dc.contributor.author | González Pinto Arrillaga, Ana María | |
dc.contributor.author | Martínez Cengotitabengoa, Mónica | |
dc.contributor.author | Arango, Celso | |
dc.contributor.author | Baeza, Inmaculada | |
dc.contributor.author | Otero Cuesta, Soraya | |
dc.contributor.author | Graell Berna, Montserrat | |
dc.contributor.author | Soutullo, César | |
dc.contributor.author | Leza, Juan Carlos | |
dc.contributor.author | Micó, Juan Antonio | |
dc.date.accessioned | 2013-05-20T17:57:11Z | |
dc.date.available | 2013-05-20T17:57:11Z | |
dc.date.issued | 2012-11-16 | |
dc.identifier.citation | BMC Psychiatry 12(200) : (2012) | es |
dc.identifier.issn | 1471-244X | |
dc.identifier.uri | http://hdl.handle.net/10810/10136 | |
dc.description.abstract | [EN] Our objective was to determine antioxidant defence activity in healthy controls (HC) and healthy unaffected second-degree relatives of patients with early onset psychosis (HC-FHP),and to assess its relationship with familiar environment measured using the Family Environment Scale (FES).
Methods: We included 82 HC and 14 HC-FHP aged between 9 and 17 years. Total antioxidant status,lipid peroxidation, antioxidant enzyme activities and glutathione levels were determined in
blood samples.
Results:There was a significant decrease in the total antioxidant level in the HC-FHP group compared with the HC group (OR = 2.94; p = 0.009), but no between-group differences in the Global Assessment of Functioning (GAF) scale scores. For the FES, the HC-FHP group had significantly higher scores in the cohesion (p = 0.007) and intellectual-cultural dimensions (p=0.025). After adjusting for these two FES dimensions, total antioxidant status remained
significantly different between groups (OR = 10.86, p = 0.009). | es |
dc.language.iso | eng | es |
dc.publisher | BioMed Central | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | oxidative stress | es |
dc.subject | family environment | es |
dc.subject | psychosis | es |
dc.subject | schizophrenia | es |
dc.subject | antioxidant enzymes | es |
dc.title | Antioxidant defense system and family environment in adolescents with family history of psychosis | es |
dc.type | info:eu-repo/semantics/article | es |
dc.rights.holder | © 2012 Gonzalez-Pinto et al.
This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | es |
dc.relation.publisherversion | http://www.biomedcentral.com/1471-244X/12/200 | es |
dc.identifier.doi | 10.1186/1471-244X-12-200 | |
dc.departamentoes | Neurociencias | es_ES |
dc.departamentoeu | Neurozientziak | es_ES |
dc.subject.categoria | PSYCHIATRY AND MENTAL HEALTH | |