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Physiological modules for generating discrete and rhythmic movements: Component analysis of EMG signals
(Frontiers Research Foundation, 2015-01-09)
A central question in Neuroscience is that of how the nervous system generates the spatiotemporal commands needed to realize complex gestures, such as handwriting. A key postulate is that the central nervous system (CNS) ...
Aplicación clínica de las vesículas extracelulares en la esclerosis múltiple
(2015-12-18)
En esta tesis se ha investigado la biología de las vesículas extracelulares en relación a la esclerosis múltiple,
una enfermedad del sistema nervioso central, desmielinizante y con un claro componente
autoinmune como ...
Dantza eta ibiltzearen arteko desberdintasun sentsoriomotore eta neuropsikologikoak adineko emakumeetan
(2020-07-17)
El deterioro de la salud relacionado con el envejecimiento afecta más y en mayor medida a las mujeres. Las diferencias en la función sensoriomotriz y neuropsicológica en las personas mayores podrían estar relacionadas con ...
Allostatic hypermetabolic response in PGC1 alpha/beta heterozygote mouse despite mitochondrial defects
(Wiley, 2021-09)
Aging, obesity, and insulin resistance are associated with low levels of PGC1 alpha and PGC1 beta coactivators and defective mitochondrial function. We studied mice deficient for PGC1 alpha and PGC1 beta [double heterozygous ...
Genetics of Somatotype and Physical Fitness in Children and Adolescents
(Wiley, 2021-05)
Objectives To analyze the influence of genetic and environmental factors on the variation in somatotype, physical fitness, and their mutual associations. Methods Twins from 214 pairs (87 monozygotic) of the Autonomous ...
Hepatokines and adipokines in NASH-related hepatocellular carcinoma
(Elsevier, 2020-11-05)
Summary
The incidence of hepatocellular carcinoma (HCC) is increasing in industrialised societies; this is likely
secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD), its progressive form ...
Systematic analysis of chemical-protein interactions from zebrafish embryo by proteome-wide thermal shift assay, bridging the gap between molecular interactions and toxicity pathways
(Elsevier, 2021-10-30)
[EN]The molecular interaction between chemicals and proteins often promotes alteration of cellular function. One of the challenges of the toxicology is to predict the impact of exposure to chemicals. Assessing the impact ...
Anti-TNFα treatment in Crohn’s disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status
(Wiley, 2021-11)
Background and Aims An association between Crohn's disease (CD) and hepatic steatosis has been reported. However, the underlying mechanisms of steatosis progression in CD are not clear. Among the most effective CD treatments ...