Physico-chemical interactions between compartment-forming lipids and other prebiotically relevant biomolecules
Olasagasti Arsuaga, Félix
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EPOV 2012: From Planets to Life – Colloquium of the CNRS Interdisciplinary Initiative “Planetary Environments and Origins of Life” 2 2014 : (2014) Article ID 05001
Lipids are essential constituents of contemporary living cells, serving as structural molecules that are necessary to form membranous compartments. Amphiphilic lipid-like molecules may also have contributed to prebiotic chemical evolution by promoting the synthesis, aggregation and cooperative encapsulation of other biomolecules. The resulting compartments would allow systems of molecules to be maintained that represent microscopic experiments in a natural version of combinatorial chemistry. Here we address these possibilities and describe recent results related to interactions between amphiphiles and other biomolecules during early evolution toward the first living cells.