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Delivery of microRNAs as a remyelination strategy in multiple sclerosis.
(2019-01-18)
La esclerosis múltiple es una enfermedad del sistema nervioso central para la cual no existen fármacos que promuevan la remielinización. Por ello, la comunidad científica está realizando un gran esfuerzo por desarrollar ...
Análisis exploratorio de la influencia sobre dimensiones de personalidad de polimorfismos genéticos funcionales de la catecol-o-metiltransferasa, el transportador de serotonina y la monoamino oxidasa-A, y su interacción con variables ambientales adversas. Un estudio en pacientes con trastornos de la personalidad y controles sanos
(2019-01-22)
Se estudia el efecto de polimorfismos genéticos funcionales de la catecol-o-metil transferasa (COMT), del trasportador de serotonina y de la monoamino oxidasa-A (MAO-A) sobre dimensiones de la personalidad, según el modelo ...
Evidence of conditioned behavior in amoebae
(Nature, 2019-08-15)
Associative memory is the main type of learning by which complex organisms endowed with evolved nervous systems respond efficiently to certain environmental stimuli. It has been found in different multicellular species, ...
Interactome of the Autoimmune Risk Protein ANKRD55
(Frontiers Media, 2019-09-18)
The ankyrin repeat domain-55 (ANKRD55) gene contains intronic single nucleotide polymorphisms (SNPs) associated with risk to contract multiple sclerosis, rheumatoid arthritis or other autoimmune disorders. Risk alleles of ...
Reactive Disruption of the Hippocampal Neurogenic Niche After Induction of Seizures by Injection of Kainic Acid in the Amygdala
(Frontiers Media, 2019-08-20)
Adult neurogenesis persists in the adult hippocampus due to the presence of multipotent neural stem cells (NSCs). Hippocampal neurogenesis is involved in a range of cognitive functions and is tightly regulated by neuronal ...
Association Between Medication Adherence and Oxidative Stress in Patients With First-Episode Mania
(Frontiers Media, 2019-03-26)
Poor adherence is a major problem in patients with manic episodes that impairs functionality and has unknown effects on oxidative stress. The objective of this study was to analyze the relationship between adherence to ...
High-Altitude Cognitive Impairment Is Prevented by Enriched Environment Including Exercise via VEGF Signaling
(Frontiers Media, 2019)
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive impairment, mostly attributed to changes in brain perfusion and consequently neuronal death. Enriched environment and voluntary exercise ...
Amyotrophic lateral sclerosis: a complex syndrome that needs an integrated research approach
(Wolters Kluwer, 2019-02)
Amyotrophic lateral sclerosis, the most common neurodegenerative disease affecting motor neurons, lacks an effective treatment. A small fraction of amyotrophic lateral sclerosis cases have a familial origin, related to ...
Purinergic P2X4 receptors modulate neuroinflammation and repair in experimental multiple sclerosis
(2019-02-25)
La microglía examina el microambiente del sistema nervioso central para detectar señales de lesión o infección, y es esencial para el inicio y resolución de la inflamación inducida por patógenos o daño en los tejidos. ...
Delayed Diagnosis of an Eating Disorder in a Male Patient With Superior Mesenteric Artery Syndrome: Results From a Case Study
(Frontiers Media, 2019-10-15)
Background: Eating disorders (EDs) are serious and life-threatening mental diseases characterized by abnormal or altered eating habits. The prevalence is variable, being influenced by diverse sociocultural factors. ...