Browsing Artículos by Author "Bediaga Bañeres, Harbil"
Now showing items 1-2 of 2
-
On the additive artificial intelligence-based discovery of nanoparticle neurodegenerative disease drug delivery systems
He, Shan; Segura Abarrategi, Julen; Bediaga Bañeres, Harbil; Arrasate Gil, Sonia; González Díaz, Humberto (Beilstein-Institut, 2024)Neurodegenerative diseases are characterized by slowly progressing neuronal cell death. Conventional drug treatment strategies often fail because of poor solubility, low bioavailability, and the inability of the drugs to ... -
OptiMo-LDLr: an integrated In silico model with enhanced predictive power for LDL receptor variants, unraveling hot spot pathogenic residues
Larrea Sebal, Asier; Sasiain, Iñaki; Jebari Benslaiman, Shifa; Galicia García, Unai; Belloso Uribe, Kepa; Benito Vicente, Asier; Gracia Rubio, Irene; Bediaga Bañeres, Harbil; Arrasate Gil, Sonia; Cenarro Lagunas, Ana; Civeira Murillo, Fernando; González Díaz, Humberto; Martín Plágaro, César Augusto (Wiley, 2024-04)Familial hypercholesterolemia (FH) is an inherited metabolic disease affecting cholesterol metabolism, with 90% of cases caused by mutations in the LDL receptor gene (LDLR), primarily missense mutations. This study aims ...