Search
Now showing items 51-60 of 502
Neddylationin Schwann cell myelination
(2022-07-26)
En esta tesis, hemos encontrado que la modificación postraduccional llamada neddylationes un regulador crítico de la mielinización en células de Schwann. El silenciamiento genético en célulasde Schwann del gen Nae1 (llamado ...
Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model : mechanism for deficient glutamatergic transmission?
(BioMed Central, 2011-07-30)
Astrocytes are fundamental for brain homeostasis and the progression and outcome of many neuropathologies including Alzheimer's disease (AD). In the triple transgenic mouse model of AD (3xTg-AD) generalised hippocampal ...
Effectiveness of a Multi-Component Smoking Cessation Support Programme (McSCSP) for Patients with Severe Mental Disorders: Study Design
(MDPI, 2014-01)
Only a few studies have examined the efficacy and safety of smoking cessation programmes in patients with mental disorders. The aim of this paper is to describe in detail the methodology used in the study as well as the ...
Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease
(Portland Press, 2011)
The EC (entorhinal cortex) is fundamental for cognitive and mnesic functions. Thus damage to this area appears as a key element in the progression of AD (Alzheimer's disease), resulting in memory deficits arising from ...
Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
(Frontiers Research Foundation, 2013-01)
Microglia are the resident brain macrophages and they have been traditionally studied as orchestrators of the brain inflammatory response during infections and disease. In addition, microglia has a more benign, less explored ...
Utilidad de la monitorización terapéutica de antipsicóticos de segunda generación en la práctica clínica de los primeros episodios psicóticos
(2016-11-15)
Pocos estudios han valorado la utilidad de la monitorización terapéutica de fármacos (MTF) en la estimación del efecto de los antipsicóticos de segunda generación (ASG) en los pacientes con psicosis. Dichos trabajos se han ...
Impacto de la atención paliativa en el grado de satisfacción percibida por los familiares del paciente en situación de final de vida en el área de Bizkaia
(2016-06-14)
El paciente paliativo es un paciente diferente al resto, precisa mayor atención, personalizada, y adecuada a cada momento, con reevaluación constante motivada por cambios en su estado y complejidad. La atención al paciente ...
Grafted Human Embryonic Progenitors Expressing Neurogenin-2 Stimulate Axonal Sprouting and Improve Motor Recovery after Severe Spinal Cord Injury
(Public Library of Science, 2010-12-30)
Background: Spinal cord injury (SCI) is a widely spread pathology with currently no effective treatment for any symptom. Regenerative medicine through cell transplantation is a very attractive strategy and may be used in ...
Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain)
(BioMed Central, 2008-10-15)
Background: Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing. Dementia is one of the most significant public health problem. In recent years, the role of vascular ...
Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord
(BioMed Central, 2011-10-10)
Background: The adult central nervous system (CNS) contains different populations of immature cells that could possibly be used to repair brain and spinal cord lesions. The diversity and the properties of these cells in ...