Browsing Artículos by Author "Beaskoetxea Lejarzegi, Javier"
Now showing items 1-3 of 3
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A Proteomic Approach for Systematic Mapping of Substrates of Human Deubiquitinating Enzymes
Ramírez Sánchez, Juan Manuel; Prieto Agujeta, Gorka
; Olazabal Herrero, Ane; Borràs, Eva; Fernandez-Vigo, Elvira; Alduntzin Egizurain, Unai
; Osinalde Moraleja, Nerea
; Beaskoetxea Lejarzegi, Javier; Lectez, Benoît; Aloria Escolastico, Kerman; Rodríguez Pérez, José Antonio
; Paradela, Alberto; Sabidó, Eduard; Muñoz, Javier; Corrales, Fernando; Arizmendi Bastarrika, Jesús María
; Mayor Martínez, Ugo
(MDPI, 2021-05-03)
The human genome contains nearly 100 deubiquitinating enzymes (DUBs) responsible for removing ubiquitin moieties from a large variety of substrates. Which DUBs are responsible for targeting which substrates remain mostly ... -
Detailed dissection of UBE3A-mediated DDI1 ubiquitination.
Elu Arantzamendi, Nagore; Osinalde Moraleja, Nerea
; Beaskoetxea Lejarzegi, Javier; Ramírez Sánchez, Juan Manuel
; Lectez, Benoît; Aloria Escolastico, Kerman; Rodríguez Pérez, José Antonio
; Arizmendi Bastarrika, Jesús María
; Mayor Martínez, Ugo
(Frontiers, 2019-05-03)
The ubiquitin E3 ligase UBE3A has been widely reported to interact with the proteasome, but it is still unclear how this enzyme regulates by ubiquitination the different proteasomal subunits. The proteasome receptor DDI1 ... -
In-Depth Proteomic Characterization of Classical and Non-Classical Monocyte Subsets
Segura, Victor; Valero, M. Luz; Cantero, Laura; Muñoz, Javier; Zarzuela, Eduardo; García, Fernando; Aloria Escolastico, Kerman; Beaskoetxea Lejarzegi, Javier; Arizmendi Bastarrika, Jesús María; Navajas, Rosana; Paradela, Alberto; Díez, Paula; Degano, Rosa M.; Fuentes, Manuel; Orfao, Alberto; García Montero, Andrés; Garin-Muga, Alba; Corrales, Fernando J.; Sánchez del Pino, Manuel M. (MDPI, 2018-02-05)
Monocytes are bone marrow-derived leukocytes that are part of the innate immune system. Monocytes are divided into three subsets: classical, intermediate and non-classical, which can be differentiated by their expression ...