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Astrocyte dystrophy in ageing brain parallels impaired synaptic plasticity
(2021-03)
Little is known about age-dependent changes in structure and function of astrocytes and of the impact of these on the cognitive decline in the senescent brain. The prevalent view on the age-dependent increase in reactive ...
Secondary Impacts of COVID-19 Pandemic in Fatigue, Self-Compassion, Physical and Mental Health of People with Multiple Sclerosis and Caregivers: The Teruel Study
(MDPI, 2021-09-18)
The secondary impacts of the COVID-19 pandemic are distress triggers and risk factors for mental health. Conversely, self-compassion skills and compassionate thoughts/behaviors towards suffering may contribute to their ...
Lifestyle-dependent microglial plasticity: training the brain guardians
(BMC, 2021-08-03)
Lifestyle is one of the most powerful instruments shaping mankind; the lifestyle includes many aspects of interactions with the environment, from nourishment and education to physical activity and quality of sleep. All ...
Characterization of blood markers and their implication in human aging.
(2020-01-13)
Aging is a universal, complex and heterogeneous process. In the last decades, an overall improvement in the quality of life and consequent increase in life expectancy has been achieved. In contrast, the disability-free ...
Alterations of the Hippocampal Neurogenic Niche in a Mouse Model of Dravet Syndrome
(Frontiers Media, 2020-07-21)
Hippocampal neurogenesis, the process by which neural stem cells (NSCs) continuously generate new neurons in the dentate gyrus (DG) of most mammals including humans, is chiefly regulated by neuronal activity. Thus, severe ...
BASP1 labels neural stem cells in the neurogenic niches of mammalian brain
(Springer Nature, 2021-03-10)
The mechanisms responsible for determining neural stem cell fate are numerous and complex. To begin to identify the specific components involved in these processes, we generated several mouse neural stem cell (NSC) antibodies ...
Quantifying Knowledge of Alzheimer's Disease: an Analysis of the Psychometric Properties of the Alzheimer's Disease Knowledge Scale
(Springer, 2021-06)
Introduction: The Alzheimer's Disease Knowledge Scale (ADKS) is one of the most popular instruments for assessing a person's knowledge regarding Alzheimer's disease (AD). The objective of this study was to explore ADKS ...
Ultrastructural and physiological studies on the cannabinoid CB1 receptor localized in astroglia.
(2021-10-28)
The cannabinoid CB1 receptor-mediated functions in astrocytes are highly dependent on the CB1 receptor
distribution in these glial cells relative to neuronal sites, particularly at the nearby synapses under normal
or ...
Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
(Elsevier, 2021-01-01)
BACKGROUND: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to ...
Cognition in Recent Suicide Attempts: Altered Executive Function
(Frontiers Media, 2021-07-22)
Background: Neuropsychological alterations can lead to inaccurate perception, interpretation, and response to environmental information, which could be a risk factor for suicide.
Methods: Ninety-six subjects were recruited ...