dc.contributor.author | Mauriño, Jorge | |
dc.contributor.author | Sanjuán, Julio | |
dc.contributor.author | Haro, Josep Maria | |
dc.contributor.author | Díez, Teresa | |
dc.contributor.author | Ballesteros Rodríguez, Francisco Javier | |
dc.date.accessioned | 2014-02-20T17:47:22Z | |
dc.date.available | 2014-02-20T17:47:22Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Patient Preference and Adherence 5 : 471-474 (2011) | es |
dc.identifier.issn | 1177-889X | |
dc.identifier.uri | http://hdl.handle.net/10810/11593 | |
dc.description.abstract | Objective: The subjective experience of psychotic patients toward treatment is a key factor in medication adherence, quality of life, and clinical outcome. The aim of this study was to assess the subjective well-being in patients with schizophrenia and to examine its relationship with the presence and severity of depressive symptoms.
Methods: A multicenter, cross-sectional study was conducted with clinically stable outpatients diagnosed with schizophrenia. The Subjective Well-Being under Neuroleptic Scale - short version (SWN-K) and the Calgary Depression Scale for Schizophrenia (CDSS) were used to gather information on well-being and the presence and severity of depressive symptoms, respectively. Spearman's rank correlation was used to assess the associations between the SWN-K total score, its five subscales, and the CDSS total score. Discriminative validity was evaluated against that criterion by analysing the area under the curve (AUC).
Results: Ninety-seven patients were included in the study. Mean age was 35 years (standard deviation = 10) and 72% were male. Both the total SWN-K scale and its five subscales correlated inversely and significantly with the CDSS total score (P < 0.0001). The highest correlation was observed for the total SWN-K (Spearman's rank order correlation [ rho] = -0.59), being the other correlations: mental functioning (-0.47), social integration (-0.46), emotional regulation (-0.51), physical functioning (-0.48), and self-control (-0.41). A total of 33 patients (34%) were classified as depressed. Total SWN-K showed the highest AUC when discriminating between depressive severity levels (0.84), followed by emotional regulation (0.80), social integration (0.78), physical functioning and self-control (0.77), and mental functioning (0.73). Total SWN-K and its five subscales showed a significant linear trend against CDSS severity levels (P < 0.001).
Conclusion: The presence of moderate to severe depressive symptoms was relatively high, and correlated inversely with patients' subjective well-being. Routine assessment of patient-reported measures in patients with schizophrenia might reduce potential discrepancy between patient and physician assessment, increase therapeutic alliance, and improve outcome. | es |
dc.description.sponsorship | AstraZeneca Spain | es |
dc.language.iso | eng | es |
dc.publisher | Dove Medical Press | es |
dc.rights | info:eu-repo/semantics/openAccess | es |
dc.subject | schizophrenia | es |
dc.subject | subjective well being | es |
dc.subject | patient reported outcome | es |
dc.subject | depressive symptoms | es |
dc.title | Impact of depressive symptoms on subjective well-being: the importance of patient-reported outcomes in schizophrenia | es |
dc.type | info:eu-repo/semantics/article | es |
dc.rights.holder | © 2011 Mauriño et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. | es |
dc.relation.publisherversion | http://www.dovepress.com/impact-of-depressive-symptoms-on-subjective-well-being-the-importance--peer-reviewed-article-PPA | es |
dc.identifier.doi | 10.2147/PPA.S24479 | |
dc.departamentoes | Neurociencias | es_ES |
dc.departamentoeu | Neurozientziak | es_ES |
dc.subject.categoria | HEALTH POLICY AND SERVICES | |
dc.subject.categoria | SOCIAL SCIENCES | |
dc.subject.categoria | PHARMACOLOGY, TOXICOLOGY AND PHARMACEUTICS | |
dc.subject.categoria | MEDICINE | |