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Lysophosphatidic acid receptor 1 labels seizure-induced hippocampal reactive neural stem cells and controls their activation.
(2018-11-27)
En la regulación de la neurogénesis hipocampal adulta, un paso fundamental es la división de las células madre neurales (NSCs) ya que, tras activarse, se dividen varias veces consecutivas y se diferencian después en ...
Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds
(MDPI, 2018-12-08)
Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use ...
The Crossroad of Ion Channels and Calmodulin in Disease
(MDPI, 2019-01-02)
Calmodulin (CaM) is the principal Ca2+ sensor in eukaryotic cells, orchestrating the activity of hundreds of proteins. Disease causing mutations at any of the three genes that encode identical CaM proteins lead to major ...
Genome sequence and characterization of the bcs clusters for the production of nanocellulose from the low pH resistant strain Komagataeibacter medellinensis ID13488
(Wiley, 2019-02-22)
Komagataeibacter medellinensis ID13488 (formerly Gluconacetobacter medellinensis ID13488) is able to produce crystalline bacterial cellulose (BC) under high acidic growth conditions. These abilities make this strain desirable ...
Hole Making by Electrical Discharge Machining (EDM) of -TiAl Intermetallic Alloys
(MDPI, 2018-07)
Due to their excellent strength-to-weight ratio and corrosion and wear resistance, gamma-TiAl alloys are selected for aerospace and automotive applications. Since these materials are difficult to cut and machine by ...
Improving Stability Prediction in Peripheral Milling of Al7075T6
(MDPI, 2018-08)
Chatter is an old enemy to machinists but, even today, is far from being defeated. Current requirements around aerospace components call for stronger and thinner workpieces which are more prone to vibrations. This study ...
Understanding the role of E2F7 in the regulation of cellular proliferation and DNA damage responses.
(2018-10-23)
E2F transcription factors control diverse biological processes through regulation of target gene expression. The identification of a large set of genes regulated by each individual E2F, including those coding for microRNAs, ...
Golgi Oncoprotein GOLPH3 Gene Expression is Regulated by Functional E2F and CREB/ATF Promoter Elements
(MDPI, 2019-03-25)
The Golgi organelle duplicates its protein and lipid content to segregate evenly between two daughter cells after mitosis. However, how Golgi biogenesis is regulated during interphase remains largely unknown. Here we show ...
Sensitivity Analysis of Tool Wear in Drilling of Titanium Aluminides
(MDPI, 2019-03-06)
In the aerospace industry, a large number of holes need to be drilled to mechanically connect the components of aircraft engines. The working conditions for such components demand a good response of their mechanical ...
Reactive Disruption of the Hippocampal Neurogenic Niche After Induction of Seizures by Injection of Kainic Acid in the Amygdala
(Frontiers Media, 2019-08-20)
Adult neurogenesis persists in the adult hippocampus due to the presence of multipotent neural stem cells (NSCs). Hippocampal neurogenesis is involved in a range of cognitive functions and is tightly regulated by neuronal ...