making Tool for Local Governments to Evaluate the Global and Local Sustainability of Transportation Systems in Urban Areas: Case Study
(ASCE, 2017-10-24)
Efficient management of urban transportation systems is a challenge for any local government that wishes to improve public wellbeing and comfort. With that end in mind, this paper proposes a tool for decision making and ...