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Now showing items 41-50 of 63
Cognition, inflammation and related risk factors in suicide attempts
(2022-12-14)
La conducta suicida es un problema de salud global que causa alrededor de 800.000 muertes anuales en el mundo y está asociada a discapacidad y deterioro funcional. De acuerdo al modelo de estrés-diátesis y el enfoque ...
Gliogenesis from the subventricular zone after brain ischemia.
(2022-03-14)
Brain stroke is the second cause of death worldwide. Among the cerebrovascular accidents, ischemic stroke is the most common. It is caused by an interruption of blood flow, and it is characterized by sudden neuronal death ...
Lysophosphatidic acid receptor 1 labels seizure-induced hippocampal reactive neural stem cells and controls their activation.
(2018-11-27)
En la regulación de la neurogénesis hipocampal adulta, un paso fundamental es la división de las células madre neurales (NSCs) ya que, tras activarse, se dividen varias veces consecutivas y se diferencian después en ...
Biophysical properties of aqueous humour in ocular pathologies
(2016-05-30)
El limbo corneoescleral contiene estructuras diseñadas para evacuar el humor acuso desde la cámara anterior del ojo hacia la circulación general. Estos elementos se encuentran entre el espolón escleral y la línea de Schwalbe ...
Study of the long-lasting effects of ethanol consumption during adolescence on cannabinoid type 1 receptor-dependent synaptic transmission and plasticity in dentate gyrus synapses.
(2018-10-17)
El consumo excesivo de alcohol, especialmente durante la adolescencia, es una preocupación generalizada de salud pública. Investigaciones en la última década han puesto de manifiesto que el consumo de etanol (EtOH) y el ...
Effects of acute and chronic restraint stress during adolescence on endocannabinoid-mediated synaptic plasticity in the mouse hippocampal dentate gyrus.
(2019-06-28)
Our society lives embedded in stress. This causes numerous environmental factors that precipitate and exacerbate psychiatric disorders, such as anxiety and depression. In all organisms, stress is recognized as an adaptive ...
Purinergic P2X4 receptors modulate neuroinflammation and repair in experimental multiple sclerosis
(2019-02-25)
La microglía examina el microambiente del sistema nervioso central para detectar señales de lesión o infección, y es esencial para el inicio y resolución de la inflamación inducida por patógenos o daño en los tejidos. ...
Synaptic dysfunction in Parkinson's Disease: functional and ultrastructural study of the striatal synapses in an animal model of progressive parkinsonism
(2021-02-26)
This Ph.D. project involves the temporal sequence of the earliest functional and structural events in the striatal synapses in a rat model of progressive parkinsonism induced by overexpression of human ¿-synuclein (h¿-syn) ...
High resolution imaging to unveil the subcellular layout of the cannabinoid type-1 receptor in rodent models of brain disease
(2020-02-28)
The present Thesis focuses on the description of new subcellular localizations of CB1 receptors in normal brain and the study of the CB1 receptor expression in certain pathophysiological states. Different histological ...
Signaling pathwais in oligodentdrocytes to promote myelin remodeling
(2022-03-16)
Oligodendrocytes make myelin and support axons metabolically with lactate. Experience and neuronal activity can induce dynamic changes in myelination during development and in adult life, suggesting a new form of plasticity ...