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      Cellular and Synaptic Dysfunctions in Parkinson's Disease: Stepping Out of the Striatum 

      Mallet, Nicolas; Delgado Zabalza, Lorena; Chazalon, Marine; Miguélez Palomo, Cristina; Baufreton, Jérôme (MDPI, 2019-08-29)
      The basal ganglia (BG) are a collection of interconnected subcortical nuclei that participate in a great variety of functions, ranging from motor programming and execution to procedural learning, cognition, and emotions. ...
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      D5 dopamine receptors control glutamatergic AMPA transmission between the motor cortex and subthalamic nucleus 

      Froux, Lionel; Le Bon-Jego, Morgane; Miguélez Palomo, Cristina; Normand, Elisabeth; Morin, Stephanie; Fioramonti, Stéphanie; Barresi, Massimo; Frick, Andreas; Baufreton, Jérôme; Taupignon, Anne (Nature Publishing, 2018-06-11)
      Corticofugal fibers target the subthalamic nucleus (STN), a component nucleus of the basal ganglia, in addition to the striatum, their main input. The cortico-subthalamic, or hyperdirect, pathway, is thought to supplement ...
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      Dopamine D4 Receptor Is a Regulator of Morphine-Induced Plasticity in the Rat Dorsal Striatum 

      Rivera, Alicia; Suárez-Boomgaard, Diana; Miguélez Palomo, Cristina; Valderrama-Carvajal, Alejandra; Baufreton, Jérôme; Shumilov, Kirill; Taupignon, Anne; Gago, Belén; Real, M. Ángeles (MDPI, 2021-12-23)
      Long-term exposition to morphine elicits structural and synaptic plasticity in reward-related regions of the brain, playing a critical role in addiction. However, morphine-induced neuroadaptations in the dorsal striatum ...
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      GAT-3 Dysfunction Generates Tonic Inhibition in Exter nal Globus Pallidus Neurons in Parkinsonian Rodents 

      Chazalon, Marine; Paredes Rodríguez, Elena; Morin, Stéphanie; Martinez, Audrey; Cristóvão-Ferreira, Sofia; Vaz, Sandra; Sebastiao, Ana; Panatier, Aude; Boué-Grabot, Eric; Miguélez Palomo, Cristina; Baufreton, Jérôme (Cell Press, 2018-05-08)
      The external globus pallidus (GP) is a key GABAergic hub in the basal ganglia (BG) circuitry, a neuronal network involved in motor control. In Parkinson's disease (PD), the rate and pattern of activity of GP neurons are ...