Browsing Artículos by Author "Goñi, Isabel"
Now showing items 1-5 of 5
-
Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis
García Arnáez, Iñaki; Romero Gavilán, Francisco; Cerqueira, Andreia; Elortza, Felix; Azkargorta, Mikel; Muñoz Guzón, Fernando María; Mata Roig, Manuel; Martín de Llano, José Javier; Suay, Julio; Gurruchaga Torrecilla, María Dolores ; Goñi Echave, Isabel María del Coro (Elsevier, 2022-12)Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological ... -
Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes
García Arnáez, Iñaki; Cerqueira, Andreia; Romero Gavilán, Francisco; Elortza, Felix; Azkargorta, Mikel; Iloro, Ibon; Suay, Julio; Goñi Echave, Isabel María del Coro ; Gurruchaga Torrecilla, María Dolores (Elsevier, 2022-12)Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of os-teoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ... -
Influence of Calcium Ion-Modified Implant Surfaces in Protein Adsorption and Implant Integration
Anitua Aldekoa, Eduardo; Cerqueira, Andreia; Romero Gavilán, Francisco; García Arnáez, Iñaki; Martínez Ramos, Cristina; Ozturan, Seda; Azkargorta, Mikel; Elortza, Felix; Gurruchaga Torrecilla, María Dolores ; Goñi Echave, Isabel María del Coro ; Suay, Julio; Tejero, Ricardo (Springer, 2021-04-21)Background Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ... -
Protein adsorption/desorption dynamics on Ca-enriched titanium surfaces: biological implications
Romero Gavilán, Francisco; Cerqueira, Andreia; Anitua Aldekoa, Eduardo; Tejero, Ricardo; García Arnáez, Iñaki; Martínez Ramos, Cristina; Ozturan, Seda; Izquierdo, Raúl; Azkargorta, Mikel; Elortza, Felix; Gurruchaga Torrecilla, María Dolores ; Goñi Echave, Isabel María del Coro ; Suay, Julio (Springer, 2021-08-27)Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ... -
Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating
Cerqueira, Andreia; Romero Gavilán, Francisco; Helmholz, Heike; Azkargorta, Mikel; Elortza, Felix; Gurruchaga Torrecilla, María Dolores ; Goñi Echave, Isabel María del Coro ; Willumeit-Römer, Regine; Suay, Julio (American Chemical Society, 2023-05)New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused ...