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Targeting CAMKK2 and SOC Channels as a Novel Therapeutic Approach for Sensitizing Acute Promyelocytic Leukemia Cells to All-Trans Retinoic Acid
(MDPI, 2021-11-30)
Calcium ions (Ca2+) play important and diverse roles in the regulation of autophagy, cell death and differentiation. Here, we investigated the impact of Ca2+ in regulating acute promyelocytic leukemia (APL) cell fate in ...
Role of Dairy Foods, Fish, White Meat, and Eggs in the Prevention of Colorectal Cancer: A Systematic Review of Observational Studies in 2018–2022
(MDPI, 2022-08-21)
[EN] There is limited evidence to support the relationship between the consumption of animal-source foods other than red meat and processed meat and colorectal cancer (CRC) risk. We aimed to examine the recent available ...
Comparative Effects of Pterostilbene and Its Parent Compound Resveratrol on Oxidative Stress and Inflammation in Steatohepatitis Induced by High-Fat High-Fructose Feeding
(MDPI, 2020-10-24)
Different studies have revealed that oxidative stress and inflammation are crucial in NAFLD (Non-alcoholic fatty liver disease). The aim of this study is to analyze whether pterostilbene and resveratrol are able to either ...
Variability in the Beneficial Effects of Phenolic Compounds: A Review
(MDPI, 2022-05-04)
When analysing the beneficial effects of phenolic compounds, several factors that exert a clear influence should be taken into account. The content of phenolic compounds in foods is highly variable, directly affecting ...
Usefulness of Probiotics in the Management of NAFLD: Evidence and Involved Mechanisms of Action from Preclinical and Human Models
(MDPI, 2022-03-15)
The present review aims at analyzing the current evidence regarding probiotic administration for non-alcoholic fatty liver disease (NAFLD) management. Additionally, the involved mechanisms of action modulated by probiotic ...
The influence of dietary conditions in the effects of resveratrol on hepatic steatosis
(Royal Society of Chemistry, 2020-11-01)
Non-alcoholic fatty liver disease (NAFLD) is considered the major cause for the development of chronic liver alterations. Hepatic steatosis is the most benign and common form of NAFLD, although its potential to evolve into ...
Scientific Evidence Supporting the Beneficial Effects of Isoflavones on Human Health
(MDPI, 2020-12-17)
Isoflavones are phenolic compounds with a chemical structure similar to that of estradiol. They are present in several vegetables, mainly in legumes such as soy, white and red clover, alfalfa and beans. The most significant ...
Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
(MDPI, 2021-06-07)
An increase in the prevalence of noncommunicable chronic diseases has been occurring in recent decades. Among the deaths resulting from these conditions, cardiovascular diseases (CVD) stand out as the main contributors. ...
Gluten and FODMAPs Relationship with Mental Disorders: Systematic Review
(MDPI, 2021-05-31)
Nowadays, gluten and FODMAP food components (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) are increasingly studied due to their possible relation with extraintestinal-associated conditions. In ...
Gene–Diet Interactions in Colorectal Cancer: Survey Design, Instruments, Participants and Descriptive Data of a Case–Control Study in the Basque Country
(MDPI, 2020)
Epidemiologic studies have revealed inconsistent evidence of gene-diet interaction in
relation to colorectal cancer (CRC). The aim of this study was to analyze them in a sample of cases and
controls from the population-based ...