Show simple item record

dc.contributor.authorMauriño, Jorge
dc.contributor.authorSanjúan, Julio
dc.contributor.authorHaro, Josep Maria
dc.contributor.authorDíez, Teresa
dc.contributor.authorBallesteros Rodríguez, Francisco Javier ORCID
dc.date.accessioned2014-02-20T17:47:22Z
dc.date.available2014-02-20T17:47:22Z
dc.date.issued2011
dc.identifier.citationPatient Preference and Adherence 5 : 471-474 (2011)es
dc.identifier.issn1177-889X
dc.identifier.urihttp://hdl.handle.net/10810/11593
dc.description.abstractObjective: The subjective experience of psychotic patients toward treatment is a key factor in medication adherence, quality of life, and clinical outcome. The aim of this study was to assess the subjective well-being in patients with schizophrenia and to examine its relationship with the presence and severity of depressive symptoms. Methods: A multicenter, cross-sectional study was conducted with clinically stable outpatients diagnosed with schizophrenia. The Subjective Well-Being under Neuroleptic Scale - short version (SWN-K) and the Calgary Depression Scale for Schizophrenia (CDSS) were used to gather information on well-being and the presence and severity of depressive symptoms, respectively. Spearman's rank correlation was used to assess the associations between the SWN-K total score, its five subscales, and the CDSS total score. Discriminative validity was evaluated against that criterion by analysing the area under the curve (AUC). Results: Ninety-seven patients were included in the study. Mean age was 35 years (standard deviation = 10) and 72% were male. Both the total SWN-K scale and its five subscales correlated inversely and significantly with the CDSS total score (P < 0.0001). The highest correlation was observed for the total SWN-K (Spearman's rank order correlation [ rho] = -0.59), being the other correlations: mental functioning (-0.47), social integration (-0.46), emotional regulation (-0.51), physical functioning (-0.48), and self-control (-0.41). A total of 33 patients (34%) were classified as depressed. Total SWN-K showed the highest AUC when discriminating between depressive severity levels (0.84), followed by emotional regulation (0.80), social integration (0.78), physical functioning and self-control (0.77), and mental functioning (0.73). Total SWN-K and its five subscales showed a significant linear trend against CDSS severity levels (P < 0.001). Conclusion: The presence of moderate to severe depressive symptoms was relatively high, and correlated inversely with patients' subjective well-being. Routine assessment of patient-reported measures in patients with schizophrenia might reduce potential discrepancy between patient and physician assessment, increase therapeutic alliance, and improve outcome.es
dc.description.sponsorshipAstraZeneca Spaines
dc.language.isoenges
dc.publisherDove Medical Presses
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectschizophreniaes
dc.subjectsubjective well beinges
dc.subjectpatient reported outcomees
dc.subjectdepressive symptomses
dc.titleImpact of depressive symptoms on subjective well-being: the importance of patient-reported outcomes in schizophreniaes
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© 2011 Mauriño et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.es
dc.relation.publisherversionhttp://www.dovepress.com/impact-of-depressive-symptoms-on-subjective-well-being-the-importance--peer-reviewed-article-PPAes
dc.identifier.doi10.2147/PPA.S24479
dc.departamentoesNeurocienciases_ES
dc.departamentoeuNeurozientziakes_ES
dc.subject.categoriaHEALTH POLICY AND SERVICES
dc.subject.categoriaSOCIAL SCIENCES
dc.subject.categoriaPHARMACOLOGY, TOXICOLOGY AND PHARMACEUTICS
dc.subject.categoriaMEDICINE


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record