BackBrowsing Artículos by Author "Bergara Jauregui, Aitor"
Now showing items 1-9 of 9
-
An Epilepsy-Causing Mutation Leads to Co-Translational Misfolding of the Kv7.2 Channel
; ; ; ; ; ; Núñez Viadero, Eider
; ; ; ; ; (Springer, 2021-05-21)
BACKGROUND: The amino acid sequence of proteins generally carries all the necessary information for acquisition of native conformations, but the vectorial nature of translation can additionally determine the folding outcome. ... -
Anomalous High‐Temperature Superconductivity in YH6
Troyan, Ivan A.; Semenok, Dmitrii V.; Kvashnin, Alexander G.; Sadakov, Andrey V.; Sobolevskiy, Oleg A.; Pudalov, Vladimir M.; Ivanova, Anna G.; Prakapenka, Vitali B.; Greenberg, Eran; Gavriliuk, Alexander G.; Lyubutin, Igor S.; Struzhkin, Viktor V.; Bergara Jauregui, Aitor; Errea Lope, Ion; Bianco, Raffaello; Calandra, Matteo; Mauri, Francesco; Monacelli, Lorenzo; Akashi, Ryosuke; Oganov, Artem R. (Wiley-VCH GmbH, 2021-03-10)
Pressure‐stabilized hydrides are a new rapidly growing class of high‐temperature superconductors, which is believed to be described within the conventional phonon‐mediated mechanism of coupling. Here, the synthesis of one ... -
Cubic Hall viscosity in three-dimensional topological semimetals
(American Physical Society, 2021-09-16)The nondissipative (Hall) viscosity is known to play an interesting role in two-dimensional (2D) topological states of matter, in the hydrodynamic regime of correlated materials, and in classical active fluids with broken ... -
Do calmodulin binding IQ motifs have built-in capping domains?
; ; Núñez Viadero, Eider; ; ; ; ; ; ; ; (Wiley, 2021-08-15)
Most calmodulin (CaM) targets are alpha-helices. It is not clear if CaM induces the adoption of an alpha-helix configuration to its targets or if those targets are selected as they spontaneously adopt an alpha-helical ... -
Identification of Riluzole Derivatives as Novel Calmodulin Inhibitors with Neuroprotective Activity by a joint synthesis, biosensor, and computational guided strategy
; ; ; ; ; ; ; ; ; ; Núñez Viadero, Eider; ; ; ; ; ; ; ; ; (Elsevier, 2024-04-17)
The development of new molecules for the treatment of calmodulin related cardiovascular or neurodegenerative diseases is an interesting goal. In this work, we introduce a novel strategy with four main steps: (1) chemical ... -
MLe-KCNQ2: An Artificial Intelligence Model for the Prognosis of Missense KCNQ2 Gene Variants
; ; ; ; Núñez Viadero, Eider; ; ; ; ; Gallego Muñoz, Mónica ; Casis Sáenz, Oscar ; ; ; (MDPI, 2024-03-02)
Despite the increasing availability of genomic data and enhanced data analysis procedures, predicting the severity of associated diseases remains elusive in the absence of clinical descriptors. To address this challenge, ... -
Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel
; ; ; ; Núñez Viadero, Eider; ; ; (Elsevier, 2023-02)
The family of small-conductance Ca2+-activated potassium ion channels (SK channels) is composed of four members (SK1, SK2, SK3, and SK4) involved in neuron-firing regulation. The gating of these channels depends on the ... -
Phase transitions of alkaline-earth metal sulfides under pressure
(IOP Publishing Ltd., 2021-06-21)[EN] Wehave systematically explored the crystal structures of alkaline-earth metal sulfides under pressure by using a swarm-intelligence structural prediction method. At low pressures we successfully reproduced their ... -
Spectral and optical properties of Ag3Au(Se2,Te2) and dark matterdetection
(IOP, 2020-01-01)Paper • The following article is Open access Spectral and optical properties of Ag3Au(Se2,Te2) and dark matter detection M-Á Sánchez-Martínez6,1 , I Robredo6,2,3, A Bidaurrazaga3, A Bergara2,3,4, F de Juan2,5, A G ...