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An Overground Robotic Gait Training Program for People With Multiple Sclerosis: A Protocol for a Randomized Clinical Trial
(Frontiers Media, 2020)
Maintaining the ability to walk is one of the significant challenges in people with multiple sclerosis (MS) for keeping a good quality of life as the disease and the aging process progresses. Overground robotic (OR) wearable ...
Ingurune aberastuaren eragina MK-801 eskizofrenia aimalia-ereduan: hobekuntza kognitiboaren oinarri neurokimikoak
(2018-02-01)
Ingurune aberastua (IA) erabilera anitzeko eta balio terapeutiko handiko tresna da, baina gaixotasunneuropsikiatrikoetan duen balio potentziala ez da sakon aztertu. Ingurune aberastuak eskizofreniarensintoma kognitiboengan ...
Detección prenatal y seguimieto postnatal de las anomalías congénitas del sistema nervioso central.
(2018-01-19)
Las anomalías congénitas del Sistema Nervioso Central (ACSNC) se dan en el 1% de los nacimientos y suponen una causa importante de muerte neonatal y discapacidad a largo plazo. El diagnóstico suele realizarse a nivel ...
Influencia de la región n-terminal de la proteína del prion en la susceptibilidad al mal plegamiento, mantenimiento de las características de la cepa y neurotoxicidad.
(2018-02-22)
Las enfermedades priónicas, también conocidas como encefalopatías espongiformes transmisibles (EETs), son enfermedades neurodegenerativas que afectan a humanos y animales, y para las que no existe cura. En su patogénesis ...
Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injury
(Biomed Central, 2017-07-24)
Background: FTY720 (fingolimod, Gilenya (TM)) is an oral, blood-brain barrier (BBB)-passing drug approved as immunomodulatory treatment for relapsing-remitting form of the multiple sclerosis (MS). In addition, FTY720 exerts ...
Organotypic Cultures as a Model to Study Adult Neurogenesis in CNS Disorders
(Hindawi, 2016)
Neural regeneration resides in certain specific regions of adult CNS. Adult neurogenesis occurs throughout life, especially from the subgranular zone of hippocampus and the subventricular zone, and can be modulated in ...
Microglial phagocytosis of apoptotic cells triggers a neuromodulatory program that supports neurogenesis.
(2018-07-24)
Durante la neurgónesis del hipocampo adulto, la mayoría de las células recién nacidas mueren por apoptosis y son rápidamente eliminadas por la microglía residente del cerebro mediante el proceso denominado fagocitosis. En ...
Subclinical Depressive Symptoms and Continued Cannabis Use: Predictors of Negative Outcomes in First Episode Psychosis
(Public Library Science, 2015-04-15)
Background
Although depressive symptoms in first episode psychosis have been associated with cannabis abuse, their influence on the long-term functional course of FEP patients who abuse cannabis is unknown. The aims of ...
The role of purinergic receptor A1 in neurogenesis modulation from subventricular zone
(2016-06-16)
La neurogénesis continúa en la edad adulta en regiones específicas del cerebro como la zona subgranular del hipocampo y la zona subventricular (SVZ) de los ventrículos laterales. Resultados previos de nuestro laboratorio ...
Oligodendrocyte differentiation from adult multipotent stem cells is modulated by glutamate
(Nature Publishing Group, 2012-02)
We used multipotent stem cells (MSCs) derived from the young rat subventricular zone (SVZ) to study the effects of glutamate in oligodendrocyte maturation. Glutamate stimulated oligodendrocyte differentiation from SVZ-derived ...